CCL17 Protein

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CCL17

Official Full Name	chemokine (C-C motif) ligand 17
Background	This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
Synonyms	CCL17; A-152E5.3; ABCD-2; MGC138271; MGC138273; SCYA17; TARC; CC chemokine TARC; C-C motif chemokine; chemokine (C-C motif) ligand 17; small inducible cytokine subfamily A (Cys-Cys), member 17; Small-inducible cytokine A17; Thymus and activation-regulated chemokine

Species :
Chicken
Cynomolgus Monkey
Dog
Human
Mouse
Rat
Rhesus
Rhesus Macaque

Source :
Baculovirus-Insect Cells
E.coli
Human
Human Cell
Human Cells
Insect Cell
Mammalian Cell
Wheat Germ

Tag :
Biotin
DYKDDDDK
GST
His
His-KSI
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	Ccl17-463M	Active Recombinant Mouse Chemokine (C-C motif) Ligand 17	E.coli	N/A	Inquiry
Human	CCL17-0614H	Recombinant Human CCL17 Protein, GST-Tagged	Wheat Germ	GST	Inquiry
Human	CCL17-10839H	Recombinant Human CCL17, GST-tagged	E.coli	GST	Inquiry
Human	CCL17-192H	Recombinant Human CCL17, His tagged	Insect Cell	His	Inquiry
Human	CCL17-193H	Recombinant Human CCL17, None tagged	Insect Cell	N/A	Inquiry
Human	CCL17-24H	Recombinant Human CCL17 protein	E.coli	N/A	Inquiry
Human	CCL17-269H	Recombinant Human Chemokine (C-C motif) ligand 17, His-tagged	Human	His	Inquiry
Human	CCL17-30148TH	Recombinant Human CCL17	E.coli	N/A	Inquiry
Human	CCL17-30149TH	Recombinant Human CCL17, His-tagged	E.coli	His	Inquiry
Mouse	Ccl17-622M	Recombinant Mouse Ccl17 protein	E.coli	N/A	Inquiry
Mouse	Ccl17-625M	Recombinant Mouse Chemokine(C-C motif) Ligand 17	Human Cell	N/A	Inquiry
Mouse	Ccl17-7132M	Recombinant Mouse Ccl17 protein, His-tagged	E.coli	His	Inquiry
Mouse	Ccl17-832M	Recombinant Mouse Ccl17 Protein	Insect Cell	N/A	Inquiry
Rat	Ccl17-1346R	Recombinant Rat Ccl17 protein	E.coli	N/A	Inquiry
Rat	Ccl17-7133R	Recombinant Rat Ccl17 protein, His-tagged	E.coli	His	Inquiry
Cynomolgus Monkey	CCL17-8818C	Recombinant Cynomolgus CCL17, His tagged	Insect Cell	His	Inquiry
Rhesus Macaque	CCL17-680R	Recombinant Rhesus monkey CCL17 Protein, His-tagged	Mammalian Cell	His	Inquiry
Chicken	CCL17-5582C	Recombinant Chicken CCL17	Mammalian Cell	His	Inquiry
Human	CCL17-588HCL	Recombinant Human CCL17 cell lysate	Insect Cell	N/A	Inquiry
Mouse	CCL17-535MCL	Recombinant Mouse CCL17 cell lysate	Insect Cell	N/A	Inquiry
Cynomolgus Monkey	CCL17-001CCL	Recombinant Cynomolgus CCL17 cell lysate	Insect Cell	N/A	Inquiry
Human	CCL17-055C	Recombinant Human CCL17 Protein (71 aa)	E.coli		Inquiry
Human	CCL17-10H	Recombinant Human CCL17 Protein	E.coli		Inquiry
Dog	CCL17-1398D	Recombinant Dog CCL17 protein, His-KSI-tagged	E.coli	His-KSI	Inquiry
Human	CCL17-151H	Recombinant Human CCL17 Protein, DYKDDDDK-tagged	Human Cells	DYKDDDDK	Inquiry
Human	CCL17-41H	Recombinant Human CCL17 Protein	E.coli		Inquiry
Human	CCL17-55H	Recombinant Human CCL17 Protein, Biotin-tagged	E.coli	Biotin	Inquiry
Mouse	Ccl17-129M	Recombinant Mouse Ccl17 Protein	E.coli		Inquiry
Rhesus	CCL17-857R	Recombinant Rhesus CCL17 protein	E.coli	N/A	Inquiry
Rhesus	CCL17-858R	Recombinant Rhesus CCL17 protein, His-tagged	Baculovirus-Insect Cells	His	Inquiry

Involved Pathway Protein Function Interacting Protein CCL17 Related Articles CCL17 Related Gene Family

CCL17 involved in several pathways and played different roles in them. We selected most pathways CCL17 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cytokine-cytokine receptor interaction	IFNA21; PRL; IL18R1; PRLR; IFNL3; M17; CX3CL1; CXCL10; Flt3l; CCL20A.3
Chemokine signaling pathway	CCL18; XCL1; CCR9; SHC3; VAV3; PRKCZ; CXCR6; GNG2; XCR1; PTK2B

CCL17 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL17 itself. We selected most functions CCL17 had, and list some proteins which have the same functions with CCL17. You can find most of the proteins on our site.

Function	Related Protein
CCR chemokine receptor binding	CCL44; CCL24; CCL38.1; CCL19B; CCL35.1; CCL34B.1; CCL17; CCL20; CCL25B; CCL15
chemokine activity	CCL8; CCL19B; CCL13; CXCL20; CXCL2; CCL39.1; CCL11; XCL2; CCL34B.9; CXCL13
receptor binding	CADM1; ANG; CCL2; PTK2; SMARCD1; BLK; AGRP2; LIF; APOF; FGF8A

CCL17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL17 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL17.

Ma, T; Xu, JC; et al. Combination of C-X-C motif chemokine 9 and C-X-C motif chemokine 10 antibodies with FTY720 prolongs the survival of cardiac retransplantation allografts in a mouse model. EXPERIMENTAL AND THERAPEUTIC MEDICINE 9:1006-1012(2015).

Asquith, DL; Bryce, SA; et al. Targeting cell migration in rheumatoid arthritis. CURRENT OPINION IN RHEUMATOLOGY 27:204-211(2015).