IL10

  • Official Full Name

    interleukin 10

  • Overview

    factor involved in the inhibition of cytokine synthesis [RGD, Feb 2006]

  • Synonyms

    IL10;interleukin 10;IL10X;interleukin-10;CSIF;IL-10;cytokine synthesis inhibitory factor

Recombinant Proteins

  • Mouse
  • Human
  • Rhesus macaque
  • Monkey
  • Rat
  • Feline
  • Chicken
  • Cotton Rat
  • Pig
  • Porcine
  • Cynomolgus
  • Equine
  • Zebrafish
  • Bovine
  • Dog
  • Rabbit
  • Cattle
  • Horse
  • Rainbow trout
  • Ovine
  • Sheep
  • Goat
  • E.coli
  • HEK293
  • Yeast
  • CHO
  • Insect Cells
  • Mammalian Cells
  • Nicotiana Benthamiana
  • Human
  • Human Cells
  • Non
  • GST
  • His
  • Fc
  • Avi
  • Myc
  • T7
  • Flag
  • DDK
  • MBP
  • B2M
Cat.# Product name Source (Host) Species Tag Protein Length Price
Il10-642M Active Recombinant Mouse Il10 protein E.coli Mouse Non Ser19-Ser178
IL10-16H Recombinant Human IL10 protein E.coli Human Non 160
IL10-14140H Recombinant Human IL10, GST-tagged E.coli Human GST 19-178a.a.
Il10-17M Recombinant Mouse Il10 protein E.coli Mouse Non 160
IL10-21R Recombinant Rhesus monkey IL10 protein, His/GST-tagged E.coli Rhesus macaque GST&His 42-159 a.a.
IL10-372H Active Recombinant Human IL10 protein, His-tagged HEK293 Human His 19-178 a.a.
Il10-2566M Recombinant Mouse Il10 protein, His-tagged E.coli Mouse His 59-178 aa
Il10-3975M Recombinant Mouse Il10 protein, His-tagged E.coli Mouse His 19-119 aa
IL10-4400M Recombinant Monkey IL10 Protein Yeast Monkey Non 160aa
IL10-001M Active Recombinant Mouse IL10, MIgG2a Fc-tagged CHO Mouse Fc 1-178 a.a.
IL10-001R Active Recombinant Rat IL10, HIgG1 Fc-tagged CHO Rat Fc 19-178 a.a.
IL10-002M Active Recombinant Mouse IL10, MIgG2a Fc-tagged, mutant CHO Mouse Fc 1-178 a.a.
Il10-214M Active Recombinant Mouse Il10 protein E.coli Mouse Non 19-178 a.a.
IL10-215F Active Recombinant Feline IL10 E.coli Feline Non Ser19-Ile178
IL10-246C Active Recombinant Chicken Interleukin 10 Yeast Chicken Non
Il10-382C Active Recombinant Cotton Rat Il10 E.coli Cotton Rat Non 1-160 a.a.
IL10-507H Active Recombinant Human IL10 HEK293 Human Non 19-178 a.a.
IL10-566H Active Recombinant Human IL10, HIgG1 Fc-tagged CHO Human Fc 19-178 a.a.
IL10-569P Active Recombinant Pig IL10 protein E.coli Pig Non 19-175 a.a.
IL10-588H Active Recombinant Human IL10, HIgG1 Fc-tagged, mutant CHO Human Fc 19-178 a.a.
IL10-599H Active Recombinant Human IL10, MIgG2a Fc-tagged CHO Human Fc 19-178 a.a.
IL10-01P Active GMP Recombinant Porcine IL10 Protein, His-Tagged E.coli Porcine His
IL10-0292C Active Recombinant Cynomolgus IL10 protein, His-tagged HEK293 Cynomolgus His 19-178 a.a.
IL10-02H Active Recombinant Human IL10 Protein, His-Tagged Insect Cells Human His 166aa
IL10-6743H Recombinant Human IL10 protein, His-Avi-tagged, Biotinylated HEK293 Human Avi&His Ser19-Asn178
IL10-103E Recombinant Equine IL-10 Yeast Equine Non
IL10-1232C Recombinant Chicken IL10 Mammalian Cells Chicken His
IL10-1555H Recombinant human IL10, Active Nicotiana Benthamiana Human Non
il10-15Z Recombinant Zebrafish il10 protein Yeast Zebrafish Non
Il10-17S Recombinant Swine Il10 Yeast Pig Non
Il10-18R Recombinant Rat Il10 protein E.coli Rat Non 160
