Active Recombinant Mouse Il9 Protein

• Cat.No.: Il9-119M
• Product Overview: Purified recombinant protein of Mouse interleukin 9 (Il9) without tag was expressed in E.coli.

Specification

• Description: Supports IL-2 independent and IL-4 independent growth of helper T-cells.
• Source: E. coli
• Species: Mouse
• Bio-activity: The ED50 as determined by the dose-dependent proliferation of human MO7e cells is > 0.5 ng/ml, corresponding to a specific activity of > 2 x 10^6 units/mg.
• Molecular Mass: 14.3 kDa
• AA Sequence: MQRCSTTWGIRDTNYLIENLKDDPP SKCSCSGNVTSCLCLSVPTDDCTTP CYREGLLQLTNATQKSRLLPVFHRV KRIVEVLKNITCPSFSCEKPCNQTM AGNTMSFLKSLLGTFQKTEMQRQKS RP
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Purity: >95%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.
• Storage: Store at -80 centigrade.
• Storage Buffer: Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
• Reconstitution: Resuspend the protein in the desired concentration in proper buffer.

Gene Information

• Gene Name: Il9 interleukin 9 [ Mus musculus (house mouse) ]
• Official Symbol: Il9
• Synonyms: Il9; interleukin 9; P40; Il-9; interleukin-9; T-cell growth factor P40; cytokine P40
• Gene ID: 16198
• mRNA Refseq: NM_008373
• Protein Refseq: NP_032399
• UniProt ID: P15247

Reviews

08/04/2022

The anti-interference ability of IL9 was excellent in Western blot, which avoided the interference problem in the experiment.

04/14/2019

This protein has high catalytic efficiency, high safety and high expression level, and is a precious resource in the field of scientific research.

02/28/2019

The reproducibility of IL9 is very good, which can reduce the error in the experiment and improve the repeatability of the experiment.

Q&As

How is the clinical trial of IL9 progressing?

Several clinical trials are currently underway to evaluate the safety and effectiveness of IL9 in treating conditions such as asthma and allergies. However, the research is still in its early stages and more data are needed.

How to obtain IL9?

IL9 can be synthesized in the laboratory by biotechnological methods. Before clinical use, it needs to go through strict quality control and testing.

What is the action mechanism of IL9?

By binding to specific receptors, IL9 can activate relevant signaling pathways and regulate the development and function of immune cells. It can affect the activity of a variety of immune cells, such as T cells and macrophages.

Howthe relationship between IL9 and other related cytokines?

IL9 has cross-action with other cytokines, which can regulate the expression and function of each other. For example, IL9 can promote the production of IL4 and IL13, and IL4 and IL13 can also promote the secretion of IL9.

What are the clinical applications of IL9?

IL9 can be used to treat certain inflammatory diseases, such as asthma and skin allergies. It can regulate the response of the immune system and reduce the symptoms of related diseases.

What is the mechanism of action of IL9 in the treatment of asthma?

The mechanism of action of IL9 in asthma treatment is not fully understood, but studies have shown that it can reduce the infiltration of inflammatory cells and the release of inflammatory mediators, thereby reducing the symptoms of asthma.