vegfa

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vegfa

Official Full Name vascular endothelial growth factor A
Background This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008]
Synonyms VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor; Vegf120; Vegf164; Vegf188
    • Species :
    • Bovine
    • Canine
    • Cattle
    • Chicken
    • Dog
    • Equine
    • Feline
    • Goat
    • Human
    • Mouse
    • Pig
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Rhesus monkey
    • Source :
    • Barley Grain
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • HEK293F
    • Human
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Nicotiana Benthamiana
    • NS0
    • NSO
    • P.pastoris
    • Sf21 Insect Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • Biotin
    • GST
    • His
    • Avi
    • S
    • T7
    • Met
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human VEGFA-22H Recombinant Human VEGFA Protein E. coli N/A
    Human VEGFA-001H Recombinant Human VEGFA Protein, His-tagged Insect Cell His
    Human VEGFA-274H Recombinant Human VEGFA Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
    Mouse VEGFA-377M Recombinant Mouse VEGF120 Protein, His & Avi-tagged, Biotinylated HEK293 His/Avi
    Mouse VEGFA-381M Recombinant Mouse VEGFA protein (HPLC-verified) HEK293
    Human VEGFA-382H Recombinant Human VEGFA protein, His-tagged HEK293 His
    Rat Vegfa-436R Recombinant Rat Vegfa protein Yeast N/A
    Human VEGFA-657H Recombinant Human VEGFA protein Yeast N/A
    Human VEGFA-700H Recombinant Human VEGFA Protein (Met1-Arg136) Insect Cell N/A
    Rat Vegfa-7862R Recombinant Rat protein Yeast N/A
    Mouse Vegfa-902M Recombinant Mouse Vegfa protein Yeast N/A
    Human VEGFA-938H Recombinant Human VEGFA protein Yeast N/A
    Mouse Vegfa-992M Recombinant Mouse Vegfa protein Yeast N/A
    Human VEGFA&PGF-399H Recombinant Human VEGFA&PGF E.coli N/A
    Human VEGFA&PIGF-28H Recombinant human VEGF/PlGF E.coli N/A
    Human VEGFA-060H Recombinant Human VEGFA Protein HEK293 N/A
    Human VEGFA-101H Recombinant Human VEGFA, His-tagged Barley Grain His
    Human VEGFA-102H Recombinant Human VEGFA, GST-tagged Wheat Germ GST
    Human VEGFA-102HG GMP Recombinant Human VEGFA Protein Insect Cell N/A
    Human VEGFA-130H Recombinant Human Vascular Endothelial Growth Factor 121, His-tagged E.coli His
    Human VEGFA-1427HCL Recombinant Human VEGFA cell lysate Human Cell N/A
    Human VEGFA-143H Recombinant Human VEGFA Protein P.pastoris N/A
    Human VEGFA-1569H Recombinant human VEGFA, Active, His-tagged Nicotiana Benthamiana His
    Human VEGFA-156H Recombinant Human VEGF165 HEK293 N/A
    Human VEGFA-1607H Recombinant Human VEGFA protein, His-tagged E.coli His
    Human VEGFA-167H Recombinant Human VEGFA protein, His/S-tagged E.coli His/S
    Human VEGFA-172H Recombinant Human VEGFA Protein, Biotinylated Insect Cell N/A
    Human VEGFA-17H Recombinant Human VEGFA protein E.coli N/A
    Human VEGFA-19H Recombinant Human VEGFA protein E.coli N/A
    Human VEGFA-210H Recombinant Human VEGFA, None tagged Insect Cell N/A
    Human VEGFA-25H Recombinant Human VEGF 162 NSO N/A
    Human VEGFA-271H Recombinant Human VEGFA, Biotinylated HEK293 N/A
    Human VEGFA-272H Recombinant Human VEGFA, Biotinylated HEK293 N/A
    Human VEGFA-273H Recombinant Human VEGFA Protein, His & Avi-tagged, Biotinylated HEK293 His/Avi
    Human VEGFA-309H Recombinant Human VEGFA protein HEK293 N/A
    Human VEGFA-31202TH Recombinant Human VEGFA, His-tagged His
    Human VEGFA-31560TH Recombinant Human VEGFA, His-tagged His
