||Recombinant human IL2RA is a 24.8 kDa protein containing 219 aminoacid residues consisting of only the extracellular domain of IL2RA. Due to glycosylation, IL2RA has an approximate molecular weight of 31 kDabased on SDS-PAGE gel and Mass Spectrometry.
||TheIL-2 receptor system consists of three non-covalently linked subunits termed IL2RA, IL-2R beta, and IL-2R gamma. The IL2RA is a type I transmembrane protein consistingof a 219 amino acid extracellular domain, a 19 amino acid transmembranedomain and a 13 amino acid intracellular domain, which is not involved in thetransduction of IL-2 signals.
||> 95.0% asdetermined by RP-HPLC and SDS-PAGE analyses
||<0.1 ng per µg ofIL2RA
||Determined by itsability to increase the proliferation effect of IL-2 in mouse CTLL-2 cells.In the presence of 1 ng/ml of recombinant IL-2, the expected ED50for this effect is between 0.5-1.5 µg/ml.