"VEGFA" Related Products

Recombinant Human Vascular Endothelial Growth Factor A

Cat. No. : VEGFA-5531H
Product Overview : Recombinant human VEGF165is expressed in human 293 cells as a homodimeric glycoprotein with anapparent molecular mass of 45 kDa.
Description : This gene is amember of the platelet-derived growth factor (PDGF)/vascular endothelialgrowth factor (VEGF) family and encodes a protein that is often found as adisulfide linked homodimer. This protein is a glycosylated mitogen thatspecifically acts on endothelial cells and has various effects.
Source : HEK 293 cells
Species : Human
Purity : >95% The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel wasstained with Coomassie blue.
Molecular Mass : 45 kDa, homodimer,glycosylated
Endotoxin Level : Endotoxin Free <1EU/μg
Biological Activity : 2 to 10 ng/mL ED50
Specific Activity : The specificactivity was determined by the dose-dependent stimulation of theproliferation of HUVEC cells (Human Umbilical Vein Endothelial Cells).
OfficialSymbol : VEGFA
Pathways : Bladder cancer;Cytokine-cytokine receptor interaction; Endochondral Ossification; Focaladhesion; Glypican 1 network; HIF-1-alpha transcription factor network;HIF-2-alpha transcription factor network; Heart Development; Hemostasis;Hypertrophy Model; Id Signaling Pathway; Integrins in angiogenesis;Neurophilin interactions with VEGF and VEGFR; Pancreatic cancer; Pathways incancer
PDB rendering basedon 1bj1. :

Gene Name : VEGFA vascular endothelialgrowth factor A [ Homo sapiens ]
Synonyms : VEGFA;vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascularendothelial growth factor A; OTTHUMP00000016487; OTTHUMP00000016488;OTTHUMP00000165985; OTTHUMP00000165986; OTTHUMP00000165987;OTTHUMP00000224107; OTTHUMP00000224108; OTTHUMP00000224109;OTTHUMP00000224153; OTTHUMP00000224154; OTTHUMP00000224423;OTTHUMP00000224424; OTTHUMP00000224425; OTTHUMP00000224426;OTTHUMP00000224427; OTTHUMP00000224428; OTTHUMP00000224429;OTTHUMP00000224430; vascular permeability factor; Vascular endothelial growth factor A; Vascular permeability factor
Gene ID : 7422
mRNA Refseq : NM_001025366
Protein Refseq : NP_001020537
MIM : 192240
UniProt ID : P15692
Chromosome Location : 6p12
Function : cell surfacebinding; chemoattractant activity; cytokine activity; extracellular matrixbinding; fibronectin binding; growth factor activity; heparin binding;platelet-derived growth factor receptor binding; protein binding; proteinheterodimerization activity; vascular endothelial growth factor receptor 1binding; vascular endothelial growth factor receptor 2 binding; vascularendothelial growth factor receptor binding

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