    Human VEGFA-31562TH Recombinant Human VEGFA E.coli N/A
    Human VEGFA-31563TH Recombinant Human VEGFA N/A
    Human VEGFA-31701TH Native Human VEGFA E.coli N/A
    Human VEGFA-31706TH Recombinant Human VEGFA, His-tagged E.coli His
    Human VEGFA-362H Recombinant Human VEGFA protein HEK293 N/A
    Human VEGFA-365H Recombinant Human Vascular Endothelial Growth Factor 165 P.pastoris N/A
    Human VEGFA-389H Recombinant Human Vascular Endothelial Growth Factor A 109 E.coli N/A
    Human VEGFA-390H Recombinant Human Vascular Endothelial Growth Factor A 115 E.coli N/A
    Human VEGFA-391H Recombinant Human VEGFA Mammalian Cell His
    Human VEGFA-407H Recombinant Human VEGFA protein, His-tagged HEK293 His
    Human VEGFA-425H Recombinant Human VEGFA, Met-tagged E.coli Met
    Human VEGFA-504H Recombinant Human VEGFA CHO N/A
    Human VEGFA-50H Recombinant Human Vascular Endothelial Growth Factor 165 CHO N/A
    Human VEGFA-521H Recombinant Human VEGFA HEK293 N/A
    Human VEGFA-522H Recombinant Human VEGFA protein HEK293
    Human VEGFA-543H Recombinant Human VEGFA Human His
    Human VEGFA-548H Recombinant Human VEGFA, None tagged Insect Cell N/A
    Human VEGFA-549H Recombinant Human VEGFA, None tagged Insect Cell N/A
    Human VEGFA-5529H Recombinant Human Vascular Endothelial Growth Factor A Sf9 Insect Cell N/A
    Human VEGFA-5530H Recombinant Human Vascular Endothelial Growth Factor A HEK293 N/A
    Human VEGFA-5531H Recombinant Human Vascular Endothelial Growth Factor A HEK293 N/A
    Human VEGFA-5532H Recombinant Human Vascular Endothelial Growth Factor A E.coli N/A
    Human VEGFA-583H Recombinant Human Vascular Endothelial Growth Factor A E.coli N/A
    Human VEGFA-584H Recombinant Human VEGFA protein, His-tagged E.coli His
    Human VEGFA-648H Recombinant Human VEGFA E.coli N/A
    Human VEGFA-649H Recombinant Human VEGFA, Met-tagged E.coli Met
    Human VEGFA-650H Recombinant Human neuropilin 2, His-tagged Insect Cell His
    Human VEGFA-655HCL Recombinant Human VEGFA cell lysate Insect Cell N/A
    Human VEGFA-703H Recombinant Human VEGFA Sf21 Insect Cell N/A
    Human VEGFA-709H Recombinant Human Vascular Endothelial Growth Factor A Insect Cell N/A
    Human VEGFA-710H Recombinant Human VEGFA, Met-tagged E.coli Met
    Human VEGFA-711H Recombinant Human VEGFA, Isoform 165, His-tagged, Biotinylated Human Cell His
    Human VEGFA-713H Recombinant Human Vascular Endothelial Growth Factor A, His-tagged E.coli His
    Human VEGFA-715H Recombinant Human Vascular Endothelial Growth Factor A Insect Cell N/A
    Human VEGFA-727HCL Recombinant Human VEGFA cell lysate Insect Cell N/A
    Human VEGFA-8213H Recombinant Human VEGFA, Biotin-tagged HEK293 Biotin
    Human VEGFA-868H Recombinant Human Vascular Endothelial Growth Factor A, His-tagged E.coli His
    Human VEGFA-8699H Recombinant Human VEGFA P.pastoris N/A
    Human VEGFA-86H Recombinant Human VEGFA protein (HPLC-verified) HEK293
    Human VEGFA-974HCL Recombinant Human VEGFA cell lysate Human Cell N/A
    Human VEGFA-P1003H Recombinant Human VEGFA CHO N/A
    Mouse Vegfa-1608M Recombinant Mouse Vegfa protein, His & T7-tagged E.coli His/T7
    Mouse Vegfa-166M Recombinant Mouse Vegfa protein, His/S-tagged E.coli His/S
    Mouse Vegfa-16M Recombinant Murine Vascular Endothelial Growth Factor 120 E.coli N/A
    Mouse Vegfa-172M Recombinant Mouse Vegfa Sf21 Insect Cell N/A
    Mouse Vegfa-18M Recombinant Mouse Vegfa protein P.pastoris N/A
    Mouse Vegfa-206M Recombinant Mouse Vegfa E.coli N/A
    Mouse Vegfa-26M Recombinant mouse VEGF 164 Sf21 Insect Cell N/A
    Mouse Vegfa-313M Recombinant Mouse Vascular Endothelial Growth Factor A E.coli N/A
