Recombinant Full Length Human Disintegrin And Metalloproteinase Domain-Containing Protein 17(Adam17) Protein, His-Tagged
Cat.No. : | RFL-25931HF |
Product Overview : | Recombinant Full Length Human Disintegrin and metalloproteinase domain-containing protein 17(ADAM17) Protein (P78536) (215-824aa), fused to N-terminal His tag, was expressed in E. coli. |
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Source : | E.coli expression system |
Species : | Homo sapiens (Human) |
Tag : | His |
Form : | Lyophilized powder |
Protein length : | Full Length of Mature Protein (215-824) |
AA Sequence : | RADPDPMKNTCKLLVVADHRFYRYM GRGEESTTTNYLIELIDRVDDIYRN TSWDNAGFKGYGIQIEQIRILKSPQ EVKPGEKHYNMAKSYPNEEKDAWDV KMLLEQFSFDIAEEASKVCLAHLFT YQDFDMGTLGLAYVGSPRANSHGGV CPKAYYSPVGKKNIYLNSGLTSTKN YGKTILTKEADLVTTHELGHNFGAE HDPDGLAECAPNEDQGGKYVMYPIA VSGDHENNKMFSNCSKQSIYKTIES KAQECFQERSNKVCGNSRVDEGEEC DPGIMYLNNDTCCNSDCTLKEGVQC SDRNSPCCKNCQFETAQKKCQEAIN ATCKGVSYCTGNSSECPPPGNAEDD TVCLDLGKCKDGKCIPFCEREQQLE SCACNETDNSCKVCCRDLSGRCVPY VDAEQKNLFLRKGKPCTVGFCDMNG KCEKRVQDVIERFWDFIDQLSINTF GKFLADNIVGSVLVFSLIFWIPFSI LVHCVDKKLDKQYESLSLFHPSNVE MLSSMDSASVRIIKPFPAPQTPGRL QPAPVIPSAPAAPKLDHQRMDTIQE DPSTDSHMDEDGFEKDPFPNSSTAA KSFEDLTDHPVTRSEKAASFKLQRQ NRVDSKETEC |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Applications : | SDS-PAGE |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Gene Name : | ADAM17 |
Synonyms : | ADAM17; CSVP; TACE; Disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; Snake venom-like protease; TNF-alpha convertase; TNF-alpha-converting enzyme; CD antigen CD156b |
UniProt ID : | P78536 |
Gene Name : | ADAM17 |
Synonyms : | ADAM17; CSVP; TACE; Disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; Snake venom-like protease; TNF-alpha convertase; TNF-alpha-converting enzyme; CD antigen CD156b |
UniProt ID : | P78536 |
Products Types
◆ Recombinant Protein | ||
ADAM17-157R | Recombinant Rat ADAM17 Protein, His (Fc)-Avi-tagged | +Inquiry |
Adam17-8788R | Active Recombinant Rat Adam17 protein(Met1-Asp563), His-tagged | +Inquiry |
ADAM17-073R | Recombinant Rat ADAM17 Protein, His-tagged | +Inquiry |
ADAM17-085M | Recombinant Mouse ADAM17 Protein, His-tagged | +Inquiry |
Adam17-308M | Recombinant Mouse Adam17 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ADAM17-1198RCL | Recombinant Rat ADAM17 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0049 | ADAM17 Inhibitor Screening Assay Kit | +Inquiry |
Kit-0048 | ADAM17 fluorometric drug discovery Kit | +Inquiry |
Related Gene
Not For Human Consumption!
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Customer Reviews (3)
Write a reviewCheap price, high quality products, worth buying again
The high quality of the purchased protein helped me to obtain satisfactory experimental results.
Good after-sales service attitude, helped me solve a lot of problems in the experiment.
Q&As (10)
Ask a questionADAM17 is a negative regulator of the RAS system.
Yes, we have produced ADAM17 protein of this purity.
ADAM17 protein can cleave IL6R, TNFR1, ACE2, etc.
ADAM17 is widely expressed in somatic and immune cells
ADAM17 is also currently being used in studies of breast cancer and gastric cancer, etc.
ADAM17 is an activator that mediates the EGFR-PI3K-AKT pathway.
The product manual will contain relevant content on product handling, and you can also consult our technical experts on related issues.
Yes, ADAM17 protein is involved in this promotion.
ADAM17 acts as an activator of Notch pathway by mediating the of cleavage of Notch.
Addition of His tags usually does not affect the function, properties of the target protein.
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