IL10

  • Official Full Name

    interleukin 10

  • Overview

    factor involved in the inhibition of cytokine synthesis [RGD, Feb 2006]
  • Synonyms

    IL10; interleukin 10; IL10X; interleukin-10; CSIF; IL-10; cytokine synthesis inhibitory factor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • GMP Proteins
  • Transfected Stable Cell Lines
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Cattle
  • Chicken
  • Cotton Rat
  • Cynomolgus
  • Dog
  • Equine
  • Feline
  • Goat
  • Horse
  • Human
  • Monkey
  • Mouse
  • Ovine
  • Pig
  • Porcine
  • Rabbit
  • Rainbow trout
  • Rat
  • Rhesus macaque
  • Rhesus Macaque
  • Rhesus monkey
  • Sheep
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293F
  • HEK293T
  • Human
  • Human Cell
  • Human cells
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Nicotiana Benthamiana
  • Sf21 Insect Cell
  • Yeast
  • C
  • His
  • terminal 10xHis
  • tagged
  • Fc
  • GST
  • His (Fc)
  • Avi
  • His(C
  • ter)
  • His|GST
  • His|Myc
  • His|T7
  • B2M
  • Myc
  • DDK
  • MYC
  • N/A
  • N
  • MBP
  • Strep II
  • T7
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL10-599H Active Recombinant Human IL10, MIgG2a Fc-tagged CHO Fc
Human IL10-12H Active Recombinant Human IL10 E.coli N/A
Human IL10-566H Active Recombinant Human IL10, HIgG1 Fc-tagged CHO Fc
Human IL10-588H Active Recombinant Human IL10, HIgG1 Fc-tagged, mutant CHO Fc
Human IL10-478H Active Recombinant Human Interleukin 10 E.coli N/A
Human IL10-507H Active Recombinant Human IL10 HEK293 N/A
Human IL10-29629TH Active Recombinant Human IL10 protein E.coli N/A Ser 19-Asn 178
Human IL10-02H Active Recombinant Human IL10 Protein, His-Tagged Insect Cell His 166aa
Human IL10-16H Recombinant Human IL10 protein E.coli N/A 160
Human IL10-626H Recombinant Human Interleukin 10 HEK293 N/A
Human IL10-14140H Recombinant Human IL10, GST-tagged E.coli GST 19-178a.a.
Human IL10-217H Recombinant Human Interleukin 10 Sf21 Insect Cell N/A
Human IL10-3025H Recombinant Human Interleukin-10, T7-tagged E.coli T7
Human IL10-40H Recombinant Human Interleukin 10 CHO N/A
Human IL10-267H Recombinant Human IL10, StrepII-tagged Human Cell Strep II 19-178, 160 a.a.
Human IL10-28294TH Recombinant Human IL10 E.coli N/A
Human IL10-1555H Recombinant human IL10, Active Nicotiana Benthamiana N/A
Human IL10-372H Active Recombinant Human IL10 protein, His-tagged HEK293 His Ser19-Asn178
Human IL10-110H Recombinant Human Interleukin 10 HEK293 N/A
Human IL10-326H Active Recombinant Human IL10, Fc-tagged CHO Fc
Human IL10-364H Recombinant Human Interleukin 10, His-tagged E.coli His
Human IL10-28928TH Recombinant Human IL10, His-tagged E.coli His
Human IL10-839H Recombinant Human IL10 protein, His & T7-tagged E.coli His/T7 Ser19~Asn178 (Accession # P22301)
Human IL10-530H Recombinant Human Interleukin 10, His-tagged Human His
Human IL10-28293TH Recombinant Human IL10 N/A
Human IL10-2079HCL Recombinant Human IL10 cell lysate Human Cell N/A
Human IL10-4325HG Active GMP Recombinant Human IL10 protein E.coli N/A
Human IL10-2486H Recombinant Human IL10 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IL10-4326HG Active GMP Recombinant Human IL10 protein HEK293 DNA sequence encoding Human IL-10(NP_000563.1) was expressed with His tag at the C-terminal.
Human IL10-135H Human Interleukin-10 (rDNA derived) Reference standard N/A
Human IL10-301H Recombinant Human IL10 protein, His-Avi-tagged HEK293 His-Avi Ser19-Asn178
Human IL10-22HG Active Recombinant Human IL10 Protein (Ser19-Asn178), GMP Grade, Animal-Free E.coli Ser19-Asn178
Human IL10-060H Active Recombinant Human IL10 Protein E.coli
Human IL10-2033H Recombinant Human IL10 Protein, His-tagged HEK293 His Ser19-Asn178
Human IL10-04HG Active Recombinant Human IL10 Protein (Ser19-Asn178), GMP Grade, Animal-Free E.coli Ser19-Asn178
