PDGFRA

  • Official Full Name

    platelet-derived growth factor receptor, alpha polypeptide

  • Overview

    This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Synonyms

    PDGFRA; platelet-derived growth factor receptor, alpha polypeptide; platelet-derived growth factor receptor alpha; CD140a; PDGFR2; PDGFR-alpha; PDGF-R-alpha; CD140a antigen; PDGFRA/BCR fusion; CD140 antigen-like family member A; platelet-derived growth factor receptor 2; alpha-type platelet-derived growth factor receptor; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; CD140A; PDGFR-2; RHEPDGFRA; MGC74795;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chromatography Reagents
  • Assay Kits
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293T
  • Human
  • Human Cell
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • C
  • Fc
  • hFc
  • His
  • DDDDK
  • DDK|His
  • Fc|His
  • His(C
  • ter)
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PDGFRA-29161TH Active Recombinant Human PDGFRA protein, GST-tagged Insect Cell GST
Human PDGFRA-662H Active Recombinant Human PDGFRA, Fc-tagged, Biotinylated Human Cell Fc
Human PDGFRA-051H Active Recombinant Human PDGFRA protein, His/Avi-tagged, Biotinylated HEK293 cells His/Avi Gln24-Glu524
Human PDGFRA-384H Recombinant Human PDGFRA, GST-tagged, Active Sf9 Insect Cell GST
Human PDGFRA-1612H Recombinant Human PDGFRA, GST-tagged E.coli GST N-term-209aa
Human PDGFRA-1676H Recombinant Human PDGFRA Mammalian cells N/A
Human PDGFRA-30830TH Recombinant Human PDGFRA N/A
Human PDGFRA-7290H Recombinant Human PDGFRA, His & GST tagged Insect Cell His/GST
Human PDGFRA-1287H Recombinant Human Platelet-Derived Growth Factor Receptor, Alpha Polypeptide, GST-tagged Insect Cell GST
Human PDGFRA-824H Recombinant Human PDGFRA, Fc tagged Human Cell Fc
Human PDGFRA-147H Recombinant Human PDGFRA Protein, DDK/HIS-tagged HEK293 DDK/His Gln24-Ala528
Human PDGFRA-3181H Recombinant Human PDGFRA protein, His-tagged HEK293 His Gln24-Ala528
Human PDGFRA-825H Recombinant Human PDGFRA, None tagged Human Cell N/A
Human PDGFRA-3560H Recombinant Human PDGFRA, His-tagged E.coli His
Human PDGFRA-1576H Recombinant Human Platelet-Derived Growth Factor Receptor, Alpha Polypeptide Sf9 Insect Cell N/A
Human PDGFRA-1147H Recombinant Human Platelet-Derived Growth Factor Receptor, Alpha Polypeptide, His-tagged Human His
Human PDGFRA-001HCL Recombinant Human PDGFRA cell lysate Insect Cell N/A
Human PDGFRA-2657HCL Recombinant Human PDGFRA cell lysate Human Cell N/A
Human PDGFRA-824HAF488 Recombinant Human PDGFRA Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 739
Human PDGFRA-7290HAF488 Recombinant Human PDGFRA Protein, His/GST-tagged, Alexa Fluor 488 conjugated Insect Cells His/GST 776
Human PDGFRA-0252H Active Recombinant Human PDGFRA protein, His-tagged HEK293 His Met1-Glu524
Human PDGFRA-2050H Recombinant Human PDGFRA Protein, Fc/His-tagged HEK293 Fc/His Gln24-Glu524
Human PDGFRA-7290HAF555 Recombinant Human PDGFRA Protein, His/GST-tagged, Alexa Fluor 555 conjugated Insect Cells His/GST 776
Human PDGFRA-825HAF488 Recombinant Human PDGFRA Protein, DDDDK-tagged, Alexa Fluor 488 conjugated HEK293 DDDDK 507
Human PDGFRA-188H Recombinant Human PDGFRA Protein, His-tagged E.coli His Ala170~Glu387
Human PDGFRA-234HB Recombinant Human PDGFRA protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Met1-Glu524
Human PDGFRA-3181HAF647 Recombinant Human PDGFRA Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His Gln24-Ala528
Human PDGFRA-3181HAF555 Recombinant Human PDGFRA Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His Gln24-Ala528
Human PDGFRA-716H Recombinant Human PDGFRA Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PDGFRA-234H Recombinant Human PDGFRA protein, His-Avi-tagged HEK293 His-Avi Met1-Glu524
Human PDGFRA-824HF Recombinant Human PDGFRA Protein, Fc-tagged, FITC conjugated HEK293 Fc 739
Human PDGFRA-7290HAF647 Recombinant Human PDGFRA Protein, His/GST-tagged, Alexa Fluor 647 conjugated Insect Cells His/GST 776
Human PDGFRA-37H Recombinant Active Human PDGFR alpha (G680R) Mutant Protein, GST-tagged Insect Cell GST
