Recombinant Human Tumor Necrosis Factor Receptor Superfamily, Member 9, His-tagged

• Cat.No.: TNFRSF9-5598H
• Product Overview: Recombinant humanTNFRSF9 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques.

Specification

• Cat. No.: TNFRSF9-5598H
• Description: TNFRSF9, also knownas CD137 or ILA, is a member of the TNF superfamily of receptors. Thisprotein is mainly expressed on the surface of a variety of T cells, but alsofound in B cells, monocytes, and various transformed cell lines. TNFRSF9 isexpressed on activated T cells and binds an inducible ligand that is found onB cells, macrophages and dendritic cells.
• Source: E. coli
• Species: Human
• Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT.
• Molecular Weight: 20 kDa (193aa),confirmed by MALDI-TOF.
• Purity: > 90% by SDS - PAGE.
• Concentration: 0.5 mg/ml(determined by Bradford assay).
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSMFERTRS LQDPCSNCPA GTFCDNNRNQ ICSPCPPNSF SSAGGQRTCD ICRQCKGVFRTRKECSSTSN AECDCTPGFH CLGAGCSMCE QDCKQGQELT KKGCKDCCFG TFNDQKRGIC RPWTNCSLDGKSVLVNGTKE RDVVCGPSPA DLSPGASSVT PPAPAREPGH SPQ
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
• OfficialSymbol: TNFRSF9

Gene Information

• Gene Name: TNFRSF9 tumor necrosis factorreceptor superfamily, member 9 [ Homo sapiens ]
• Synonyms: TNFRSF9; tumornecrosis factor receptor superfamily, member 9; ILA; 4-1BB; CD137;CDw137;tumor necrosis factor receptor superfamily member 9; CD137 antigen; Tcell antigen ILA; T-cell antigen ILA; 4-1BB ligand receptor; homolog of mouse4-1BB; receptor protein 4-1BB; T-cell antigen 4-1BB homolog; induced bylymphocyte activation (ILA); interleukin-activated receptor, homolog of mouseLy63
• Gene ID: 3604
• mRNA Refseq: NM_001561
• Protein Refseq: NP_001552
• MIM: 602250
• UniProt ID: Q07011
• Chromosome Location: 1p36
• Pathway: Cytokine-cytokinereceptor interaction; Downstream signaling in naive CD8+ T cells
• Function: binding; receptoractivity