Human IL10-13H Active Recombinant Human IL10 Protein, Pre-aliquoted Insect Cell Ser19-Asn178
Human IL10-46H Recombinant Human IL10 Protein E.coli
Human IL10-24H Active Recombinant Human IL10 Protein, Animal Free Human cells
Human IL10-0021H Recombinant Human IL10 Protein HEK293 cells
Human IL10-499H Recombinant Human IL10 Protein 178
Human IL10-134H Recombinant Active Human IL10 Protein, His-tagged(C-ter) E.coli His(C-ter)
Human IL10-2460H Recombinant Human IL10 Protein (Ser19-Asn178), C-His tagged E.coli C-His Ser19-Asn178
Human IL10-127H Active Recombinant Human IL10 Protein E.coli
Human IL10-4294H Recombinant Human IL10 Protein (Ser19-Asn178), C-His tagged Mammalian cells C-His Ser19-Asn178
Human IL10-93H Recombinant Human IL10 Protein Human Cell
Human IL10-262I Active Recombinant Human IL10 Protein CHO
Human IL10-2627H Active Recombinant Human IL10 protein, His-tagged HEK293 His Ser19-Asn178
Human IL10-255H Active Recombinant Human IL10 Protein E.coli Tag Free
Human IL10-174H Active Recombinant Human IL10 Protein (Ser19-Asn178), C-His tagged, Animal-free, Carrier-free E.coli C-His Ser19-Asn178
Human IL10-2697H Recombinant Human IL10 protein(19-178 aa), N-MBP & C-His-tagged HEK293 N-MBP & C-His 19-178 aa
Mouse Il10-214M Active Recombinant Mouse Il10 protein E.coli N/A
Mouse Il10-642M Active Recombinant Mouse Il10 protein E.coli N/A Ser19-Ser178
Mouse IL10-001M Active Recombinant Mouse IL10, MIgG2a Fc-tagged CHO Fc
Mouse IL10-002M Active Recombinant Mouse IL10, MIgG2a Fc-tagged, mutant CHO Fc
Mouse Il10-01M Active Recombinant Mouse Il10 Protein, His-Tagged E.coli His
Mouse Il10-17M Recombinant Mouse Il10 protein E.coli N/A 160
Mouse Il10-501M Recombinant Mouse Il10 protein, His-tagged HEK293 His Ser19-Ser178
Mouse Il10-840M Recombinant Mouse Il10 protein, His & T7-tagged E.coli His/T7 Ser19~Ser178 linked with LEHHHHHH
Mouse Il10-328M Active Recombinant Mouse Il10, Fc-tagged CHO Fc
Mouse IL10-128M Active Recombinant Mouse IL10 Protein E.coli
Mouse Il10-2566M Recombinant Mouse Il10 protein, His-tagged E.coli His 59-178 aa
Mouse Il10-261I Active Recombinant Mouse Il10 Protein CHO
Mouse Il10-082M Active Recombinant Mouse Il10 Protein E.coli
Mouse IL10-115M Recombinant Mouse IL10 Protein E.coli Ser19-Ser178
Mouse Il10-45M Active Recombinant Mouse Il10 Protein (Ser19-Ser178), C-His tagged, Animal-free, Carrier-free E.coli C-His Ser19-Ser178
Mouse Il10-029I Active Recombinant Mouse Il10 Protein (161 aa) E.coli 161
Mouse Il10-083M Active Recombinant Mouse Il10 Protein E.coli
Mouse Il10-135M Recombinant Active Mouse IL10 Protein, His-tagged(C-ter) E.coli His(C-ter)
Mouse Il10-084M Recombinant Mouse Il10 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Il10-995M Recombinant Mouse Il10 Protein, His-tagged HEK293F N-His Ser19-Ser178
Mouse IL10-500M Recombinant Mouse IL10 Protein 178
Mouse Il10-3975M Recombinant Mouse Il10 protein, His-tagged E.coli His 19-119 aa
Rat IL10-001R Active Recombinant Rat IL10, HIgG1 Fc-tagged CHO Fc
Rat Il10-554R Recombinant Rat Il10 protein E.coli N/A Ser19-Asn178
Rat Il10-484R Recombinant Rat Il10 protein, His-tagged HEK293F His Ser19~Asn178
Rat Il10-841R Recombinant Rat Il10 protein, His & T7-tagged E.coli His/T7 Ser19~Asn178 (Accession # P29456)
Rat Il10-18R Recombinant Rat Il10 protein E.coli N/A 160
Rat IL10-3023R Recombinant Rat IL10 Protein Mammalian Cell His
Rat Il10-006I Active Recombinant Rat Il10 Protein (160 aa) E.coli 160
Rat Il10-1657R Recombinant Rat Il10 Protein, His-tagged E.coli N-His Ser19-Asn178
Rat Il10-260I Active Recombinant Rat Il10 Protein CHO
Rat IL10-129R Recombinant Rat IL10 Protein E.coli
Rat IL10-2678R-B Recombinant Rat IL10 Protein Pre-coupled Magnetic Beads HEK293
Rat Il10-371I Active Recombinant Rat Il10 Protein (161 aa) E.coli 161
Rat IL10-2678R Recombinant Rat IL10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Monkey IL10-4400M Recombinant Monkey IL10 Protein Yeast N/A 160aa
