IL9
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Official Full Name
interleukin 9
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Overview
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. -
Synonyms
IL9; interleukin 9; P40; HP40; IL-9; interleukin-9; cytokine P40; p40 cytokine; TTHUMP00000159423; T-cell growth factor p40; p40 T-cell and mast cell growth factor; homolog of mouse T cell and mast cell growth factor 40;
- Recombinant Proteins
- Cell & Tissue Lysates
- Antibody
- Transfected Stable Cell Lines
- GMP Proteins
- Protein Pre-coupled Magnetic Beads
- Arg19-Ile144
- Chicken
- Gln19-Pro144
- Human
- Mouse
- Rat
- Rhesus monkey
- C-His
- CHO
- E.coli
- HEK293
- HEK293F
- Hordeum Vulgare
- Human Cells
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Mouse
- Sf21 Insect Cell
- Wheat Germ
- Alexa Fluor 647
- Biotin
- C
- hFc
- His
- Flag
- Fc
- GST
- Avi
- T7
- HQ
- N
- SUMO
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
IL9 involved in several pathways and played different roles in them. We selected most pathways IL9 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Asthma, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | IL13RA1;BMPR2B;GM2506;IL24;CXCL14;IL1A;IL10RB;CCR1;EDA |
| Jak-STAT signaling pathway | IL22RA1;IRX1;AOX1;IFNA12;PIAS1;THPO;SOCS5;IL22;IFNA21 |
| Asthma | IL4;HLA-DQB1;HLA-DRB5;HLA-DRB4;FCER1G;IL9;HLA-DQA1;HLA-DRB3;IL13 |
IL9 has several biochemical functions, for example, cytokine activity, growth factor activity, interleukin-9 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL9 itself. We selected most functions IL9 had, and list some proteins which have the same functions with IL9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | IFNL3;INHBE;MSTN;GDF6B;IL29;FLT3LG;WNT7A;CMTM6;BMP5 |
| growth factor activity | FGF8A;GDF10;FGF21;FGF6B;CSF3;CECR1A;JAG1;PTN;TGFB1A |
| interleukin-9 receptor binding |
IL9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL9 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL9.
Gene Family
Research Area
Related articles
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewThe anti-interference ability of IL9 was excellent in Western blot, which avoided the interference problem in the experiment.
This protein has high catalytic efficiency, high safety and high expression level, and is a precious resource in the field of scientific research.
The reproducibility of IL9 is very good, which can reduce the error in the experiment and improve the repeatability of the experiment.
Q&As (6)
Ask a questionSeveral clinical trials are currently underway to evaluate the safety and effectiveness of IL9 in treating conditions such as asthma and allergies. However, the research is still in its early stages and more data are needed.
IL9 can be synthesized in the laboratory by biotechnological methods. Before clinical use, it needs to go through strict quality control and testing.
By binding to specific receptors, IL9 can activate relevant signaling pathways and regulate the development and function of immune cells. It can affect the activity of a variety of immune cells, such as T cells and macrophages.
IL9 has cross-action with other cytokines, which can regulate the expression and function of each other. For example, IL9 can promote the production of IL4 and IL13, and IL4 and IL13 can also promote the secretion of IL9.
IL9 can be used to treat certain inflammatory diseases, such as asthma and skin allergies. It can regulate the response of the immune system and reduce the symptoms of related diseases.
The mechanism of action of IL9 in asthma treatment is not fully understood, but studies have shown that it can reduce the infiltration of inflammatory cells and the release of inflammatory mediators, thereby reducing the symptoms of asthma.
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