"CCL7" Related Products

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Recombinant Human CCL7 protein

Cat.No. : CCL7-286H
Product Overview : Recombinant Human CCL7 protein was expressed in Escherichia coli.
Description : Human CCL7, also known as monocyte chemotactic protein 3 (MCP-3), is belonging to the CC chemokine family. MCP-3 has two homogeneous MCP-1 (CCL2) and MCP-2 (CCL8). These three MCPs were found by IL-1-beta triggered human MG-63 osteosarcoma cells. CCL7 shares 71 % and 58 % a.a. sequence identity with MCP-1 and MCP-2, respectively. CCL7 has chemotactic function for monocytes and eosinophils, but not for neutrophils. In addition, it can also chemoattract activated NK cells.
Source : E.coli
Species : Human
Form : Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.
Bio-activity : Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/ml.
Molecular Mass : Approximately 9.0 kDa, a single, non-glycosylated polypeptide chain containing 76 amino acids.
Protein length : 76
AA Sequence : QPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL
Endotoxin : Less than 1 EU/μg of rHuMCP-3/CCL7 as determined by LAL method.
Purity : >97% by SDS-PAGE and HPLC analysis.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.
SDS-PAGE of CCL7-286H :

Gene Name : CCL7
Official Symbol : CCL7
Synonyms : CCL7; chemokine (C-C motif) ligand 7; SCYA6, SCYA7, small inducible cytokine A7 (monocyte chemotactic protein 3); C-C motif chemokine 7; FIC; MARC; MCP 3; MCP3; monocyte chemoattractant protein 3; monocyte chemotactic protein 3; NC28; small-inducible cytokine A7; small inducible cytokine A7 (monocyte chemotactic protein 3); MCP-3; SCYA6; SCYA7; MGC138463; MGC138465;
Gene ID : 6354
mRNA Refseq : NM_006273
Protein Refseq : NP_006264
MIM : 158106
UniProt ID : P80098

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