IL2RA Protein

IL2RA

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IL2RA

Official Full Name interleukin 2 receptor, alpha
Background Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
Synonyms Interleukin 2 receptor alpha chain; CD 25; CD25; CD25 antigen; IDDM10; IL 2 RA; IL 2 receptor alpha subunit; IL 2R; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2 RA; IL2R; IL2RA_HUMAN; IL2RAC; Interleukin 2 Receptor Alpha; Interleukin 2 receptor; Interleukin-2 receptor subunit alpha; Ly43; p55; T Cell Growth Factor Receptor; TAC; TAC Antigen; TCGFR; interleukin 2 receptor, alpha
    • Species :
    • Bos taurus (Bovine)
    • Canine
    • Canis lupus familiaris (Dog) (Canis familiaris)
    • Cattle
    • Chicken
    • Cynomolgus Monkey
    • Felis catus (Cat) (Felis silvestris catus)
    • Homo sapiens (Human)
    • Human
    • Monkey
    • Mouse
    • Mus musculus (Mouse)
    • Ovis aries (Sheep)
    • Pig
    • Rat
    • Rattus norvegicus (Rat)
    • Rhesus
    • Rhesus Macaque
    • Sus scrofa (Pig)
    • Source :
    • CHO
    • E.coli
    • E.coli expression system
    • HEK293
    • HEK293 cells
    • Hi-5 Insect Cell
    • Human Cell
    • Human Cells
    • In Vitro Cell Free System
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • C-Avi&His
    • DYKDDDDK
    • Fc
    • Fc/Avi
    • GST
    • hFc
    • hIgG-His-Tag
    • His
    • His & Avi
    • His(C-ter)
    • His\Avi
    • S
    • T7
    • His-Avi
    • human
    • IgG1
    • LEVLFQ
    • N/A
    • N-His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL2RA-4951H Active Recombinant Human IL2RA Insect Cell N/A Inquiry
    Human IL2RA-948H Active Recombinant Human IL2RA Protein Hi-5 Insect Cell N/A Inquiry
    Mouse Il2ra-5654M Active Recombinant Mouse Interleukin 2 Receptor, Alpha Chain, His-tagged Mammalian cells His Inquiry
    Rat Il2ra-474R Active Recombinant Rat Interleukin 2 Receptor, Alpha CHO N/A Inquiry
    Canine IL2RA-460C Active Recombinant Canine IL2RA, His-tagged Mammalian cells His Inquiry
    Human IL2RA-051H Active Recombinant Human IL2RA protein, Fc/Avi-tagged, Biotinylated HEK293 cells Fc/Avi Inquiry
    Canine IL2RA-2182C Active Recombinant Canine IL2RA protein, His-tagged HEK293 His Inquiry
    Human IL2RA-1237H Recombinant Human Interleukin 2 Receptor, Alpha Insect Cell N/A Inquiry
    Human IL2RA-1325H Recombinant Human Interleukin 2 Receptor, Alpha, GST-tagged E.coli GST Inquiry
    Human IL2RA-170H Recombinant Human IL2RA protein, Fc-tagged HEK293 human/IgG1/Fc Inquiry
    Human IL2RA-636H Recombinant Human IL2RA, Fc tagged Human Cell Fc Inquiry
    Human IL2RA-637H Recombinant Human IL2RA, His tagged Human Cell His Inquiry
    Human IL2RA-99H Recombinant Human IL2RA protein, His-tagged E.coli His Inquiry
    Mouse Il2ra-1865M Recombinant Mouse Il2ra protein, His & S-tagged E.coli His/S Inquiry
    Mouse Il2ra-4021M Recombinant Mouse Il2ra protein, His-tagged HEK293 His Inquiry
    Rat Il2ra-1867R Recombinant Rat Il2ra protein, His-tagged E.coli His Inquiry
    Rat Il2ra-1868R Recombinant Rat Il2ra protein, His & S-tagged E.coli His/S Inquiry
    Rat IL2RA-3043R Recombinant Rat IL2RA Protein Mammalian Cell His Inquiry
    Cynomolgus Monkey IL2RA-133C Recombinant Cynomolgus IL2RA, Fc tagged Human Cell His Inquiry
    Cynomolgus Monkey IL2RA-134C Recombinant Cynomolgus IL2RA, His tagged Human Cell His Inquiry
    Cynomolgus Monkey IL2RA-135C Recombinant Cynomolgus IL2RA, LEVLFQ tagged Human Cell Fc Inquiry