    Mouse Vegfa-357M Recombinant Mouse Vascular Endothelial Growth Factor A Sf21 Insect Cell N/A
    Mouse Vegfa-36M Recombinant Mouse Vegfa, His-tagged Barley Grain His
    Mouse Vegfa-464M Recombinant Mouse Vascular Endothelial Growth Factor A 164AA E.coli N/A
    Mouse Vegfa-475M Recombinant Mouse Vegfa, None tagged Insect Cell N/A
    Mouse VEGFA-47M Recombinant Mouse VEGFA protein E.coli N/A
    Mouse VEGFA-51M Recombinant Mouse Vascular Endothelial Growth Factor 164 Sf9 Insect Cell N/A
    Mouse Vegfa-530M Recombinant Mouse Vegfa Sf9 Insect Cell N/A
    Mouse Vegfa-5533M Recombinant Mouse Vascular Endothelial Growth Factor A Sf9 Insect Cell N/A
    Mouse Vegfa-582M Recombinant Mouse Vascular Endothelial Growth Factor A E.coli N/A
    Mouse Vegfa-585M Recombinant Mouse Vegfa protein E.coli N/A
    Mouse VEGFA-647MCL Recombinant Mouse VEGFA cell lysate Insect Cell N/A
    Mouse Vegfa-720M Recombinant Mouse Vegfa protein HEK293
    Mouse Vegfa-725M Recombinant Mouse Vegfa, Isoform 120, His-tagged, Biotinylated Human Cell His
    Mouse Vegfa-726M Recombinant Mouse Vegfa, Isoform 120, His-tagged Human Cell His
    Mouse Vegfa-727M Recombinant Mouse Vegfa, Isoform 164, His-tagged, Biotinylated Human Cell His
    Mouse Vegfa-728M Recombinant Mouse Vegfa, Isoform 164, His-tagged Human Cell His
    Mouse Vegfa-729M Recombinant Mouse Vegfa Protein, His & Avi-tagged, Biotinylated HEK293 His/Avi
    Rat Vegfa-165R Recombinant Rat Vegfa protein, His/S-tagged E.coli His/S
    Rat Vegfa-27R Recombinant rat VEGF 164 NSO N/A
    Rat Vegfa-383R Recombinant Rat Vegfa NS0 N/A
    Rat Vegfa-44R Recombinant Rat Vegfa protein E.coli N/A
    Rat VEGFA-522RCL Recombinant Rat VEGFA cell lysate Insect Cell N/A
    Rat Vegfa-544R Recombinant Rat Vegfa protein, His-tagged HEK293F His
    Rat Vegfa-586R Recombinant Rat Vascular Endothelial Growth Factor-165 E.coli N/A
    Rat Vegfa-677R Recombinant Rat vascular endothelial growth factor A, His-tagged E.coli His
    Rat Vegfa-762R Recombinant Rat Vegfa P.pastoris N/A
    Rat Vegfa-878R Recombinant Rat Vegfa, None tagged Insect Cell N/A
    Rat Vegfa-9928R Recombinant Rat Vegfa CHO N/A
    Rhesus monkey VEGFA-1762R Recombinant Rhesus monkey VEGFA protein, His-tagged E.coli His
    Rhesus Macaque VEGFA-5152R Recombinant Rhesus monkey VEGFA Protein, His-tagged Mammalian Cell His
    Canine VEGFA -24D Recombinant Canine VEGF E.coli N/A
    Canine VEGFA-270C Recombinant Canine VEGFA E.coli N/A
    Canine VEGFA-302C Recombinant Canine VEGFA, None tagged Human Cell His
    Canine VEGFA-453C Recombinant Canine VEGFA protein Yeast N/A
    Dog VEGFA-591D Recombinant Dog VEGFA protein, His-tagged E.coli His
    Canine VEGFA-969CCL Recombinant Canine VEGFA cell lysate Human Cell N/A
    Bovine VEGFA-23B Recombinant Bovine VEGF-A Yeast N/A
    Bovine VEGFA-366B Recombinant Bovine Vascular Endothelial Growth Factor A Yeast N/A
    Chicken VEGFA-3771C Recombinant Chicken VEGFA Mammalian Cell His
    Chicken VEGFA-4373C Recombinant Chicken VEGFA Protein Yeast N/A
    Rabbit VEGFA-595R Recombinant Rabbit VEGFA protein, His & T7-tagged E.coli His/T7
    Rabbit VEGFA-99R Recombinant Rabbit VEGF-A Yeast N/A
    Equine VEGFA-209E Recombinant Equine VEGFA Yeast N/A
    Goat VEGFA-4326G Recombinant Goat VEGFA Protein Yeast N/A
    Feline VEGFA-54F Recombinant Feline VEGF-A Yeast N/A
    Cattle VEGFA-590C Recombinant Cattle VEGFA protein, His & T7-tagged E.coli His/T7
    Pig VEGFA-593P Recombinant Pig VEGFA protein, His & GST-tagged E.coli His/GST
    Feline VEGFA-637F Recombinant Feline VEGFA, Met-tagged E.coli Met

