ccl17
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  • Official Full Name
  • chemokine (C-C motif) ligand 17
  • Background
  • This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
  • Synonyms
  • CCL17; A-152E5.3; ABCD-2; MGC138271; MGC138273; SCYA17; TARC; CC chemokine TARC; C-C motif chemokine; chemokine (C-C motif) ligand 17; small inducible cytokine subfamily A (Cys-Cys), member 17; Small-inducible cytokine A17; Thymus and activation-regulated chemokine
Cat.#:CCL17-0614HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCL17 Protein, GST-Tagged
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Cat.#:Ccl17-1346RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ccl17 Protein
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Cat.#:CCL17-269HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chemokine (C-C motif) ligand 17, His-tagged
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Cat.#:Ccl17-463MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Chemokine (C-C motif) Ligand 17
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Cat.#:Ccl17-625MTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Chemokine(C-C motif) Ligand 17
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Cat.#:CCL17-10839HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL17, GST-tagged
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Cat.#:CCL17-192HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CCL17, His tagged
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Cat.#:CCL17-193HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CCL17, None tagged
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Cat.#:CCL17-30148THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL17
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Cat.#:CCL17-30149THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL17, His-tagged
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Cat.#:Ccl17-622MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ccl17
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Cat.#:Ccl17-7132MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ccl17 protein, His-tagged
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Cat.#:Ccl17-832MTag:
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Ccl17 Protein
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Cat.#:Ccl17-7133RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ccl17 protein, His-tagged
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Cat.#:CCL17-8818CTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CCL17, His tagged
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Cat.#:CCL17-680RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CCL17 Protein, His-tagged
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Cat.#:CCL17-5582CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CCL17
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Cat.#:CCL17-24HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chemokine (C-C Motif) Ligand 17
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Cat.#:CCL17-588HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human CCL17 cell lysate
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Cat.#:CCL17-535MCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse CCL17 cell lysate
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Cat.#:CCL17-001CCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CCL17 cell lysate
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Involved Pathway

CCL17 involved in several pathways and played different roles in them. We selected most pathways CCL17 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
CSF1RA; LEPB; TNFRSF11B; IFNB1; FLT3LG; XCL2; CCL23; IL12A; CCL14; TNFRSF8
Chemokine signaling pathway
Ccl27a; AMCF-II; SRC; GRK1; RAC2; DOCK2; ADRBK1; PLCB1; PAK1; CCL24

Protein Function

CCL17 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL17 itself. We selected most functions CCL17 had, and list some proteins which have the same functions with CCL17. You can find most of the proteins on our site.
Function
Related Protein
Function CCR chemokine receptor binding
Related Protein CCL3L1; XCL1; CCL38A.5; CCL8; CCL34B.4; CCRL2; CCL21; CCL3L3; CCL15; CCL19B
Function chemokine activity
Related Protein CXCL3; CCL38.1; CXCL9; CCL17; C5; Ccl9; CCL33.2; CCL14; CCL15; CCL38A.4
Function receptor binding
Related Protein ARRB2; CRTAM; LAMA3; LBP; PLXNC1; Fgf15; Ifnl2; CSK; HAO1; P2RX7

CCL17 Related Articles

Ma, T; Xu, JC; et al. Combination of C-X-C motif chemokine 9 and C-X-C motif chemokine 10 antibodies with FTY720 prolongs the survival of cardiac retransplantation allografts in a mouse model. EXPERIMENTAL AND THERAPEUTIC MEDICINE 9:1006-1012(2015).
Asquith, DL; Bryce, SA; et al. Targeting cell migration in rheumatoid arthritis. CURRENT OPINION IN RHEUMATOLOGY 27:204-211(2015).

CCL17 Related Gene Family

Chemokines Cytokines