IL10-2228R Recombinant Rhesus monkey IL10 Protein, His-tagged Mammalian Cells Rhesus macaque His
IL10-22R Recombinant Rhesus macaque IL10 Protein, His-tagged Yeast Rhesus macaque His 19-178aa
IL10-23R Recombinant Rhesus macaque IL10 Protein, His/Myc-tagged Insect Cells Rhesus macaque His&Myc 19-178aa
IL10-2921Z Recombinant Zebrafish IL10 Mammalian Cells Zebrafish His
IL10-3023R Recombinant Rat IL10 Protein Mammalian Cells Rat His
IL10-3025H Recombinant Human Interleukin-10, T7-tagged E.coli Human T7
IL10-326H Active Recombinant Human IL10, Fc-tagged CHO Human Fc 19-178 a.a.
Il10-328M Active Recombinant Mouse Il10, Fc-tagged CHO Mouse Fc 1-178 a.a.
IL10-364H Recombinant Human Interleukin 10, His-tagged E.coli Human His
IL10-37B Recombinant Bovine IL-10 Yeast Bovine Non
IL10-40H Recombinant Human Interleukin 10 CHO Human Non
Il10-484R Recombinant Rat Il10 protein, His-tagged HEK293 Rat His Ser19~Asn178
IL10-492D Recombinant Dog IL10 protein, His-tagged HEK293 Dog His Ser20~IIe181
Il10-501M Recombinant Mouse Il10 protein, His-tagged HEK293 Mouse His 19-178 a.a.
IL10-513R Recombinant Rabbit IL10 protein, His-tagged HEK293 Rabbit His Ser19~Ser178
IL10-530H Recombinant Human Interleukin 10, His-tagged Human Human His
Il10-554R Recombinant Rat Il10 protein E.coli Rat Non Ser19-Asn178
IL10-79P Recombinant Porcine Interleukin 10 E.coli Pig Non
IL10-836C Recombinant Cattle IL10 protein, His & T7-tagged E.coli Cattle His&T7 Ser19~Lys178
IL10-837D Recombinant Dog IL10 protein, His & GST-tagged E.coli Dog GST&His Arg21~Ile181
IL10-838H Recombinant Horse IL10 protein, His & GST-tagged E.coli Horse GST&His Ser19~Asn178
IL10-839H Recombinant Human IL10 protein, His & T7-tagged E.coli Human His&T7 Ser19~Asn178
Il10-840M Recombinant Mouse Il10 protein, His & T7-tagged E.coli Mouse His&T7 Ser19~Ser178 linked with LEHHHHHH
Il10-841R Recombinant Rat Il10 protein, His & T7-tagged E.coli Rat His&T7 Ser19~Asn178
IL10-2079HCL Recombinant Human IL10 cell lysate Human Cells Human Non
Il10-040M Recombinant Mouse interleukin 10 Protein, His&Flag tagged HEK293 Mouse Flag&His 19-178aa
IL10-04HG Active Recombinant Human IL10 Protein (Ser19-Asn178), GMP Grade, Animal-Free E.coli Human Ser19-Asn178
Il10-082M Active Recombinant Mouse Il10 Protein E.coli Mouse
Il10-084M Recombinant Mouse Il10 Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc
IL10-115M Recombinant Mouse IL10 Protein E.coli Mouse Ser19-Ser178
Il10-128R Recombinant Rat interleukin 10 Protein, His&Flag tagged HEK293 Rat Flag&His 19-178aa
IL10-1297R Recombinant Rhesus macaque IL10 protein, Fc-tagged HEK293 Rhesus macaque Fc 19-178aa
IL10-135H Human Interleukin-10 (rDNA derived) Reference standard Human Non
Il10-135M Recombinant Active Mouse IL10 Protein, His-tagged(C-ter) E.coli Mouse His
IL10-136P Recombinant Active Pig IL10 Protein, His-tagged(C-ter) E.coli Pig His
IL10-13H Active Recombinant Human IL10 Protein, Pre-aliquoted Insect Cells Human Ser19-Asn178
Il10-1657R Recombinant Rat Il10 Protein, His-tagged E.coli Rat His Ser19-Asn178
IL10-174H Active Recombinant Human IL10 Protein (Ser19-Asn178), C-His tagged, Animal-free, Carrier-free E.coli Human His Ser19-Asn178
IL10-1761R Recombinant Rabbit IL10 protein, His-tagged E.coli Rabbit His Ser19~Ser178
