Recombinant Rhesus macaque IL10 Protein, His-tagged
Cat.No. : | IL10-22R |
Product Overview : | Recombinant Rhesus macaque IL10(19-178aa) fused with His tag at N-terminal was expressed in Yeast. |
- Specification
- Gene Information
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Description : | IL10 played an important role in many funtions. |
Source : | Yeast |
Species : | Rhesus macaque |
Tag : | His |
Form : | Tris-based buffer, 50% glycerol |
Molecular Mass : | 20.7kDa |
Protein length : | 19-178aa |
AA Sequence : | SPGQGTQSENSCTRFPGNLPHMLRD LRDAFSRVKTFFQMKDQLDNILLKE SLLEDFKGYLGCQALSEMIQFYLEE VMPQAENHDPDIKEHVNSLGENLKT LRLRLRRCHRFLPCENKSKAVEQVK NAFSKLQEKGVYKAMSEFDIFINYI EAYMTMKIQN |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Stability : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Gene Name : | IL10 interleukin 10 [ Macaca mulatta ] |
Official Symbol : | IL10 |
Synonyms : | CSIF; IL-10; cytokine synthesis inhibitory factor |
Gene ID : | 694931 |
mRNA Refseq : | NM_001044727 |
Protein Refseq : | NP_001038192 |
UniProt ID : | P51496 |
Products Types
◆ Recombinant Protein | ||
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IL10-134H | Recombinant Active Human IL10 Protein, His-tagged(C-ter) | +Inquiry |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionCutting-edge imaging techniques, alongside in vivo disease models, allow for precise assessment of therapeutic effects and tissue responses to IL-10-based treatments.
Advanced technologies, including single-cell RNA sequencing and flow cytometry, enable a granular analysis of IL-10's impact on diverse immune cell subpopulations.
Genotyping studies and genetic association analyses help correlate variations in IL-10 and its receptor with disease susceptibility across diverse populations.
Advanced immunomonitoring tools, including multiplex cytokine assays and immune cell phenotyping, provide comprehensive safety evaluations of IL-10 interventions in clinical trials.
In vitro models involve exposing immune cells to IL-10 and assessing changes in cytokine secretion and cell activation markers to uncover its anti-inflammatory mechanisms.
State-of-the-art techniques such as phosphoproteomics, mass spectrometry, and protein-protein interaction assays provide insights into the intricate signaling cascades activated by IL-10.
Dose-response studies in animal models coupled with outcome measures like cytokine profiles and immune cell phenotypes help determine the optimal IL-10 dosage and administration routes.
Experimental designs encompass co-stimulation experiments, coupled with functional assays and high-dimensional analysis, to elucidate synergistic effects involving IL-10 and other cytokines.
Techniques like RT-PCR, immunohistochemistry, and spatial transcriptomics are employed to characterize IL-10 receptor expression patterns in specific tissues and disease contexts.
CRISPR/Cas9 gene editing is used to create knockout or overexpression models, combined with functional assays, to decipher IL-10's regulatory roles in autoimmune disease pathways.
Customer Reviews (3)
Write a reviewEffective in anti-inflammatory assays.
High purity levels.
Stable under long-term storage.
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