Recombinant Human Colony Stimulating Factor 1 (macrophage)
| Cat.No. : | CSF1-1875H |
| Product Overview : | Recombinant HumanCSF1 was expressed in HEK 293 cells. Its molecular weight is 35000 and 40000Dalton. |
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- Gene Information
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| Cat. No. : | CSF1-1875H |
| Description : | Macrophagecolony-stimulating factor, or CSF1, is a secreted cytokine which influenceshematopoietic stem cells to differentiate into macrophages or other relatedcell types. Eukaryotic cells also produce CSF1 in order to combatintercellular viral infection. (See colony-stimulating factor.) CSF1 binds tothe Colony stimulating factor 1 receptor. It may also be involved indevelopment of the placenta. |
| Expression : | Human Cell Expressed |
| Source : | HEK 293 cells |
| Species : | Human |
| Form : | Lyophilized from a0.2 µm sterile filtered solution in 5 mM Tris-HCl + 80 mM Arginine, pH8.0. |
| Molecular Weight : | 35 and 40 kDa,homodimer, glycosylated |
| Purity : | > 95% The proteinwas resolved by SDS polyacrylamide gel electrophoresis and the gel wasstained with Coomassie blue. |
| Biological Activity : | 0.5 to 4 ng/mL ED50 |
| Endotoxin Level : | Endotoxin Free <1EU/µg |
| Specific Activity : | The specificactivity was determined by the dose-dependent stimulation of theproliferation of mouse M-NFS-60 cells (Mouse Myeloid Leukemia indicator cellline). |
| OfficialSymbol : | CSF1 |
| Gene Name : | CSF1 colony stimulating factor 1(macrophage) [ Homo sapiens ] |
| Synonyms : | CSF1; colonystimulating factor 1 (macrophage); MCSF; MGC31930; colony stimulating factor1; OTTHUMP00000013363; OTTHUMP00000013364; Macrophage colony stimulatingfactor; M-CSF; CSF-1; Lanimostim |
| Gene ID : | 1435 |
| mRNA Refseq : | NM_000757 |
| Protein Refseq : | NP_000748 |
| MIM : | 120420 |
| UniProt ID : | P09603 |
| Chromosome Location : | 1p21-p13 |
| Pathway : | Cytokine-cytokinereceptor interaction; Cytokines and Inflammatory Response; Hematopoietic celllineage; Integrins in angiogenesis; Integrins in angiogenesis; Osteoclastdifferentiation; Rheumatoid arthritis; Rheumatoid arthritis; Signaling eventsmediated by PTP1B; Signaling events mediated by TCPTP |
| Function : | cytokine activity;growth factor activity; macrophage colony stimulating factor receptorbinding; protein binding; protein homodimerization activity |
Products Types
| ◆ Lysates | ||
| CSF1-001MCL | Recombinant Mouse CSF1 cell lysate | +Inquiry |
| CSF1-1934HCL | Recombinant Human CSF1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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