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Official Full Name chemokine (C-X-C motif) ligand 10
Background This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Jul 2008]
Synonyms CXCL10; chemokine (C-X-C motif) ligand 10; C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10; C-X-C motif chemokine 10; gamma IP10; gamma-IP10; small-inducible cytokine B10; interferon-inducible cytokine IP-10; 10 kDa interferon gamma-induced protein; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10;
    • Species :
    • Bovine
    • Canine
    • Caprine
    • Cattle
    • Cotton Rat
    • Dog
    • Dolphin
    • Equine
    • Feline
    • Guinea Pig
    • Human
    • Mouse
    • Ovine
    • Pig
    • Rat
    • Rhesus
    • Rhesus Macaque
    • Rhesus monkey
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • C-Myc/DDK
    • Fc
    • His
    • GST
    • HIS
    • Met
    • MYC/DDK
    • N/A
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CXCL10-01H Recombinant Human CXCL10 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human CXCL10-050H Recombinant Human CXCL10 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Mouse Cxcl10-074M Recombinant Mouse Cxcl10 Protein E.coli
    Mouse Cxcl10-075M Recombinant Mouse Cxcl10 Protein E.coli
    Mouse Cxcl10-076M Recombinant Mouse Cxcl10 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rhesus CXCL10-65R Recombinant Rhesus CXCL10 protein E.coli N/A
    Mouse CXCL10-805M Recombinant Mouse CXCL10 Protein (Ile22-Pro98), His-tagged Yeast His
    Rat CXCL10-938R Recombinant Rat CXCL10 Protein (Ile22-Pro98), His-tagged Yeast His
    Human CXCL10-025H Recombinant Human CXCL10 Protein, Fc/His-tagged HEK293 Fc/His
    Human CXCL10-08H Recombinant Human CXCL10 protein E.coli N/A
    Human CXCL10-105H Human CXCL10 N/A
    Human CXCL10-11716H Recombinant Human CXCL10, GST-tagged E.coli GST
    Human CXCL10-187H Recombinant Human CXCL10 protein E.coli N/A
    Human CXCL10-211H Recombinant Human Chemokine (C-X-C Motif) Ligand 10, MIgG2a Fc-tagged CHO Fc
    Human CXCL10-212H Recombinant Human Chemokine (C-X-C Motif) Ligand 10, HIgG1 Fc-tagged, mutant CHO Fc
    Human CXCL10-2158H Recombinant Human CXCL10 Protein, GST-tagged Wheat Germ GST
    Human CXCL10-242H Recombinant Human Chemokine (C-X-C Motif) Ligand 10, HIgG1 Fc-tagged CHO Fc
    Human CXCL10-274H Recombinant Human CXCL10, StrepII-tagged Human Cell Strep II
    Human CXCL10-28451TH Recombinant Human CXCL10 E.coli N/A
    Human CXCL10-29553TH Recombinant Human CXCL10, His-tagged E.coli His
    Human CXCL10-31H Recombinant Human CXCL10, His-tagged HEK293 His
    Human CXCL10-32H Recombinant Human Chemokine (C-X-C Motif) Ligand 10, His-tagged E.coli HIS
    Human CXCL10-524H Recombinant Human CXCL10 Protein, His-tagged E.coli His
    Human CXCL10-70H Recombinant Human CXCL10 (IP-10) Yeast N/A
    Human CXCL10-7172HCL Recombinant Human CXCL10 293 Cell Lysate HEK293 N/A
    Human CXCL10-7300H Recombinant Human CXCL10, None tagged E.coli N/A
    Human CXCL10-9H Human CXCL10 Reference Standard N/A
    Mouse Cxcl10-39M Recombinant Mouse Chemokine (C-X-C Motif) Ligand 10 E.coli N/A
    Mouse Cxcl10-525M Recombinant Mouse Cxcl10 Protein, His-tagged E.coli His
    Mouse Cxcl10-613M Recombinant Mouse Cxcl10 protein E.coli N/A
    Mouse CXCL10-71M Recombinant Mouse CXCL10 (IP-10) Yeast N/A
    Rat Cxcl10-121R Recombinant Rat Chemokine (C-X-C motif) Ligand 10 E.coli N/A
    Rat CXCL10-1687R Recombinant Rat CXCL10 Protein Mammalian Cell His
    Rat Cxcl10-526R Recombinant Rat Cxcl10 Protein, His-tagged E.coli His
    Rat Cxcl10-631R Recombinant Rat Cxcl10 protein E.coli N/A
    Rat CXCL10-86R Recombinant Rat CXCL10 Yeast N/A
    Rhesus Macaque CXCL10-1105R Recombinant Rhesus monkey CXCL10 Protein, His-tagged Mammalian Cell His
    Rhesus monkey CXCL10-1176R Recombinant Rhesus Monkey CXCL10 Protein E.coli N/A
    Dog CXCL10-523D Recombinant Dog CXCL10 Protein, His-tagged E.coli His
    Canine CXCL10-65C Recombinant Canine CXCL10 (IP-10) Yeast N/A
    Bovine CXCL10-133B Recombinant Bovine Chemokine (C-X-C motif) Ligand 10 Yeast N/A
    Equine CXCL10-142E Recombinant Equine Chemokine (C-X-C motif) Ligand 10 Yeast N/A
    Pig CXCL10-148S Recombinant Swine Chemokine (C-X-C motif) Ligand 10 Yeast N/A
    Cotton Rat Cxcl10-388C Recombinant Cotton Rat Cxcl10, Met-tagged E.coli Met
    Dolphin CXCL10-4341D Recombinant Dolphin CXCL10 Protein Yeast N/A
    Caprine CXCL10-4342C Recombinant Caprine CXCL10 Protein Yeast N/A
    Guinea Pig Cxcl10-4347G Recombinant Guinea Pig Cxcl10 Protein Yeast N/A
    Ovine CXCL10-50O Recombinant Ovine CXCL10 (IP-10) Yeast N/A
    Cattle CXCL10-522C Recombinant Cattle CXCL10 Protein, His-tagged E.coli His
    Feline CXCL10-69F Recombinant Feline CXCL10 (IP-10) Yeast N/A

