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Official Full Name chemokine (C-C motif) ligand 17
Background This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
Synonyms CCL17; A-152E5.3; ABCD-2; MGC138271; MGC138273; SCYA17; TARC; CC chemokine TARC; C-C motif chemokine; chemokine (C-C motif) ligand 17; small inducible cytokine subfamily A (Cys-Cys), member 17; Small-inducible cytokine A17; Thymus and activation-regulated chemokine
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus
    • Rhesus Macaque
    • Source :
    • Baculovirus-Insect Cells
    • E.coli
    • Human
    • Human Cell
    • Human Cells
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCL17-151H Recombinant Human CCL17 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
    Human CCL17-0614H Recombinant Human CCL17 Protein, GST-Tagged Wheat Germ GST
    Human CCL17-10839H Recombinant Human CCL17, GST-tagged E.coli GST
    Human CCL17-192H Recombinant Human CCL17, His tagged Insect Cell His
    Human CCL17-193H Recombinant Human CCL17, None tagged Insect Cell N/A
    Human CCL17-24H Recombinant Human CCL17 protein E.coli N/A
    Human CCL17-269H Recombinant Human Chemokine (C-C motif) ligand 17, His-tagged Human His
    Human CCL17-30148TH Recombinant Human CCL17 E.coli N/A
    Human CCL17-30149TH Recombinant Human CCL17, His-tagged E.coli His
    Human CCL17-588HCL Recombinant Human CCL17 cell lysate Insect Cell N/A
    Mouse Ccl17-129M Recombinant Mouse Ccl17 Protein E.coli
    Mouse Ccl17-463M Recombinant Mouse Chemokine (C-C motif) Ligand 17 E.coli N/A
    Mouse CCL17-535MCL Recombinant Mouse CCL17 cell lysate Insect Cell N/A
    Mouse Ccl17-622M Recombinant Mouse Ccl17 protein E.coli N/A
    Mouse Ccl17-625M Recombinant Mouse Chemokine(C-C motif) Ligand 17 Human Cell N/A
    Mouse Ccl17-7132M Recombinant Mouse Ccl17 protein, His-tagged E.coli His
    Mouse Ccl17-832M Recombinant Mouse Ccl17 Protein Insect Cell N/A
    Rat Ccl17-1346R Recombinant Rat Ccl17 protein E.coli N/A
    Rat Ccl17-7133R Recombinant Rat Ccl17 protein, His-tagged E.coli His
    Cynomolgus Monkey CCL17-001CCL Recombinant Cynomolgus CCL17 cell lysate Insect Cell N/A
    Cynomolgus Monkey CCL17-8818C Recombinant Cynomolgus CCL17, His tagged Insect Cell His
    Rhesus Macaque CCL17-680R Recombinant Rhesus monkey CCL17 Protein, His-tagged Mammalian Cell His
    Rhesus CCL17-857R Recombinant Rhesus CCL17 protein E.coli N/A
    Rhesus CCL17-858R Recombinant Rhesus CCL17 protein, His-tagged Baculovirus-Insect Cells His
    Chicken CCL17-5582C Recombinant Chicken CCL17 Mammalian Cell His

    ccl17 involved in several pathways and played different roles in them. We selected most pathways ccl17 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ccl17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction TNFSF10; IL20RB; CD70; Ccl12; TNFRSF1A; CXCR5; IFN-a; BMPR1AA; KITLGB; TGFB2
    Chemokine signaling pathway STAT2; STAT3; CCL26; FGR; CCR7; ADRBK2; GNB4; GRK4; MAPK3; CXCL10

    ccl17 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ccl17 itself. We selected most functions ccl17 had, and list some proteins which have the same functions with ccl17. You can find most of the proteins on our site.

    Function Related Protein
    CCR chemokine receptor binding CCL24; CCL19; CCL38A.5; CCL44; CCL19A.1; CCL16; CCL34B.1; CCL13; CCL15; CCL26
    chemokine activity CCL17; CCL1; CXCL18B; CCL16; CCL34B.1; CXCL11.8; Ccl21c; CCL38A.4; CCL8; CCL2
    receptor binding MAG; GSDMA2; HSPA1B; DAO; BMP2; HRG; ANXA1; BMP3; PTK2AA; CSK

    ccl17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ccl17 here. Most of them are supplied by our site. Hope this information will be useful for your research of ccl17.

    Ma, T; Xu, JC; et al. Combination of C-X-C motif chemokine 9 and C-X-C motif chemokine 10 antibodies with FTY720 prolongs the survival of cardiac retransplantation allografts in a mouse model. EXPERIMENTAL AND THERAPEUTIC MEDICINE 9:1006-1012(2015).
    Asquith, DL; Bryce, SA; et al. Targeting cell migration in rheumatoid arthritis. CURRENT OPINION IN RHEUMATOLOGY 27:204-211(2015).

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