    Cynomolgus Monkey IL2RA-618C Recombinant Cynomolgus IL2RA Protein, His-tagged Mammalian Cell His Inquiry
    Rhesus Macaque IL2RA-2247R Recombinant Rhesus monkey IL2RA Protein, His-tagged Mammalian Cell His Inquiry
    Chicken IL2RA-6165C Recombinant Chicken IL2RA Mammalian Cell His Inquiry
    Cattle IL2RA-1864C Recombinant Cattle IL2RA protein, His & T7-tagged E.coli His/T7 Inquiry
    Pig IL2RA-1866P Recombinant Pig IL2RA protein, His & T7-tagged E.coli His/T7 Inquiry
    Human IL2RA-2907HCL Recombinant Human IL2RA cell lysate Human Cell N/A Inquiry
    Mouse IL2RA-2024MCL Recombinant Mouse IL2RA cell lysate Human Cell N/A Inquiry
    Cynomolgus Monkey IL2RA-1015CCL Recombinant Cynomolgus IL2RA cell lysate Human Cell N/A Inquiry
    Human IL2RA-01H Recombinant Human IL2RA protein, hIgG-His-tagged Insect Cell hIgG-His-Tag Inquiry
    Monkey IL2RA-133CAF488 Recombinant Monkey IL2RA Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
    Monkey IL2RA-133CAF555 Recombinant Monkey IL2RA Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
    Monkey IL2RA-133CAF647 Recombinant Monkey IL2RA Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
    Monkey IL2RA-133CF Recombinant Monkey IL2RA Protein, Fc-tagged, FITC conjugated HEK293 Fc
    Monkey IL2RA-134CAF488 Recombinant Cynomolgus IL2RA Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Monkey IL2RA-134CAF555 Recombinant Cynomolgus IL2RA Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Monkey IL2RA-134CAF647 Recombinant Cynomolgus IL2RA Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Monkey IL2RA-134CF Recombinant Cynomolgus IL2RA Protein, His-tagged, FITC conjugated HEK293 His
    Monkey IL2RA-135CAF488 Recombinant Cynomolgus IL2RA Protein, LEVLFQ-tagged, Alexa Fluor 488 conjugated HEK293 LEVLFQ
    Monkey IL2RA-135CAF555 Recombinant Cynomolgus IL2RA Protein, LEVLFQ-tagged, Alexa Fluor 555 conjugated HEK293 LEVLFQ
    Monkey IL2RA-135CAF647 Recombinant Cynomolgus IL2RA Protein, LEVLFQ-tagged, Alexa Fluor 647 conjugated HEK293 LEVLFQ
    Monkey IL2RA-135CF Recombinant Cynomolgus IL2RA Protein, LEVLFQ-tagged, FITC conjugated HEK293 LEVLFQ
    Human IL2RA-151H Recombinant Human IL2RA Protein, DYKDDDDK-tagged Human Cells DYKDDDDK Inquiry
    Mouse Il2ra-1676M Recombinant Mouse Il2ra Protein, His-tagged E.coli N-His Inquiry
    Mouse Il2ra-1677M Recombinant Mouse Il2ra Protein, His-tagged E.coli N-His Inquiry
    Human IL2RA-170HAF488 Recombinant Human IL2RA Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 hFc
    Human IL2RA-170HAF555 Recombinant Human IL2RA Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 hFc
    Human IL2RA-170HAF647 Recombinant Human IL2RA Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 hFc
    Human IL2RA-170HF Recombinant Human IL2RA Protein, hFc-tagged, FITC conjugated HEK293 hFc
    Human IL2RA-179I Recombinant Human IL2RA Protein (205 aa), His-tagged HEK293 His Inquiry
    Human IL2RA-186H Recombinant Human IL2RA Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter) Inquiry
    Human IL2RA-216H Recombinant Human IL2RA Protein, His\Avi-tagged HEK293 His\Avi Inquiry
    Rhesus IL2RA-247R Recombinant Rhesus IL2RA protein, His & Avi-tagged, Biotinylated HEK293 His & Avi Inquiry
    Mouse Il2ra-4021MAF488 Recombinant Mouse Il2ra Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Mouse Il2ra-4021MAF555 Recombinant Mouse Il2ra Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Mouse Il2ra-4021MAF647 Recombinant Mouse Il2ra Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Mouse Il2ra-4021MF Recombinant Mouse Il2ra Protein, His-tagged, FITC conjugated HEK293 His
