Cat.No.: |
FASTK-1402H |
Product Overview: |
Recombinant full-length human FASTK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
Description: |
FASTK or Fas-Activated Serine/Threonine Kinase is a member of the serine/threonine protein kinase family that becomes rapidly activated during Fas-mediated apoptosis in Jurkat cells and in response to Fas receptor ligation. FASTK interacts with and phosphorylates TIA1 which is an apoptosis-promoting nuclear RNA-binding protein. FAST K influences alternative pre-mRNA splicing by affecting the activity of TIA-1/TIAR. FASTK is a strong inducer of lymphocyte apoptosis. FASTK is the component of the molecular cascade that involved in FAS-mediated apoptosis. FASTK is highly expreesed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. |
Source: |
Sf9 Cells |
Species: |
Human |
Tag: |
GST |
Form: |
Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity: |
1.0 nmol/min/mg |
Molecular Mass: |
~84 kDa |
Protein length: |
Full length |
Purity: |
>70% |
Applications: |
Kinase Assay, Western Blot |
Storage: |
Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration: |
0.1μg/μl |