Recombinant Human Interleukin 10 IL10-626H

Recombinant Human Interleukin 10

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Recombinant Human Interleukin 10

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Cat. No. : IL10-626H
Product Overview : IL10 isexpressed in human 293 cells as a non-covalent homodimeric glycoprotein with anapparent molecular mass of 17 kDa.
Description : IL10 isproduced in a serum-free, chemically defined media. Glycosylation contributesto stability in cell growth media and other applications. The cytokine isgreater than 95% pure.
Source : HEK 293 cells
Species : Human
Molecular Mass : 17 kDa
Purity : > 95%The protein was resolved by SDS polyacrylamide gel electrophoresis and thegel was stained with Coomassie blue.
Endotoxin Level : Endotoxin Free <1EU/μg
Biological Activity : 0.3 to 1.5 ng/mL ED50
Specific Activity : The specific activity wasdetermined by the dose-dependent stimulation of the proliferationof MC/9 cells (mouse master cell line) in presence of 200pg/mL IL-4.
OfficialSymbol : IL10
Gene Name : IL10interleukin 10 [ Homo sapiens ]
Synonyms : IL10; interleukin10; CSIF; TGIF; IL-10; IL10A; MGC126450; MGC126451; cytokine synthesisinhibitory factor; T-cell growth inhibitory factor; OTTHUMP00000034567; Interleukin-10
Gene ID : 3586
mRNA Refseq : NM_000572
Protein Refseq : NP_000563
MIM : 124092
UniProt ID : P22301
Chromosome Location : 1q31-q32
Pathway : Africantrypanosomiasis; Allograft rejection; Amoebiasis; Asthma; Autoimmune thyroiddisease; Chagas disease (American trypanosomiasis); Cytokine-cytokinereceptor interaction; Cytokines and Inflammatory Response; IL4-mediatedsignaling events; Intestinal immune network for IgA production; Jak-STATsignaling pathway; Leishmaniasis; Malaria; Pertussis; Regulation of nuclearSMAD2/3 signaling
Function : growthfactor activity; cytokine activity; interleukin-10receptor binding

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