IL12
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Official Full Name
Interleukin 12
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Overview
Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation. -
Synonyms
Il12a; interleukin 12a; p35; Ll12a; Il-12a; IL-12p35; MGC151228; MGC151232; interleukin 12a p35 subunit; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); P35; CLMF; NFSK; NKSF1; IL-12A; natural killer cell stimulatory factor 1, 35 kD subunit; cytotoxic lymphocyte maturation factor 1, p35; interleukin;
- Recombinant Proteins
- GMP Proteins
- Transfected Stable Cell Lines
- Human
- Mouse
- Rat
- Baculovirus
- CHO
- CHO-K1
- HEK293
- HEK293 cells
- Insect cells
- Mammalian Cell
- Mammalian cells
- Yeast
- C
- Flag
- His
- Fc
- Avi
- Strep
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | IL12-002H | Active Recombinant Human IL12, HIgG1 Fc-tagged, mutant | CHO | Fc | ILe23-Ser328;Arg57-Ser253 |
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| Human | IL12-001H | Active Recombinant Human IL12, HIgG1 Fc-tagged | CHO | Fc | ILe23-Ser328;Arg57-Ser253 |
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| Human | IL12-160HG | Active GMP Recombinant Human IL12 Protein | HEK293 |
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| Human | IL12-01HG | Active GMP Recombinant Human IL12 Protein | CHO-K1 |
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| Human | IL12-4327H | Recombinant Human IL12A&IL12B heterodimer protein | CHO | Non | ||
| Human | IL12-417H | Active Recombinant Human IL12 protein | Yeast | Non |
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| Human | p40-P1008H | Recombinant Human IL-12/23 p40, Fc/His-tagged | CHO | His&Fc |
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| Human | IL12-159HB | Recombinant Human IL12 protein, His-tagged, Biotinylated | HEK293 | His | Met1-Ser219;Met1-Ser328 |
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| Human | IL12-158HG | Active GMP Recombinant Human IL12 Protein | HEK293 | Non | Arg23-Ser219;Ile23-Ser328 | |
| Human | IL12-3720H | Recombinant Human IL12 Protein (Arg23-Ser219, Ile23-Ser328), C-His and Strep tagged | Mammalian cells | His&Strep | Arg23-Ser219, Ile23-Ser328 |
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| Human | IL12-146H | Human Interleukin-12 (rDNA derived) Reference standard | Non |
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| Human | IL12-249H | Recombinant Human interleukin 12 Protein, His tagged | HEK293 | C-His | IL-12B: 23-328aa<br />IL-12A: 23-219aa |
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| Human | IL12-158H | Recombinant Human IL12 Protein | HEK293 | Non | Arg23-Ser219&Ile23-Ser328 |
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| Human | IL12-47H | Recombinant Human IL12 p40 (Ile23-Ser328) and p35 (Arg23-Ser219) Protein | Insect cells | p40 (Ile23-Ser328) and p35 (Arg23-Ser219) |
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| Human | IL12-159HG | Active GMP Recombinant Human IL12 protein | HEK293 | DNA sequence encoding Human p35 Subunit(UniProtKB/Swiss-Prot: P29459.2),p40 Subunit (NP_002178.2) was expressed with His tag at the C-terminal. |
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| Human | IL12-159H | Active Recombinant Human IL12 protein, His-tagged | HEK293 | His | IL12A: Met 1-Ser 219 <br />IL12B: Met 1-Ser 328 |
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| Human | IL12-22H | Recombinant Human Interleukin 12 Protein, His tagged | Baculovirus | C-His | 23-328aa(p40)/23-219aa(p35) |
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| Human | IL12-433H | Recombinant Human IL12 Protein, His-Avi-tagged | HEK293 | His&Avi | Ile23-Ser328 (IL12B/P40)/Arg23-Ser219(P35/IL12A) |
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| Human | IL12-0097H | Recombinant Human IL12 Protein | HEK293 cells |
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| Human | IL12-12H | Recombinant Human IL12 Protein, His-tagged | HEK293 | His | ||
| Mouse | IL12B&IL12A-004H | Active Recombinant Human IL12B&IL12A, HIgG1 Fc-tagged | CHO | Fc | ILe23-Ser328;Arg57-Ser253 |
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| Mouse | IL12-28M | Active Recombinant Mouse IL12 protein, His-tagged | Mammalian Cell | His | Met1-Ala215;Met1-Ser335 |
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| Mouse | IL12-002M | Active Recombinant Mouse IL12, HIgG1 Fc-tagged | CHO | Fc | 1-335;23-215 |
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| Mouse | IL12-001M | Active Recombinant Mouse IL12, HIgG1 Fc-tagged, mutant | CHO | Fc | ILe23-Ser328;Arg57-Ser253 |
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| Mouse | IL12-21M | Recombinant Mouse Interleukin 12 Protein, His tagged | Baculovirus | C-His | 23-335aa(p40)/23-215aa(p35) |
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| Mouse | Il12b-175M | Active Recombinant Mouse interleukin 12 Protein, Flag tagged | HEK293 | C-Flag | IL-12B: 23-335aa<br />IL-12A: 23-215aa |
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| Mouse | Il12-329M | Recombinant Mouse Il12, Fc-tagged | CHO | Fc | 1-335;23-215 |
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| Mouse | IL12-1031M | Active Recombinant Mouse IL12A & IL12B Heterotrimer Protein (Met1-Ala215 & Met1-Ser335), HlgG1 Fc-tagged | HEK293 | Fc | Met1-Ala215 & Met1-Ser335 |
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| Mouse | Il12-3765M | Recombinant Mouse Il12 Protein (Arg23-Ala215, Met23-Ser335), C-His and Strep tagged | Mammalian cells | His&Strep | Arg23-Ala215, Met23-Ser335 |
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| Rat | IL12-27R | Active Recombinant Rat IL12 protein, His-tagged | Mammalian Cell | His | Met23-Ser335;Arg23-Ser215 |
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| Rat | IL12-26R | Recombinant Rat IL12 protein, His-tagged | Mammalian Cell | His | Met23-Ser335;Arg23-Ser215 |
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| Rat | Il12-258I | Active Recombinant Rat Il12 Protein, His-tagged | CHO | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
- IL12 Related Signal Pathway
IL12 involved in several pathways and played different roles in them. We selected most pathways IL12 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | P2RY2;NPY1R;UTS2R;GABRA2;GRIN2BB;MCHR1;GRPR;TAAR7A;TAAR15 |
IL12 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by IL12 itself. We selected most functions IL12 had, and list some proteins which have the same functions with IL12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
IL12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL12 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL12.
Gene Family
Research Area
Related articles
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Customer Reviews (3)
Write a reviewEffective in Th1 cell differentiation.
High specificity in ELISA.
Stable under storage.
Q&As (10)
Ask a questionFluorescence microscopy tracks IL12 internalization and trafficking.
Phosphoproteomics and flow cytometry dissect IL12's signaling and crosstalk.
Flow cytometry and ELISA assess IL12's T cell subset polarization and cytokine profiles.
Reporter gene assays analyze IL12's promoter activity and response elements.
Super-resolution imaging details IL12's cellular distribution and dynamics.
3D cell culture models reveal IL12's effects on tissue microenvironments.
Co-localization studies and co-IP assays identify IL12's binding partners.
Techniques like co-immunoprecipitation reveal IL12 receptor complex assembly.
ChIP-seq helps map IL12-induced gene expression patterns and regulatory regions.
Transgenic models elucidate IL12's roles in immune response regulation.
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