Human PDGFRA-3181HAF488 Recombinant Human PDGFRA Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His Gln24-Ala528
Human PDGFRA-1633H Recombinant Human PDGFRA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PDGFRA-7290HF Recombinant Human PDGFRA Protein, His/GST-tagged, FITC conjugated Insect Cells His/GST 776
Human PDGFRA-38H Recombinant Active Human PDGFR alpha (E675G Y676C) Mutant Protein, GST-tagged Insect Cell GST
Human PDGFRA-824HAF555 Recombinant Human PDGFRA Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 739
Human PDGFRA-2647H Active Recombinant Human PDGFRA protein, hFc&His-tagged HEK293 hFc&His Gln24-Glu524
Human PDGFRA-4842H Recombinant Human PDGFRA Protein (Met1-IIe834), C-His tagged E.coli C-His Met1-IIe834
Human PDGFRA-2884H Recombinant Human PDGFRA protein, His-tagged E.coli His 24-123 aa
Human PDGFRA-825HAF555 Recombinant Human PDGFRA Protein, DDDDK-tagged, Alexa Fluor 555 conjugated HEK293 DDDDK 507
Human PDGFRA-1633H-B Recombinant Human PDGFRA Protein Pre-coupled Magnetic Beads HEK293
Human PDGFRA-824HAF647 Recombinant Human PDGFRA Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 739
Human PDGFRA-3181HF Recombinant Human PDGFRA Protein, His-tagged, FITC conjugated HEK293 His Gln24-Ala528
Human PDGFRA-825HAF647 Recombinant Human PDGFRA Protein, DDDDK-tagged, Alexa Fluor 647 conjugated HEK293 DDDDK 507
Human PDGFRA-270H Recombinant Human PDGFRA Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter) Gln24-Glu524
Human PDGFRA-825HF Recombinant Human PDGFRA Protein, DDDDK-tagged, FITC conjugated HEK293 DDDDK 507
Human PDGFRA-111H Recombinant Human PDGFRA Protein, C-His-tagged E.coli C-His
Human PDGFRA-1498HFL Recombinant Full Length Human PDGFRA Protein, C-Flag-tagged Mammalian cells Flag
Human PDGFRA-4841H Recombinant Human PDGFRA Protein (Met1-Glu524), C-His tagged Mammalian cells C-His Met1-Glu524
Mouse Pdgfra-1774M Active Recombinant Mouse Pdgfra Protein, Fc-tagged Mammalian cells Fc
Mouse PDGFRA-12570M Recombinant Mouse PDGFRA Protein Mammalian Cell His
Mouse Pdgfra-385M Recombinant Mouse Pdgfra, GST-tagged, Active Sf9 Insect Cell GST
Mouse Pdgfra-4758M Recombinant Mouse Pdgfra Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PDGFRA-6767M Recombinant Mouse PDGFRA Protein (Leu25-Glu524), C-His tagged Mammalian cells C-His Leu25-Glu524
Mouse Pdgfra-99M-B Recombinant Mouse Pdgfra Protein Pre-coupled Magnetic Beads HEK293
Mouse Pdgfra-5726M Recombinant Mouse Pdgfra Protein (Leu25-Glu524), C-Fc tagged Mammalian cells C-Fc Leu25-Glu524
Mouse PDGFRA-6942M PDGFRA protein-coupled magnetic MicroBeads
Mouse Pdgfra-99M Recombinant Mouse Pdgfra Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PDGFRA-0282M Recombinant Mouse PDGFRA protein, hFc-tagged HEK293 hFc Met1-Ala528
Rat Pdgfra-51R Recombinant Rat Pdgfra, Fc tagged Human Cell His
Rat Pdgfra-52R Recombinant Rat Pdgfra, His tagged Human Cell His
Rat PDGFRA-824RCL Recombinant Rat PDGFRA cell lysate Human Cell N/A
Rat Pdgfra-51RAF488 Recombinant Rat Pdgfra Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 741
Rat Pdgfra-52RAF488 Recombinant Rat Pdgfra Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 511
Rat Pdgfra-51RF Recombinant Rat Pdgfra Protein, Fc-tagged, FITC conjugated HEK293 Fc 741
Rat Pdgfra-51RAF555 Recombinant Rat Pdgfra Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 741
Rat Pdgfra-52RAF555 Recombinant Rat Pdgfra Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 511
Rat PDGFRA-1282R Recombinant Rat PDGFRA protein(Met1-Glu523), hFc-tagged HEK293 C-hFc Met1-Glu523
Rat Pdgfra-51RAF647 Recombinant Rat Pdgfra Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 741
Rat Pdgfra-52RAF647 Recombinant Rat Pdgfra Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 511
Rat Pdgfra-52RF Recombinant Rat Pdgfra Protein, His-tagged, FITC conjugated HEK293 His 511
Zebrafish PDGFRA-9027Z Recombinant Zebrafish PDGFRA Mammalian Cell His
Chicken PDGFRA-6314C Recombinant Chicken PDGFRA Mammalian Cell His
Kit-1615 PDGFRa Functional Assay Kit N/A
Kit-1616 U2OS PDGFRa Bioassay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PDGFRA Related Articles
  • PDGFRA Related Gene Family
  • PDGFRA Related Research Area

