IL9

  • Official Full Name

    interleukin 9

  • Overview

    The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
  • Synonyms

    IL9; interleukin 9; P40; HP40; IL-9; interleukin-9; cytokine P40; p40 cytokine; TTHUMP00000159423; T-cell growth factor p40; p40 T-cell and mast cell growth factor; homolog of mouse T cell and mast cell growth factor 40;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Transfected Stable Cell Lines
  • GMP Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus monkey
  • CHO
  • E.coli
  • HEK293
  • HEK293F
  • Hordeum Vulgare
  • Human Cells
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Mouse
  • Sf21 Insect Cell
  • Wheat Germ
  • Alexa Fluor 647
  • Biotin
  • C
  • His
  • DYKDDDDK
  • Fc
  • GST
  • His (Fc)
  • Avi
  • His(N
  • ter)
  • His|T7
  • HQ
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL9-476H Active Recombinant Human Interleukin 9 E.coli N/A
Human Il9-001H Active Recombinant Human Il9, HIgG1 Fc-tagged, mutant CHO Fc
Human Il9-002H Active Recombinant Human Il9, HIgG1 Fc-tagged CHO Fc
Human IL9-003H Active Recombinant Human IL9, MIgG2a Fc-tagged CHO Fc
Human IL9-8866H Active Recombinant Human IL9,His-tagged Hordeum Vulgare N/A
Human IL9-14214H Recombinant Human IL9, GST-tagged E.coli GST 31-144a.a.
Human IL9-374H Recombinant Human IL9, His tagged Insect Cell His
Human IL9-67H Recombinant Human IL9 protein E.coli N/A 126
Human IL9-5342H Recombinant Human Interleukin 9, HQ-tagged Hordeum Vulgare HQ
Human IL9-216H Recombinant Human Interleukin 9 Sf21 Insect Cell N/A
Human IL9-668H Recombinant Human IL9 protein, His & T7-tagged E.coli His/T7 Gln19~Ile144 (Accession # P15248)
Human IL9-28162TH Recombinant Human IL9, His-tagged His
Human IL9-618HCL Recombinant Human IL9 cell lysate Insect Cell N/A
Human DMABT-H19268 Mouse Anti-IL9 Monoclonal Antibody Mouse Biotin
Human IL9-115H Human Interleukin-9 (rDNA derived) Reference standard N/A
Human IL9-218H Recombinant Active Human IL9 Protein, His-tagged(N-ter) E.coli His(N-ter)
Human IL9-4291H Recombinant Human IL9 Protein (Met1-Ile144), C-His tagged Mammalian cells C-His Met1-Ile144
Human DMABT-H19270 Mouse Anti-IL9 Monoclonal Antibody Mouse Biotin
Human DMABT-H19269 Mouse Anti-IL9 Monoclonal Antibody Mouse Alexa Fluor 647
Human IL9-5165H Recombinant Human IL9 Protein, GST-tagged Wheat Germ GST
Human IL9-4292H Recombinant Human IL9 Protein (Gln19-Ile144), C-His tagged Mammalian cells C-His Gln19-Ile144
Human IL9-2327H Recombinant Human IL9 Protein, His-tagged E.coli N-His Gln19-Ile144
Human IL9-4324HG Active GMP Recombinant Human IL9 protein E.coli N/A
Human IL9-151H Recombinant Human IL9 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human IL9-5704HF Recombinant Full Length Human IL9 Protein, GST-tagged In Vitro Cell Free System GST 144 amino acids
Human IL9-192H Active Recombinant Human IL9 Protein E.coli
Human IL9-230I Active Recombinant Human IL9 Protein CHO
Human IL9-0312H Recombinant Human IL9 protein, His-tagged HEK293 His Gln19-Ile144
Human IL9-173H Active Recombinant Human IL9 Protein (Gln19-Ile144), N-His tagged, Animal-free, Carrier-free E.coli N-His Gln19-Ile144
Mouse Il9-002M Active Recombinant Mouse Il9, MIgG2a Fc-tagged CHO Fc
Mouse Il9-001M Active Recombinant Mouse Il9, MIgG2a Fc-tagged, mutant CHO Fc
Mouse Il9-477M Active Recombinant Mouse Interleukin 9 E.coli N/A
Mouse Il9-01M Active Recombinant Mouse Il9 Protein, His-Tagged E.coli His
Mouse Il9-78M Recombinant Mouse Il9 protein E.coli N/A 126
Mouse Il9-225M Recombinant Mouse Interleukin 9 Sf21 Insect Cell N/A
Mouse IL9-8181M Recombinant Mouse IL9 Protein Mammalian Cell His
Mouse Il9-63M Active Recombinant Mouse Il9 Protein (Gln19-Pro144), N-His tagged, Animal-free, Carrier-free E.coli N-His Gln19-Pro144
Mouse IL9-858M Active Recombinant Mouse IL9 Protein (Met1-Pro144), His-tagged Insect Cell His Met1-Pro144
Mouse Il9-1059M Recombinant Mouse Il9 Protein, His-tagged HEK293F N-His Gln19-Pro144
Mouse Il9-219M Recombinant Active Mouse IL9 Protein, His-tagged(N-ter) E.coli His(N-ter)
Mouse Il9-2175M Recombinant Mouse Il9 Protein E.coli N/A
Mouse IL9-4521M Recombinant Mouse IL9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Il9-119M Active Recombinant Mouse Il9 Protein E.coli
Mouse IL9-4521M-B Recombinant Mouse IL9 Protein Pre-coupled Magnetic Beads HEK293
Rat Il9-1117R Active Recombinant Rat Il9 Protein, His-tagged Insect Cell His
Rat Il9-676R Active Recombinant Rat Il9 Mammalian cells N/A
Rat Il9-2171R Recombinant Rat Il9 protein E.coli N/A 127
Rat Il9-1060R Recombinant Rat Il9 Protein, His-tagged HEK293F N-His Gln19-Ala144
Rat Il9-6385R Recombinant Rat Il9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Il9-1685R Recombinant Rat Il9 Protein, His-tagged E.coli N-His Gln19-Ala144
Rat Il9-6385R-B Recombinant Rat Il9 Protein Pre-coupled Magnetic Beads HEK293
Rhesus monkey IL9-2328R Recombinant Rhesus monkey IL9 Protein, His-tagged E.coli N-His Gln19-Ile144
Chicken IL9-3294C Recombinant Chicken IL9 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