Rhesus monkey IL10-21R Recombinant Rhesus monkey IL10 protein, His/GST-tagged E.coli His/GST
Rhesus monkey IL10-20R Recombinant Rhesus monkey IL10 protein, His-tagged E.coli His Ser19-Asn178
Rabbit IL10-513R Recombinant Rabbit IL10 protein, His-tagged HEK293F His Ser19~Ser178
Rabbit IL10-1761R Recombinant Rabbit IL10 protein, His-tagged E.coli His Ser19~Ser178
Dog IL10-837D Recombinant Dog IL10 protein, His & GST-tagged E.coli His/GST Arg21~Ile181 (Accession # P48411)
Dog IL10-492D Recombinant Dog IL10 protein, His-tagged HEK293F His Ser20~IIe181
Bovine IL10-37B Recombinant Bovine IL-10 Yeast N/A
Bovine IL10-5436B Recombinant Bovine IL10 protein, His-tagged Yeast His 19-178aa
Cattle IL10-836C Recombinant Cattle IL10 protein, His & T7-tagged E.coli His/T7 Ser19~Lys178 (Accession # P43480)
Cattle IL10-997C Recombinant Cattle IL10 Protein, His-tagged HEK293F N-His Ser19-Lys178
Cotton Rat Il10-382C Active Recombinant Cotton Rat Il10 E.coli N/A
Cynomolgus IL10-0292C Active Recombinant Cynomolgus IL10 protein, His-tagged HEK293 His Ser19-Asn178
Equine IL10-103E Recombinant Equine IL-10 Yeast N/A
Feline IL10-215F Active Recombinant Feline IL10 E.coli N/A Ser19-Ile178
Goat IL10-994G Recombinant Goat IL10 Protein, His-tagged E.coli N-His Ser17-Met174
Horse IL10-838H Recombinant Horse IL10 protein, His & GST-tagged E.coli His/GST Ser19~Asn178 (Accession # Q28374)
Ovine IL10-33O Recombinant Ovine IL10 Protein Yeast
Porcine IL10-01P Active GMP Recombinant Porcine IL10 Protein, His-Tagged E.coli His
Rainbow trout IL10-3632R Recombinant Rainbow trout IL10 protein, His-tagged E.coli N-His 24-184aa
Rainbow trout IL10-2322R Recombinant Rainbow trout IL10 protein, His&Myc-tagged E.coli N-His&C-Myc 24-184aa
Rhesus macaque IL10-22R Recombinant Rhesus macaque IL10 Protein, His-tagged Yeast His 19-178aa
Rhesus macaque IL10-23R Recombinant Rhesus macaque IL10 Protein, His/Myc-tagged Insect Cell His/Myc 19-178aa
Rhesus Macaque IL10-2228R Recombinant Rhesus monkey IL10 Protein, His-tagged Mammalian Cell His
Rhesus Macaque IL10-2049R-B Recombinant Rhesus Macaque IL10 Protein Pre-coupled Magnetic Beads HEK293
Rhesus macaque IL10-1297R Recombinant Rhesus macaque IL10 protein, Fc-tagged HEK293 Fc 19-178aa
Rhesus macaque IL10-2232R Recombinant Rhesus macaque IL10 protein, C-terminal 10xHis-tagged-tagged Insect Cell C-terminal 10xHis-tagged 19-178aa
Rhesus Macaque IL10-2049R Recombinant Rhesus Macaque IL10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus macaque IL10-3090R Recombinant Rhesus macaque IL10 protein, His-B2M-tagged E.coli His-B2M 19-178aa
Sheep IL10-5769S Recombinant Sheep IL10 protein, His-tagged Yeast His 20-177aa
Zebrafish il10-15Z Recombinant Zebrafish il10 protein Yeast N/A
Zebrafish IL10-2921Z Recombinant Zebrafish IL10 Mammalian Cell His
Zebrafish il10-998Z Recombinant Zebrafish il10 Protein, His-tagged E.coli N-His Arg23-His180
Pig IL10-569P Active Recombinant Pig IL10 protein E.coli N/A Ser19-Asn175
Pig IL10-79P Recombinant Porcine Interleukin 10 E.coli N/A
Pig Il10-17S Recombinant Swine Il10 Yeast N/A
Pig IL10-136P Recombinant Active Pig IL10 Protein, His-tagged(C-ter) E.coli His(C-ter)
Pig IL10-204P Active Recombinant Pig IL10 Protein (Ser19-Asn175), C-His tagged, Animal-free, Carrier-free E.coli C-His Ser19-Asn175
Pig IL10-996P Recombinant Pig IL10 Protein, His&GST-tagged E.coli N-His&GST Ser19-Asn175
Chicken IL10-246C Active Recombinant Chicken Interleukin 10 Yeast N/A
Chicken IL10-1232C Recombinant Chicken IL10 Mammalian Cell His
Chicken IL10-2288C Recombinant Chicken IL10 Protein, His-tagged HEK293F N-His Leu22-Lys175
Chicken IL10-999C Recombinant Chicken IL10 Protein, His&GST-tagged E.coli N-His&GST Leu22-Lys175
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • IL10 Related Signal Pathway