    vegfa involved in several pathways and played different roles in them. We selected most pathways vegfa participated on our site, such as Ras signaling pathway, Rap signaling pathway, Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with vegfa were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ras signaling pathway STK4; PLA2G5; PLA2G2A; SHC4; KRAS; GNG4; RALBP1; FGF12; PIK3CG; PIK3CB
    Rap signaling pathway PRKCA; LAT; FIGF; PIK3CD; LPAR3; KITLG; ITGAM; CDH1; FGFR2; ACTG1
    Cytokine-cytokine receptor interaction THPO; CXCL3; IL8L2; MET; CCL3; Il6ra; PDGFC; CXCR4; TNFSF15; IL10
    HIF- signaling pathway PLCG2; IL6R; ANGPT4; PIK3R5; RPS6; HK2; INS1; CAMK2G; PDK1; EP300
    mTOR signaling pathway DDIT4; RICTOR; RRN3; RPS6KA6; IRS1; POLDIP3; RPS6KB1; VEGFAA; VEGFAB; MAPK3
    PIK-Akt signaling pathway IL3RA; IL2RB; AKT1; ITGB5; RPS6KB2; FGF11; FGF5; GNGT1; LAMB2; CCND1
    VEGF signaling pathway PIK3R2; PRKCBB; CDC42L; VEGFA; PLCG2; PTGS2A; HSPB1; KRAS; MAP2K2A; RAC3B
    Focal adhesion FLNA; TLN2A; MYL9B; TNXB; FYNB; CAV1; PDGFAB; MYL12.2; PARVA; COL27A1
    Pathways in cancer PIK3R2; MMP9; AXIN2; WNT1; CXCR4; RASSF5; DAPK2; AKT1; PDGFRB; HSP90AB1
    Proteoglycans in cancer MAPK3; ITGA5; WNT16; PTK2; THBS1; WNT3; CD63; PLCG2; ANK2; WNT10B
    MicroRNAs in cancer BMF; MAP2K1; HDAC4; TPM1; TRP63; HMGA2; PIM1; CCNE2; RPTOR; PRKCG
    Renal cell carcinoma RAP1B; PTPN11; RAC1; AHA-1; PAK7; TCEB1; MAPK3; RAP1A; FH1; ETS1
    Pancreatic cancer ERBB2; TGFB1; AKT2; MAPK10; TP53; PIK3R3; RAF1; PIK3R2; MAPK9; TGFBR1
    Bladder cancer FGFR3; CCND1; EGF; E2F3; MAP2K1; IL-8; NRAS; HBEGF; MAPK3; TP53
    Rheumatoid arthritis HLA-DQA1; ATP6V0A4; CCL2; ATP6V0A1; H2-AA; CXCL5; CCL5; CD80; HLA-DRA; CXCL6