IL9 involved in several pathways and played different roles in them. We selected most pathways IL9 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Asthma, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionOSTN;Ccl21a;Ifna15;CSF2RA;CXCL5;PLEKHO2;BMPR2;IL8L2;CXCL8
Jak-STAT signaling pathwayIRX1;LIF;IL9R;CSH;IL2RG;SOCS6;SOCS4;IFNA5;LEPB
AsthmaHLA-DOB;HLA-DRB1;HLA-DRB5;IL9;IL3;EPX;CD40LG;TNF;HLA-DOA

IL9 has several biochemical functions, for example, cytokine activity, growth factor activity, interleukin-9 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL9 itself. We selected most functions IL9 had, and list some proteins which have the same functions with IL9. You can find most of the proteins on our site.

Function Related Protein
cytokine activityGDF5;C1QTNF4;TNFSF13;CMTM1;Ccl9;AIMP1;IL17D;IL23;Il2
growth factor activityNDR1;REG1A;PRL2C2;Artn;ANGPTL3;INHBAA;THPO;BMP7;CSF1B
interleukin-9 receptor binding

IL9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL9 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL9.

Gene Family

IL

Research Area

Related articles

Venetz, D; Hess, C; et al. Glycosylation profiles determine extravasation and disease-targeting properties of armed antibodies. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:2000-2005(2015).
Hoelzinger, DB; Dominguez, AL; et al. Inhibition of Adaptive Immunity by IL9 Can Be Disrupted to Achieve Rapid T-cell Sensitization and Rejection of Progressive Tumor Challenges. CANCER RESEARCH 74:6845-6855(2014).
  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
08/04/2022

    The anti-interference ability of IL9 was excellent in Western blot, which avoided the interference problem in the experiment.

    04/14/2019

      This protein has high catalytic efficiency, high safety and high expression level, and is a precious resource in the field of scientific research.

      02/28/2019

        The reproducibility of IL9 is very good, which can reduce the error in the experiment and improve the repeatability of the experiment.

        Q&As (6)

        Ask a question
        How is the clinical trial of IL9 progressing? 09/05/2022

        Several clinical trials are currently underway to evaluate the safety and effectiveness of IL9 in treating conditions such as asthma and allergies. However, the research is still in its early stages and more data are needed.

        How to obtain IL9? 03/13/2022

        IL9 can be synthesized in the laboratory by biotechnological methods. Before clinical use, it needs to go through strict quality control and testing.

        What is the action mechanism of IL9? 09/22/2021

        By binding to specific receptors, IL9 can activate relevant signaling pathways and regulate the development and function of immune cells. It can affect the activity of a variety of immune cells, such as T cells and macrophages.

        Howthe relationship between IL9 and other related cytokines? 05/02/2020

        IL9 has cross-action with other cytokines, which can regulate the expression and function of each other. For example, IL9 can promote the production of IL4 and IL13, and IL4 and IL13 can also promote the secretion of IL9.

        What are the clinical applications of IL9? 09/26/2019

        IL9 can be used to treat certain inflammatory diseases, such as asthma and skin allergies. It can regulate the response of the immune system and reduce the symptoms of related diseases.

        What is the mechanism of action of IL9 in the treatment of asthma? 01/11/2019

        The mechanism of action of IL9 in asthma treatment is not fully understood, but studies have shown that it can reduce the infiltration of inflammatory cells and the release of inflammatory mediators, thereby reducing the symptoms of asthma.

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