PDGFRA involved in several pathways and played different roles in them. We selected most pathways PDGFRA participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDGFRA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayFGF1;FAS;CACNG7;RAC3A;MAP2K5;GRB2B;TGFBR2;MAP3K5;CACNA1C
Ras signaling pathwayMAPK1;FGF2;CALML3;GNG3;IKBKG;PAK3;MAP2K1;PIK3CD;Fasl
Rap signaling pathwayGNAI1;TEK;CALM3;PIK3CD;VEGFB;PDGFRB;PDGFA;PGF;ITGA2B
Calcium signaling pathwayDRD1;PRKACAA;MYLK3;AVPR1A;STIM2;ADRB1;ERBB4;PRKCA;ATP2A1L
Cytokine-cytokine receptor interactionPRL;MET;CRFB4;IL5;GM10591;CCL13;KITB;TGFB2;CSF1R
Phospholipase D signaling pathwayPLCB2;IL-8;GRM3;AKT1;RAF1;Kitl;ARF6;MAPK1;RRAS
EndocytosisWIPF1;ARFGEF2;ERBB4A;ARFGAP2;GIT1;GRK7B;RAB31;HSPA1B;HSP70L
PIK-Akt signaling pathwayITGA4;BAD;FGF22;PKN3;NFKB1;PDGFA;F2R;PHLPP2;GNGT1
Focal adhesionDIAP1;PIK3CA;PPP1R12B;VTN;PRKCBA;RAF1;PPP1CBL;CAV2;ROCK1
Gap junctionHRASB;TJP1;Adcy4;MAP2K2B;ADRB3A;RAF1B;PDGFRA;GUCY1A3;DRD2L
Regulation of actin cytoskeletonCD14;DIAPH3;Itga10&Itgb1;ABI2A;LIMK1;FGF1A;MYLK;GSNB;FGD1
HTLV-I infectionFZD6;Il2;CDC20;HLA-DMA;STAT5A;POLD4;HLA-DOB;IL6;CRTC2
Pathways in cancerAPPL1;FGF9;FGFR3;PIK3R2;CCNA1;FGF21;VEGFA;FLT3;BIRC7
MicroRNAs in cancerSOS1;MMP9;Abcb1b;IGF2BP1;PIM1;DICER1;DDIT4;PTEN;ROCK1
GliomaRAF1;MAP2K1;PIK3R2;PRKCB;CALM4;PIK3CA;Pdgfa&Pdgfb;SHC1;GRB2
Prostate cancerPIK3R2;CREB3L3;NKX3;TCF7;AKT1;FOXA1;FOXO1;MAPK3;FGFR1
MelanomaBAD;NRAS;FGF2;MAPK1;IGF1;PIK3R1;CDH1;IGF1R;PIK3R2
Central carbon metabolism in cancerPIK3R2;PFKP;HKDC1;SIRT6;PDHA2;HRAS;SLC2A1;PKM2;FLT3
Choline metabolism in cancerSLC22A2;DGKZ;DGKQ;PDPK1;SLC44A2;PLCG1;LYPLA1;PIK3R5;PIP5K1B