    vegfa has several biochemical functions, for example, chemoattractant activity, cytokine activity, extracellular matrix binding. Some of the functions are cooperated with other proteins, some of the functions could acted by vegfa itself. We selected most functions vegfa had, and list some proteins which have the same functions with vegfa. You can find most of the proteins on our site.

    Function Related Protein
    chemoattractant activity CCL3; VEGFC; LGALS3; SAA1; HMGB1; VEGFA; FIGF; MIF; SAA4; CCL15
    cytokine activity IL18; KITLG; TNFSF8; CMTM5; FAM3D; GDF3; HMGB1B; IFNPHI1; MSTN; TNFSF12
    extracellular matrix binding CYR61; VEGFA; FBLN2; SPARC; VTN; ITGB3; SID4; ITGA2B; TGFBI; BGN
    fibronectin binding IGFBP5A; ITGB3; IGFBP5; LRRC15; FBLN1; CTSS; PLEKHA2; THBS1; ITGA3; IGFBP5B
    growth factor activity TGFA; TGFB3; EGF; PGF; LACRT; FGF21; FGF1A; BMP7B; GDF11; FGF20A
    heparin binding TGFBR3; LIPI; OGN; CXCL13; REG4; BMP7; ITGAM; THBS3; NRP2; UBE4A
    identical protein binding KIRRELA; AGXT2L2; PDGFB; STIM1; PRPF3; RUNX1T1; FKBP8; RCAN1; SERPINA1E; TNPO3
    neuropilin binding SEMA3H; SEMA3C; SEMA3BL; SEMA3G; SEMA3FA; SEMA7A; SEMA3AA; SEMA3B; SEMA4E; SEMA3AB
    platelet-derived growth factor receptor binding PTPRJ; PDGFRB; PDGFAB; LYN; PDGFAA; FIGF; TYMP; PTEN; VEGFA; PDGFB
    protein binding CNKSR1; YEATS4; APOA4; ACSF2; CHD7; SLC6A20; AMMECR1; MUS81; PGAP2; VEGFA
    protein heterodimerization activity PDX1; SOX9; SMAD3; TGFB1; TPD52L2; MAPK6; Itgam&Itgb2; ADORA1; WHRN; H2AFJ
    protein homodimerization activity MAPK4; TPD52; NR2C1; UGT1A3; ABCD2; HNF1B; TCF3; GPD1L; CAT; CCBL1
    receptor agonist activity GAS6; NODAL; WNT4; VEGFA; WNT1; WNT3A; WNT7A; WNT8A; CXCL13; GREM1
    vascular endothelial growth factor receptor 1 binding VEGFB; VEGFA
    vascular endothelial growth factor receptor 2 binding PDCL3; ITGB3; GREM1; ITGA5; VEGFA
    vascular endothelial growth factor receptor binding VEGFA; CD2AP; FIGF

    vegfa has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with vegfa here. Most of them are supplied by our site. Hope this information will be useful for your research of vegfa.

    KDR; FLT1; NRP1

    Tan, GW; Kasuya, H; et al. Combination therapy of oncolytic herpes simplex virus HF10 and bevacizumab against experimental model of human breast carcinoma xenograft. INTERNATIONAL JOURNAL OF CANCER 136:1718-1730(2015).
    Lee, JE; Kim, C; et al. Novel Glycosylated VEGF Decoy Receptor Fusion Protein, VEGF-Grab, Efficiently Suppresses Tumor Angiogenesis and Progression. MOLECULAR CANCER THERAPEUTICS 14:470-479(2015).

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