    cxcl10 involved in several pathways and played different roles in them. We selected most pathways cxcl10 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Toll-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with cxcl10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction TGFBR1B; IL12BA; CCL21; PDGFRB; IL12RB1; IL5RA; CCL20B; CX3CL1; BMP2; PRP2
    Chemokine signaling pathway WASL; RAP1B; CCL13; CXCL11; PPBP; CCR6; CXCL8; CX3CL1; ARRB2; GNB1
    Toll-like receptor signaling pathway IRF5; CCL4L1; RAC1B; IKBKG; RAC1; MAPK12A; IFNA14; TLR5; PIK3R2; Ifna11
    RIG-I-like receptor signaling pathway CXCL8B.3; MAPK14B; IFNPHI3; DHX58; MAPK8B; ISG15; TRAF3; IKBKB; IL8L1; IFNA4
    Cytosolic DNA-sensing pathway POLR1C; NFKB1; IL33; IFNA6; IFNA3; CASP1; POLR3E; IL1B; IFNA7; DDX58
    TNF signaling pathway RPS6KA5; BCL3; CASP8; TNF; IKBKB; PIK3CB; DNM1L; NFKB1; CASP7; BIRC3

    cxcl10 has several biochemical functions, for example, CXCR3 chemokine receptor binding, cAMP-dependent protein kinase regulator activity, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cxcl10 itself. We selected most functions cxcl10 had, and list some proteins which have the same functions with cxcl10. You can find most of the proteins on our site.

    Function Related Protein
    CXCR3 chemokine receptor binding CXCL9; CXCL10; CXCL11.8; CXCL13; CXCL11; PF4
    cAMP-dependent protein kinase regulator activity PRKAR2AB; PRKAR1B; PRKAG2; PRKAR2A; PRKAR1AA; CXCL10; PRKAR1AB; PRKAG1; PRKAR1A; PRKAR2B
    chemokine activity CCL44; CCL39.1; CCL19B; XCL2; CCL34B.1; CCL3L1; CCL11; Ccl9; CCL3L3; CCL21B
    heparin binding ELANE; CCL8; SOST; Itgam&Itgb2; ANG; LPA; PTN; CTGFA; FGFRL1; ECM2
    protein binding DUSP14; PEX11B; CD24; TRIP10; GAS7; PHF7; AGO2; IPO7; ELK3; IFI6
    receptor binding Itga10&Itgb1; WNT2BA; TNFSF9; ADIPOQ; EPB49; ADAM10; LIF; FGF13B; FGF18B; HACL1

    cxcl10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cxcl10 here. Most of them are supplied by our site. Hope this information will be useful for your research of cxcl10.

    DPP4; DPP8

    Ma, T; Xu, JC; et al. Combination of C-X-C motif chemokine 9 and C-X-C motif chemokine 10 antibodies with FTY720 prolongs the survival of cardiac retransplantation allografts in a mouse model. EXPERIMENTAL AND THERAPEUTIC MEDICINE 9:1006-1012(2015).
    Asquith, DL; Bryce, SA; et al. Targeting cell migration in rheumatoid arthritis. CURRENT OPINION IN RHEUMATOLOGY 27:204-211(2015).

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