Recombinant Human Vascular Endothelial Growth Factor A

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Recombinant Human Vascular Endothelial Growth Factor A

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Cat. No. : VEGFA-5531H
Product Overview : Recombinant human VEGF165is expressed in human 293 cells as a homodimeric glycoprotein with anapparent molecular mass of 45 kDa.
Description : This gene is amember of the platelet-derived growth factor (PDGF)/vascular endothelialgrowth factor (VEGF) family and encodes a protein that is often found as adisulfide linked homodimer. This protein is a glycosylated mitogen thatspecifically acts on endothelial cells and has various effects.
Source : HEK 293 cells
Species : Human
Purity : >95% The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel wasstained with Coomassie blue.
Molecular Mass : 45 kDa, homodimer,glycosylated
Endotoxin Level : Endotoxin Free <1EU/μg
Biological Activity : 2 to 10 ng/mL ED50
Specific Activity : The specificactivity was determined by the dose-dependent stimulation of theproliferation of HUVEC cells (Human Umbilical Vein Endothelial Cells).
OfficialSymbol : VEGFA
Pathways : Bladder cancer;Cytokine-cytokine receptor interaction; Endochondral Ossification; Focaladhesion; Glypican 1 network; HIF-1-alpha transcription factor network;HIF-2-alpha transcription factor network; Heart Development; Hemostasis;Hypertrophy Model; Id Signaling Pathway; Integrins in angiogenesis;Neurophilin interactions with VEGF and VEGFR; Pancreatic cancer; Pathways incancer
Gene Name : VEGFA vascular endothelialgrowth factor A [ Homo sapiens ]
Synonyms : VEGFA;vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascularendothelial growth factor A; OTTHUMP00000016487; OTTHUMP00000016488;OTTHUMP00000165985; OTTHUMP00000165986; OTTHUMP00000165987;OTTHUMP00000224107; OTTHUMP00000224108; OTTHUMP00000224109;OTTHUMP00000224153; OTTHUMP00000224154; OTTHUMP00000224423;OTTHUMP00000224424; OTTHUMP00000224425; OTTHUMP00000224426;OTTHUMP00000224427; OTTHUMP00000224428; OTTHUMP00000224429;OTTHUMP00000224430; vascular permeability factor; Vascular endothelial growth factor A; Vascular permeability factor
Gene ID : 7422
mRNA Refseq : NM_001025366
Protein Refseq : NP_001020537
MIM : 192240
UniProt ID : P15692
Chromosome Location : 6p12
Function : cell surfacebinding; chemoattractant activity; cytokine activity; extracellular matrixbinding; fibronectin binding; growth factor activity; heparin binding;platelet-derived growth factor receptor binding; protein binding; proteinheterodimerization activity; vascular endothelial growth factor receptor 1binding; vascular endothelial growth factor receptor 2 binding; vascularendothelial growth factor receptor binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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