PDGFRA has several biochemical functions, for example, ATP binding, platelet-derived growth factor alpha-receptor activity, platelet-derived growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDGFRA itself. We selected most functions PDGFRA had, and list some proteins which have the same functions with PDGFRA. You can find most of the proteins on our site.

Function Related Protein
ATP bindingWRNIP1;DDX17;AGAP2;TEC;HSC70;NADKD1;MYH1B;MAPK1;ABL2
platelet-derived growth factor alpha-receptor activity
platelet-derived growth factor bindingPDGFRA;COL1A1;PDGFB;PDGFA;Pdgfa&Pdgfb;COL5A1;COL2A1;COL4A1;PDGFRB
platelet-derived growth factor receptor bindingIL1R1;PDGFB;PDGFAB;PDGFA;PDGFC;TYMP;Pdgfa&Pdgfb;PDGFAA;ITGA5
protein bindingHP1BP3;PPIAL4A;TXLNG;IARS;ACTR6;EXOC3L;KIF27;THAP7;CDK20
protein homodimerization activityNR2C1;CHRNA7;PTPRE;STK25;GPD1C;CADM3;LGALS1;ECT2;CHMP3
protein kinase activityPAK1;NRBP2;SLKA;AVP;ACVR1BA;MYO3A;STK26;GSK3AB;SCYL2
transmembrane receptor protein tyrosine kinase activityALK;NTRK1;NPTN;EGFRA;EPHA2A;EPHB4B;IGF1RA;EPHB2B;MERTK
vascular endothelial growth factor bindingPDGFRB;NRP1;KDR;PDGFRA
vascular endothelial growth factor-activated receptor activityNRP2B;NRP1B;NRP2A;NRP1;FLT1;PDGFRA;FLT4;NRP2;FLT3

PDGFRA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDGFRA here. Most of them are supplied by our site. Hope this information will be useful for your research of PDGFRA.

PDGFB; CRK; PDGFA

Yi, JH; Park, BB; et al. Retrospective analysis of extra-gastrointestinal stromal tumors. WORLD JOURNAL OF GASTROENTEROLOGY 21:1845-1850(2015).
Albuquerque, A; Rios, E; et al. Evaluation of clinico-pathological features and Helicobacter pylori infection in gastric inflammatory fibroid polyps. VIRCHOWS ARCHIV 465:643-647(2014).
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