Native Human CXCL9

• Cat.No.: CXCL9-30233TH
• Product Overview: Human MIG.

Specification

• Description: The function of this gene has not been specifically defined; however, it is thought to be involved in T cell trafficking. This gene has been localized to 4q21 with INP10, which is also a member of the chemokine family of cytokines.
• Source: E. coli
• Form: Lyophilised
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: Human MIG is an 11.7 kDa protein containing 103 amino acid residues:TPVVRKGRCSCISTNQGTIHLQSLKDLKQFAPSPSCEKIEIIATLK NGVQTCLNPDSADVKELIKKWEKQVSQKKKQKNGKKH QKKKVLKVRKSQRSRQKKTT
• Sequence Similarities: Belongs to the intercrine alpha (chemokine CxC) family.
• Tag: Non

Gene Information

• Gene Name: CXCL9 chemokine (C-X-C motif) ligand 9 [ Homo sapiens ]
• Official Symbol: CXCL9
• Synonyms: CXCL9; chemokine (C-X-C motif) ligand 9; CMK, MIG, monokine induced by gamma interferon; C-X-C motif chemokine 9; crg 10; Humig; SCYB9
• Gene ID: 4283
• mRNA Refseq: NM_002416
• Protein Refseq: NP_002407
• MIM: 601704
• Uniprot ID: Q07325
• Chromosome Location: 4q21
• Pathway: CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem
• Function: chemokine activity; cytokine activity

Reviews

02/21/2023

Customer service promptly feedback my requests, technical staff timely solve the problems that arise.

04/01/2022

The protein composition was stable and the concentration was high, which allowed me to obtain satisfactory experimental results.

Q&As

What is the relationship between CXCL9 and the chemokine receptor CXCR3?

CXCL9 can bind specifically to CXCR3 and accumulate at sites of inflammation, thereby inducing and exacerbating the inflammatory response.

Do you offer CXCL9 fused with other tags?

Yes, we will provide you with the most suitable labels according to your experimental needs.

Can CXCL9 be detected in lymphoid tissue under normal physiological conditions?

No, CXCL9 can only be detected when the organism is inflamed or infected.

CXCL9 is secreted by which cells?

CXCL9 is mainly secreted by endothelial cells and monocytes.

What diseases has CXCL9 been closely associated with the study of?

CXCL9 has been linked to pulmonary embolism, asthma and breast cancer research.