"FASTK" Related Products

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Recombinant Human FASTK (Active), GST-tagged

Cat.No.: FASTK-1402H
Product Overview: Recombinant full-length human FASTK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: FASTK or Fas-Activated Serine/Threonine Kinase is a member of the serine/threonine protein kinase family that becomes rapidly activated during Fas-mediated apoptosis in Jurkat cells and in response to Fas receptor ligation. FASTK interacts with and phosphorylates TIA1 which is an apoptosis-promoting nuclear RNA-binding protein. FAST K influences alternative pre-mRNA splicing by affecting the activity of TIA-1/TIAR. FASTK is a strong inducer of lymphocyte apoptosis. FASTK is the component of the molecular cascade that involved in FAS-mediated apoptosis. FASTK is highly expreesed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.
Source: Sf9 Cells
Species: Human
Tag: GST
Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity: 1.0 nmol/min/mg
Molecular Mass: ~84 kDa
Protein length: Full length
Purity: >70%
Applications: Kinase Assay, Western Blot
Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration: 0.1μg/μl
Gene Name: FASTK Fas-activated serine/threonine kinase [ Homo sapiens ]
Official Symbol: FASTK
Synonyms: FASTK; Fas-activated serine/threonine kinase; fas-activated serine/threonine kinase; FAST; FAST kinase;
Gene ID: 10922
mRNA Refseq: NM_006712
Protein Refseq: NP_006703
MIM: 606965
UniProt ID: Q14296
Chromosome Location: 7q35
Function: ATP binding; Fas-activated serine/threonine kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity;

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