CCL17

  • Official Full Name

    chemokine (C-C motif) ligand 17

  • Overview

    This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
  • Synonyms

    CCL17; A-152E5.3; ABCD-2; MGC138271; MGC138273; SCYA17; TARC; CC chemokine TARC; C-C motif chemokine; chemokine (C-C motif) ligand 17; small inducible cytokine subfamily A (Cys-Cys), member 17; Small-inducible cytokine A17; Thymus and activation-regulated chemokine;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Dog
  • Human
  • Mouse
  • Rat
  • Rhesus
  • Rhesus Macaque
  • Baculovirus-Insect Cells
  • E.coli
  • HEK293
  • Human
  • Human Cell
  • Human Cells
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • Biotin
  • C
  • His
  • DYKDDDDK
  • GST
  • His (Fc)
  • Avi
  • KSI
  • N/A
  • N
  • MBP
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCL17-192H Recombinant Human CCL17 protein Insect Cells N/A Met1-Ser94
Human CCL17-0614H Recombinant Human CCL17 Protein, GST-Tagged Wheat Germ GST
Human CCL17-30148TH Recombinant Human CCL17 E.coli N/A
Human CCL17-10839H Recombinant Human CCL17, GST-tagged E.coli GST 23-94a.a.
Human CCL17-30149TH Recombinant Human CCL17, His-tagged E.coli His
Human CCL17-269H Recombinant Human Chemokine (C-C motif) ligand 17, His-tagged Human His
Human CCL17-24H Recombinant Human CCL17 protein E.coli N/A 71
Human CCL17-193H Recombinant Human CCL17, None tagged Insect Cell N/A
Human CCL17-588HCL Recombinant Human CCL17 cell lysate Insect Cell N/A
Human CCL17-151H Recombinant Human CCL17 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human CCL17-10H Recombinant Human CCL17 Protein E.coli
Human CCL17-41H Recombinant Human CCL17 Protein E.coli 71 amino acid
Human CCL17-055C Active Recombinant Human CCL17 Protein (71 aa) E.coli 71
Human CCL17-1471H Recombinant Human CCL17 Protein (Ala24-Ser94), N-GST tagged E.coli N-GST Ala24-Ser94
Human CCL17-55H Recombinant Human CCL17 Protein, Biotin-tagged E.coli Biotin
Human CCL17-0265H Recombinant Human CCL17 protein, His-tagged Insect Cells His Met1-Ser94
Mouse Ccl17-463M Active Recombinant Mouse Chemokine (C-C motif) Ligand 17 E.coli N/A
Mouse Ccl17-625M Recombinant Mouse Chemokine(C-C motif) Ligand 17 Human Cell N/A 73aa
Mouse Ccl17-7132M Recombinant Mouse Ccl17 protein, His-tagged E.coli His Leu12~Lys83 (Accession # Q9WUZ6)
Mouse Ccl17-622M Recombinant Mouse Ccl17 protein E.coli N/A 70
Mouse Ccl17-832M Recombinant Mouse Ccl17 Protein Insect Cell N/A
Mouse CCL17-535MCL Recombinant Mouse CCL17 cell lysate Insect Cell N/A
Mouse Ccl17-129M Active Recombinant Mouse Ccl17 Protein E.coli
Rat Ccl17-7133R Recombinant Rat Ccl17 protein, His-tagged E.coli His Thr27~Leu93 (Accession # Q9ERE0)
Rat Ccl17-1346R Recombinant Rat Ccl17 protein E.coli N/A 70
Dog CCL17-3632D Recombinant Dog CCL17 protein, His-tagged Yeast C-His 24-99aa
Dog CCL17-6432D Recombinant Dog CCL17 protein(24-99aa), MBP&His-Avi-tagged, Biotinylated E.coli N-MBP&C-His-Avi 24-99aa
Dog CCL17-1398D Recombinant Dog CCL17 protein, His-KSI-tagged E.coli His-KSI 24-99aa
Dog CCL17-4930D Recombinant Dog CCL17 protein(24-99aa), His-tagged HEK293 C-His 24-99aa
Cynomolgus Monkey CCL17-8818C Recombinant Cynomolgus CCL17, His tagged Insect Cell His
Cynomolgus Monkey CCL17-001CCL Recombinant Cynomolgus CCL17 cell lysate Insect Cell N/A
Rhesus CCL17-857R Recombinant Rhesus CCL17 protein E.coli N/A 71
Rhesus CCL17-8818R Recombinant Rhesus CCL17, His tagged Insect Cell His Met1-Ser94
Rhesus CCL17-858R Active Recombinant Rhesus CCL17 protein, His-tagged Baculovirus-Insect Cells His Met1-Ser94
Rhesus Macaque CCL17-680R Recombinant Rhesus monkey CCL17 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CCL17-508R-B Recombinant Rhesus Macaque CCL17 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CCL17-508R Recombinant Rhesus Macaque CCL17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken CCL17-5582C Recombinant Chicken CCL17 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CCL17 involved in several pathways and played different roles in them. We selected most pathways CCL17 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL15RA;IFNA14;IL7R;CCL16;IL2RG;Ifna11;LTA;LIFR;PDGFAB
Chemokine signaling pathwayGNG12;GSK3B;Ccl21c;CXCR6;GNAI3;CXCR1;CCL22;ADRBK2;RLN1

CCL17 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL17 itself. We selected most functions CCL17 had, and list some proteins which have the same functions with CCL17. You can find most of the proteins on our site.

Function Related Protein
CCR chemokine receptor bindingCCL11;CCL34A.4;CCL21;CCL18;CCL19;CCL3L3;CCL19A.2;XCL1;CCL22
chemokine activityCCL8;CXCL13;CX3CL1;CCL19A.2;CCL27B;CXCL32B.1;Cxcl15;CCL27;CXCL3
receptor bindingPECR;FYB;PTK2BB;PAOX;ARPP19A;PCSK1N;MIF;BLK;PTPRD

CCL17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL17 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL17.

Gene Family

Chemokines Cytokines

Research Area

Related articles

Ma, T; Xu, JC; et al. Combination of C-X-C motif chemokine 9 and C-X-C motif chemokine 10 antibodies with FTY720 prolongs the survival of cardiac retransplantation allografts in a mouse model. EXPERIMENTAL AND THERAPEUTIC MEDICINE 9:1006-1012(2015).
Asquith, DL; Bryce, SA; et al. Targeting cell migration in rheumatoid arthritis. CURRENT OPINION IN RHEUMATOLOGY 27:204-211(2015).
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