IL10 involved in several pathways and played different roles in them. We selected most pathways IL10 participated on our site, such as African trypanosomiasis, Allograft Rejection, Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
African trypanosomiasisHBB-B1;IL6;VCAM1;PRKCG;MYD88;Fasl;F2RL1;HBB;IDO2
Allograft RejectionFasl;TNF;HLA-DRB4;HLA-C;IL4;FAS;HLA-DPB1;PRF1;HLA-DPA1
AmoebiasisIL6;RAB5B;TGFB3;C8G;LAMB4;PTK2;SERPINB1;GNAQ;COL4A1
AsthmaCD40LG;FCER1G;HLA-DQB1;H2-AB1;HLA-DMA;IL3;IL13;HLA-DPB1;IL9
Autoimmune thyroid diseaseOSTN;CGA;CTLA4;IFN-a;IL10
Chagas disease (American trypanosomiasis)TNFRSF1A;CASP8;GNAQ;IFNGR2;PPP2R2B;GNAI2;Il2;AKT2;IL1B
Cytokine-cytokine receptor interactionCCL28;IL26;GM-CSF;IL12RB1;PRL;CCL3;TNFRSF1B;CCR3;PF4

IL10 has several biochemical functions, for example, cytokine activity, growth factor activity, interleukin-10 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL10 itself. We selected most functions IL10 had, and list some proteins which have the same functions with IL10. You can find most of the proteins on our site.

