Recombinant Human IL2RA protein, His-tagged

• Cat.No.: IL2RA-99H
• Product Overview: Recombinant Human IL2RA(22-213 aa) fused with His tag was expressed in E. coli.

Specification

• Description: IL2-Ra is one of the three constituent subunits of the IL2 receptor.IL-2Ra is released into the serum after increased cellular expression such as increased activation of B and T cells. Clinical manifestations of IL2-Ra elevation include autoimmune conditions and some leukemias and lymphomas.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Supplied in 1x PBS and 50% glycerol pH 7.4.
• Purity: Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
• Stability: Store at 4 centigrade if entire vial will be used within 2-4 weeks.Store, frozen at -20 centigrade for longer periods of time.Please avoid freeze thaw cycles.

Gene Information

• Gene Name: IL2RA interleukin 2 receptor, alpha [ Homo sapiens ]
• Official Symbol: IL2RA
• Synonyms: IL2RA; interleukin 2 receptor, alpha; IL2R; interleukin-2 receptor subunit alpha; CD25; p55; IL2-RA; IL-2-RA; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha; TCGFR; IDDM10
• Gene ID: 3559
• mRNA Refseq: NM_000417
• Protein Refseq: NP_000408
• MIM: 147730
• UniProt ID: P01589
• Chromosome Location: 10p15-p14
• Pathway: Arf6 trafficking events, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem
• Function: drug binding; interleukin-2 binding; interleukin-2 receptor activity; receptor activity