Recombinant Human Platelet-Derived Growth Factor Receptor, Alpha Polypeptide, GST-tagged
Cat.No. : | PDGFRA-1287H |
Product Overview : | Recombinant humanPDGFRA catalytic domain (amino acids 550-1089), GST-tagged was expressed ininsect cells. Its molecular weight is 89800 Dalton. |
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- Gene Information
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Cat. No. : | PDGFRA-1287H |
Description : | PDGFRA is a cellsurface receptor tyrosine kinase which binds members of the platelet-derivedgrowth factor family. No special measures were taken to activate this kinase.PDGFRA encodes a cell surface tyrosine kinase receptor for members of theplatelet-derived growth factor family. These growth factors are mitogens forcells of mesenchymal origin. The identity of the growth factor bound to areceptor monomer determines whether the functional receptor is a homodimer ora heterodimer, composed of both platelet-derived growth factor receptor alphaand beta polypeptides. |
Source : | Insect cells |
Species : | Human |
Form : | Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT + 50%glycerol. |
Molecular Weight : | 89.8 kDa |
Storage : | Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | PDGFRA |
Gene Name : | PDGFRA platelet-derived growth factor receptor,alpha polypeptide [ Homo sapiens ] |
Synonyms : | PDGFRA;platelet-derived growth factor receptor, alpha polypeptide; CD140A; CD140a;PDGFR2; MGC74795; RHEPDGFRA; Alpha-type platelet-derived growth factorreceptor; EC 2.7.10.1; PDGF-R-alpha; CD140 antigen-like family member A;CD140a antigen |
Gene ID : | 5156 |
mRNA Refseq : | NM_006206 |
Protein Refseq : | NP_006197 |
MIM : | 173490 |
UniProt ID : | P16234 |
Chromosome Location : | 4q12 |
Pathway : | ATF-2 transcriptionfactor network; Calcium signaling pathway; Cytokine-cytokine receptorinteraction; Downstream signal transduction; Endocytosis; Focal adhesion; Gapjunction; Glioma; HTLV-I infection; MAPK signaling pathway; Melanoma;Pathways in cancer; PDGFR-alpha signaling pathway; Regulation of actin cytoskeleton;Signaling by PDGF |
Function : | ATP binding; growthfactor binding; nucleotide binding; phosphatidylinositol 3-kinase binding;platelet-derived growth factor alpha-receptor activity; platelet-derivedgrowth factor binding; platelet-derived growth factor receptor binding;protein homodimerization activity; protein tyrosine kinase activity; receptoractivity; transmembrane receptor protein tyrosine kinase activity; vascularendothelial growth factor-activated receptor activity |
Products Types
◆ Recombinant Protein | ||
PDGFRA-188H | Recombinant Human PDGFRA Protein, His-tagged | +Inquiry |
PDGFRA-37H | Recombinant Active Human PDGFR alpha (G680R) Mutant Protein, GST-tagged | +Inquiry |
Pdgfra-4758M | Recombinant Mouse Pdgfra Protein, Myc/DDK-tagged | +Inquiry |
PDGFRA-1282R | Recombinant Rat PDGFRA protein(Met1-Glu523), hFc-tagged | +Inquiry |
Pdgfra-99M | Recombinant Mouse Pdgfra Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PDGFRA-2657HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
PDGFRA-001HCL | Recombinant Human PDGFRA cell lysate | +Inquiry |
PDGFRA-824RCL | Recombinant Rat PDGFRA cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1615 | PDGFRa Functional Assay Kit | +Inquiry |
Kit-1616 | U2OS PDGFRa Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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