IL10-2049R Recombinant Rhesus Macaque IL10 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
IL10-2049R-B Recombinant Rhesus Macaque IL10 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
IL10-204P Active Recombinant Pig IL10 Protein (Ser19-Asn175), C-His tagged, Animal-free, Carrier-free E.coli Pig His Ser19-Asn175
IL10-20R Recombinant Rhesus monkey IL10 protein, His-tagged E.coli Rhesus macaque His Ser19-Asn178
IL10-2232R Recombinant Rhesus macaque IL10 protein, C-terminal 10xHis-tagged-tagged Insect Cells Rhesus macaque His 19-178aa
IL10-2288C Recombinant Chicken IL10 Protein, His-tagged HEK293 Chicken His Leu22-Lys175
IL10-2322R Recombinant Rainbow trout IL10 protein, His&Myc-tagged E.coli Rainbow trout His&Myc 24-184aa
IL10-2460H Recombinant Human IL10 Protein (Ser19-Asn178), C-His tagged E.coli Human His Ser19-Asn178
IL10-2486H Recombinant Human IL10 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
IL10-24H Active Recombinant Human IL10 Protein, Animal Free Human Cells Human
Il10-260I Active Recombinant Rat Il10 Protein CHO Rat
Il10-261I Active Recombinant Mouse Il10 Protein CHO Mouse
IL10-2678R Recombinant Rat IL10 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
IL10-2678R-B Recombinant Rat IL10 Protein Pre-coupled Magnetic Beads HEK293 Rat
IL10-2697H Recombinant Human IL10 protein(19-178 aa), N-MBP & C-His-tagged HEK293 Human His&MBP 19-178 aa
IL10-301H Recombinant Human IL10 protein, His-Avi-tagged HEK293 Human Avi&His Ser19-Asn178
IL10-3090R Recombinant Rhesus macaque IL10 protein, His-B2M-tagged E.coli Rhesus macaque B2M&His 19-178aa
IL10-33O Recombinant Ovine IL10 Protein Yeast Ovine
IL10-3632R Recombinant Rainbow trout IL10 protein, His-tagged E.coli Rainbow trout His 24-184aa
Il10-371I Active Recombinant Rat Il10 Protein (161 aa) E.coli Rat 161
IL10-4325HG Active GMP Recombinant Human IL10 protein E.coli Human Non
IL10-4326HG Active GMP Recombinant Human IL10 protein HEK293 Human DNA sequence encoding Human IL-10(NP_000563.1) was expressed with His tag at the C-terminal.
Il10-45M Active Recombinant Mouse Il10 Protein (Ser19-Ser178), C-His tagged, Animal-free, Carrier-free E.coli Mouse His Ser19-Ser178
IL10-4644R Recombinant Rhesus macaque IL10 protein, DEEP1&His-tagged HEK293 Rhesus macaque His 19-178aa
IL10-46H Recombinant Human IL10 Protein E.coli Human Full L.
IL10-500M Recombinant Mouse IL10 Protein Mouse 178
IL10-5436B Recombinant Bovine IL10 protein, His-tagged Yeast Bovine His 19-178aa
IL10-5769S Recombinant Sheep IL10 protein, His-tagged Yeast Sheep His 20-177aa
Il10-6142M Recombinant Mouse Il10 protein, GST-tagged GST 19-178 aa
Il10-6143M Recombinant Mouse Il10 protein, His-tagged His 19-178 aa
IL10-994G Recombinant Goat IL10 Protein, His-tagged E.coli Goat His Ser17-Met174
Il10-995M Recombinant Mouse Il10 Protein, His-tagged HEK293 Mouse His Ser19-Ser178
IL10-996P Recombinant Pig IL10 Protein, His&GST-tagged E.coli Pig GST&His Ser19-Asn175
IL10-997C Recombinant Cattle IL10 Protein, His-tagged HEK293 Cattle His Ser19-Lys178
il10-998Z Recombinant Zebrafish il10 Protein, His-tagged E.coli Zebrafish His Arg23-His180
IL10-999C Recombinant Chicken IL10 Protein, His&GST-tagged E.coli Chicken GST&His Leu22-Lys175