    Human IL2RA-43H Recombinant Human IL2RA Protein, C-Avi&His tagged, Biotinylated HEK293 C-Avi&His Inquiry
    Human IL2RA-5756HF Recombinant Full Length Human IL2RA Protein In Vitro Cell Free System Inquiry
    Human IL2RA-636HAF488 Recombinant Human IL2RA Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
    Human IL2RA-636HAF555 Recombinant Human IL2RA Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
    Human IL2RA-636HAF647 Recombinant Human IL2RA Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
    Human IL2RA-636HF Recombinant Human IL2RA Protein, Fc-tagged, FITC conjugated HEK293 Fc
    Human IL2RA-637HAF488 Recombinant Human IL2RA Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
    Human IL2RA-637HAF555 Recombinant Human IL2RA Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
    Human IL2RA-637HAF647 Recombinant Human IL2RA Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
    Human IL2RA-637HF Recombinant Human IL2RA Protein, His-tagged, FITC conjugated HEK293 His
    Ovis aries (Sheep) RFL15135OF Recombinant Full Length Sheep Interleukin-2 Receptor Subunit Alpha(Il2Ra) Protein, His-Tagged E.coli expression system His Inquiry
    Rattus norvegicus (Rat) RFL15962RF Recombinant Full Length Rat Interleukin-2 Receptor Subunit Alpha(Il2Ra) Protein, His-Tagged E.coli expression system His Inquiry
    Homo sapiens (Human) RFL19373HF Recombinant Full Length Human Interleukin-2 Receptor Subunit Alpha(Il2Ra) Protein, His-Tagged E.coli expression system His Inquiry
    Mus musculus (Mouse) RFL25627MF Recombinant Full Length Mouse Interleukin-2 Receptor Subunit Alpha(Il2Ra) Protein, His-Tagged E.coli expression system His Inquiry
    Felis catus (Cat) (Felis silvestris catus) RFL26789FF Recombinant Full Length Cat Interleukin-2 Receptor Subunit Alpha(Il2Ra) Protein, His-Tagged E.coli expression system His Inquiry
    Canis lupus familiaris (Dog) (Canis familiaris) RFL33866CF Recombinant Full Length Dog Interleukin-2 Receptor Subunit Alpha(Il2Ra) Protein, His-Tagged E.coli expression system His Inquiry
    Bos taurus (Bovine) RFL7065BF Recombinant Full Length Bovine Interleukin-2 Receptor Subunit Alpha(Il2Ra) Protein, His-Tagged E.coli expression system His Inquiry
    Sus scrofa (Pig) RFL934SF Recombinant Full Length Pig Interleukin-2 Receptor Subunit Alpha(Il2Ra) Protein, His-Tagged E.coli expression system His Inquiry
    Human IL2RA-025H Recombinant Human IL2RA protein, His-Avi-tagged HEK293 His-Avi Inquiry
    Human IL2RA-170HA Recombinant Human IL2RA protein, Fc-tagged, APC labeled HEK293 Fc Inquiry
    Human IL2RA-170HP Recombinant Human IL2RA protein, Fc-tagged, R-PE labeled HEK293 Fc Inquiry
    Human IL2RA-2025H Recombinant Human IL2RA protein, His-tagged HEK293 His Inquiry
    Human IL2RA-5197H Recombinant Human IL2RA Protein E.coli N/A Inquiry
    Human IL2RA-5198H Recombinant Human IL2RA Protein HEK293 N/A Inquiry
    Human IL2RA-5199H Recombinant Human IL2RA Protein Wheat Germ N/A Inquiry
    Human IL2RA-636HA Recombinant Human IL2RA protein, Fc-tagged, APC labeled HEK293 Fc Inquiry
    Human IL2RA-636HP Recombinant Human IL2RA protein, Fc-tagged, R-PE labeled HEK293 Fc Inquiry
    Rat IL2RA-942R Recombinant Rat IL2RA Protein (Met1-Gln235), His-tagged Insect Cell His Inquiry
    CBCRY33 Interleukin-2 with its alpha Receptor E.coli N/A Inquiry
    Human CDA085P Recombinant Human CD-25 E.coli N/A Inquiry

