Recombinant Mouse Adam17 protein, His-tagged
Cat.No. : | Adam17-522M |
Product Overview : | Recombinant Mouse Adam17 protein(Pro 18 - Asp 563), fused with His tag, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM MES, 150 mM NaCl, pH6.5. Normally trehalose is added as protectant before lyophilization. |
Molecular Mass : | This protein carries a polyhistidine tag at the C-terminus.The protein has a calculated MW of 63.4 kDa. The protein migrates as 19 kDa and 20 kDa (Propeptide), 55-66 kDa (Mature-ADAM17) and 75-94 kDa (Pro-ADAM17) under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein Length : | Pro 18 - Asp 563 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Adam17 a disintegrin and metallopeptidase domain 17 [ Mus musculus ] |
Official Symbol : | Adam17 |
Synonyms : | ADAM17; a disintegrin and metallopeptidase domain 17; disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloprotease domain 17; Tace; CD156b; |
Gene ID : | 11491 |
mRNA Refseq : | NM_009615 |
Protein Refseq : | NP_033745 |
Products Types
◆ Recombinant Protein | ||
Adam17-308M | Recombinant Mouse Adam17 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAM17-085M | Recombinant Mouse ADAM17 Protein, His-tagged | +Inquiry |
ADAM17-157R | Recombinant Rat ADAM17 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAM17-073R | Recombinant Rat ADAM17 Protein, His-tagged | +Inquiry |
Adam17-8788R | Active Recombinant Rat Adam17 protein(Met1-Asp563), His-tagged | +Inquiry |
◆ Lysates | ||
ADAM17-1198RCL | Recombinant Rat ADAM17 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0049 | ADAM17 Inhibitor Screening Assay Kit | +Inquiry |
Kit-0048 | ADAM17 fluorometric drug discovery Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (10)
Ask a questionADAM17 is a negative regulator of the RAS system.
Yes, we have produced ADAM17 protein of this purity.
ADAM17 protein can cleave IL6R, TNFR1, ACE2, etc.
ADAM17 is widely expressed in somatic and immune cells
ADAM17 is also currently being used in studies of breast cancer and gastric cancer, etc.
ADAM17 is an activator that mediates the EGFR-PI3K-AKT pathway.
The product manual will contain relevant content on product handling, and you can also consult our technical experts on related issues.
Yes, ADAM17 protein is involved in this promotion.
ADAM17 acts as an activator of Notch pathway by mediating the of cleavage of Notch.
Addition of His tags usually does not affect the function, properties of the target protein.
Customer Reviews (3)
Write a reviewCheap price, high quality products, worth buying again
The high quality of the purchased protein helped me to obtain satisfactory experimental results.
Good after-sales service attitude, helped me solve a lot of problems in the experiment.
Ask a Question for All Adam17 Products
Required fields are marked with *
My Review for All Adam17 Products
Required fields are marked with *
Inquiry Basket