    Involved Pathway

    IL10 involved in several pathways and played different roles in them. We selected most pathways IL10 participated on our site, such as African trypanosomiasis,Allograft Rejection,Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    African trypanosomiasis IL12A,HBB,PLCB2,HBA1,APOA1,TNF,IFNG,GNAQ,PRKCG,LAMA4
    Cytokine-cytokine receptor interaction CCL4L2,IL17B,KITA,VEGFC,PDGFC,KITLGB,IL7,CXCR3.1,CXCL8B.3,PDGFA
    Asthma HLA-DRB4,H2-AB1,CD40,HLA-DPB1,IL4,HLA-DRB3,EPX,CCL11,HLA-DRA,H2-AA
    Amoebiasis TGFB1,SERPINB3,SERPINB1A,GNA15,GNA14,FN1,RAB5C,COL4A1,PIK3CB,CD1d1
    Chagas disease (American trypanosomiasis) MAPK13,PPP2R1B,CCL5,RELA,CD247,BDKRB2,C1QC,MAPK10,FADD,FASLG
    Allograft rejection H2-AA,MICA,HLA-DRA,IL5,HLA-A,HLA-DRB3,HLA-C,H2-Q10,HLA-DPA1,GZMB
    Autoimmune thyroid disease OSTN,IFN-a,CGA,CTLA4

    Protein Function

    IL10 has several biochemical functions, for example, cytokine activity,growth factor activity,interleukin-10 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL10 itself. We selected most functions IL10 had, and list some proteins which have the same functions with IL10. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity NDP,CMTM1,INHBC,TNFSF10,IL13,AIMP1,GPI,TNFB,GM13288,GDF3
    growth factor activity BMP7,VHL,VEGFAA,NOV,IGF2A,NTF7,TGFB1A,GDF10B,FBRS,FGF1B

    Interacting Protein

    IL10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL10 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL10.

    IL10RA;A2M

    IL10 Related Signal Pathway

    Resources

    Gene Families

    References

    • Markwick, LJL; Riva, A; et al. Blockade of PD1 and TIM3 Restores Innate and Adaptive Immunity in Patients With Acute Alcoholic Hepatitis. GASTROENTEROLOGY 148:590-+(2015).
    • Shibahara, I; Saito, R; et al. OX40 ligand expressed in glioblastoma modulates adaptive immunity depending on the microenvironment: a clue for successful immunotherapy. MOLECULAR CANCER 14:-(2015).

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