Function Related Protein
cytokine activityVSTM1;GDF6B;IL17A/F3;FAM3D;EDN1;Ifna11;SLURP1;IL17F;GPI1
growth factor activityMDKB;GDF10B;BMP7;EFEMP1;MDK;FGF1A;LFT1;BMP2;GFER
interleukin-10 receptor binding

IL10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL10 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL10.

IL10RA; A2M

Gene Family

IL Cytokines

Research Area

Related articles

Markwick, LJL; Riva, A; et al. Blockade of PD1 and TIM3 Restores Innate and Adaptive Immunity in Patients With Acute Alcoholic Hepatitis. GASTROENTEROLOGY 148:590-+(2015).
Shibahara, I; Saito, R; et al. OX40 ligand expressed in glioblastoma modulates adaptive immunity depending on the microenvironment: a clue for successful immunotherapy. MOLECULAR CANCER 14:-(2015).
  • Reviews
  • Q&As

Customer Reviews (3)

Write a review
Reviews
09/27/2022

    Effective in anti-inflammatory assays.

    01/09/2019

      High purity levels.

      04/15/2017

        Stable under long-term storage.

        Q&As (10)

        Ask a question
        What state-of-the-art experimental strategies, including advanced imaging techniques, are implemented to meticulously assess the in vivo efficacy of IL-10-based therapies across a spectrum of inflammatory disorders? 02/12/2022

        Cutting-edge imaging techniques, alongside in vivo disease models, allow for precise assessment of therapeutic effects and tissue responses to IL-10-based treatments.

        How are advanced methods like single-cell RNA sequencing and flow cytometry harnessed to investigate the immunomodulatory impact of IL-10 across distinct immune cell subtypes? 02/10/2022

        Advanced technologies, including single-cell RNA sequencing and flow cytometry, enable a granular analysis of IL-10's impact on diverse immune cell subpopulations.

        Could you elaborate on the intricate experimental methodologies applied to unravel the influence of genetic polymorphisms within IL-10 and its receptor on disease susceptibility? 10/26/2021

        Genotyping studies and genetic association analyses help correlate variations in IL-10 and its receptor with disease susceptibility across diverse populations.

        How do researchers leverage advanced immunomonitoring tools to comprehensively evaluate the safety profiles of IL-10-based interventions in various clinical trial phases? 05/25/2021

        Advanced immunomonitoring tools, including multiplex cytokine assays and immune cell phenotyping, provide comprehensive safety evaluations of IL-10 interventions in clinical trials.

        How do researchers employ in vitro models to elucidate the mechanisms underlying IL-10's anti-inflammatory effects on immune cells? 12/03/2020

        In vitro models involve exposing immune cells to IL-10 and assessing changes in cytokine secretion and cell activation markers to uncover its anti-inflammatory mechanisms.

        What sophisticated experimental techniques are utilized to dissect the intricate signaling pathways downstream of IL-10 activation? 08/26/2020

        State-of-the-art techniques such as phosphoproteomics, mass spectrometry, and protein-protein interaction assays provide insights into the intricate signaling cascades activated by IL-10.

        Could you explain the multifaceted experimental strategies employed to determine the optimal dosage and administration routes for IL-10 in diverse animal models? 03/24/2019

        Dose-response studies in animal models coupled with outcome measures like cytokine profiles and immune cell phenotypes help determine the optimal IL-10 dosage and administration routes.

        What innovative experimental designs are employed to explore potential synergies between IL-10 and other cytokines, unraveling complex interplay in immune regulation? 11/23/2018

        Experimental designs encompass co-stimulation experiments, coupled with functional assays and high-dimensional analysis, to elucidate synergistic effects involving IL-10 and other cytokines.

        Can you elaborate on the comprehensive approaches scientists use to assess the tissue-specific expression patterns of IL-10 receptors in both normal and pathological conditions? 11/05/2018

        Techniques like RT-PCR, immunohistochemistry, and spatial transcriptomics are employed to characterize IL-10 receptor expression patterns in specific tissues and disease contexts.

        How are cutting-edge techniques such as CRISPR/Cas9 gene editing utilized to dissect the regulatory roles of IL-10 in complex autoimmune disease models? 02/22/2018

        CRISPR/Cas9 gene editing is used to create knockout or overexpression models, combined with functional assays, to decipher IL-10's regulatory roles in autoimmune disease pathways.

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