Recombinant Human Interleukin 10


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Recombinant Human Interleukin 10

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Cat. No. : IL10-626H
Product Overview : IL10 isexpressed in human 293 cells as a non-covalent homodimeric glycoprotein with anapparent molecular mass of 17 kDa.
Description : IL10 isproduced in a serum-free, chemically defined media. Glycosylation contributesto stability in cell growth media and other applications. The cytokine isgreater than 95% pure.
Source : HEK 293 cells
Species : Human
Molecular Mass : 17 kDa
Purity : > 95%The protein was resolved by SDS polyacrylamide gel electrophoresis and thegel was stained with Coomassie blue.
Endotoxin Level : Endotoxin Free <1EU/μg
Biological Activity : 0.3 to 1.5 ng/mL ED50
Specific Activity : The specific activity wasdetermined by the dose-dependent stimulation of the proliferationof MC/9 cells (mouse master cell line) in presence of 200pg/mL IL-4.
OfficialSymbol : IL10
Gene Name : IL10interleukin 10 [ Homo sapiens ]
Synonyms : IL10; interleukin10; CSIF; TGIF; IL-10; IL10A; MGC126450; MGC126451; cytokine synthesisinhibitory factor; T-cell growth inhibitory factor; OTTHUMP00000034567; Interleukin-10
Gene ID : 3586
mRNA Refseq : NM_000572
Protein Refseq : NP_000563
MIM : 124092
UniProt ID : P22301
Chromosome Location : 1q31-q32
Pathway : Africantrypanosomiasis; Allograft rejection; Amoebiasis; Asthma; Autoimmune thyroiddisease; Chagas disease (American trypanosomiasis); Cytokine-cytokinereceptor interaction; Cytokines and Inflammatory Response; IL4-mediatedsignaling events; Intestinal immune network for IgA production; Jak-STATsignaling pathway; Leishmaniasis; Malaria; Pertussis; Regulation of nuclearSMAD2/3 signaling
Function : growthfactor activity; cytokine activity; interleukin-10receptor binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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