    IL2RA involved in several pathways and played different roles in them. We selected most pathways IL2RA participated on our site, such as Cytokine-cytokine receptor interaction, Endocytosis, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL2RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IL2RA; IFNA4; LTBR; PDGFAA; GM13305; CXCL9; IL1R1; IFNA16; TNFRSF25; CXCL16
    Endocytosis BF1; CHMP4C; RAB5AB; CAPZA3; LDLRAP1A; TGFBR1B; RLN1; VPS26BL; ZFYVE20; CXCR4B
    PIK-Akt signaling pathway HSP90B1; GNB4; EIF4E2; LAMA5; TCL1; RXRA; GNG11; GYS2; DDIT4; GNG13
    Jak-STAT signaling pathway PTPN11A; GH2; IFNA8; IL21R; IL5RA; MCL1; AKT3A; IL17D; LEPR; SOCS3
    Hematopoietic cell lineage CR1; CSF1R; GYPA; CD37; CD5; CD1B; ITGA2; CD14; Il4ra; CD1d1
    Measles IL2RG; IRF7; MAVS; PIK3CD; CCNE2; STAT5B; FYN; FCGR2B; RAB9A; IFNA8
    HTLV-I infection EP300; ETS2; XIAP; HLA-DRB3; EGR2; RANBP1; HLA-DMB; KAT2B; PTTG1; LCK

    IL2RA has several biochemical functions, for example, drug binding, interleukin-2 binding, interleukin-2 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL2RA itself. We selected most functions IL2RA had, and list some proteins which have the same functions with IL2RA. You can find most of the proteins on our site.

    Function Related Protein
    drug binding NAMPT; PYGL; SRP54A; PDE2A; PNP; GPR30; SFRP1; FOLR1; GSTP2; DRD3
    interleukin-2 binding IL2RB; IL2RG; IL2RA
    interleukin-2 receptor activity IL2RB; IL2RA

    IL2RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL2RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL2RA.

    PASK

    Oliveira, PRS; Dessein, H; et al. IL2RA Genetic Variants Reduce IL-2-Dependent Responses and Aggravate Human Cutaneous Leishmaniasis. JOURNAL OF IMMUNOLOGY 194:2664-2672(2015).
    Savilova, AM; Chulkina, MM; et al. Expression of Immunomodulator Gene mRNA in Co-Culture of Mesenchymal Stromal Cells from the Placenta and Human Mononuclear Blood Cells. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE 158:561-565(2015).

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