• Official Full Name

    chemokine (C-C motif) ligand 7

  • Overview

    Murine MCP-3, also known as Monocyte Chemotactic Protein 3 or C-C Motif Chemokine 7, is a 97 amino acid cytokine protein expressed from the Ccl7 gene located on chromosome 11. After initial synthesis and translocation, the 23 residue signal sequence is cleaved, allowing for the 74 residue MCP-3 peptide to properly fold and mature. MCP-3 is essentially a chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Moreover, the monomeric member of the intercrine beta (chemokine C-C) family tends to augment monocyte anti-tumor activity as well.
  • Synonyms

    RP23-350G1.4; MCP-3; Scya7; fic; marc; mcp3; C-C motif chemokine 7; RANTES/sis homolog; intercrine/chemokine MARC; monocyte chemoattractant protein 3; monocyte chemotactic protein 3; small inducible cytokine A7; small-inducible cytokine A7;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • CHO
  • E.coli
  • HEK293
  • Human
  • Human Cell
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Biotin
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
  • Strep II
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCL7-385H Active Recombinant Human Chemokine (C-C Motif) Ligand 7, HIgG1 Fc-tagged CHO Fc
Human CCL7-132H Active Recombinant Human CCL7, biotinylated E.coli Biotin
Human CCL7-384H Active Recombinant Human Chemokine (C-C Motif) Ligand 7, HIgG1 Fc-tagged, mutant CHO Fc
Human CCL7-383H Active Recombinant Human Chemokine (C-C Motif) Ligand 7, MIgG2a Fc-tagged CHO Fc
Human CCL7-069C Active Recombinant Human CCL7 Protein (76 aa) E.coli 76
Human CCL7-36H Recombinant Human Chemokine (C-C Motif)Ligand 7 E.coli N/A
Human CCL7-291H Recombinant Human CCL7, StrepII-tagged Human Cell Strep II 24-99, 76 a.a.
Human CCL7-29150TH Recombinant Human CCL7 E.coli N/A
Human CCL7-199H Recombinant Human Chemokine (C-C Motif) Ligand 7, His-tagged Human His
Human CCL7-10852H Recombinant Human CCL7, His-tagged E.coli His 1-109a.a.
Human CCL7-286H Recombinant Human CCL7 protein E.coli N/A 76
Human CCL7-696H Recombinant Human CCL7 protein, GST-tagged E.coli GST Gln24~Leu99 (Accession # P80098)
Human CCL7-627H Recombinant Human CCL7 protein, His-tagged HEK293 His Gln 24 - Leu 99
Human CCL7-0643H Recombinant Human CCL7 Protein, GST-Tagged Wheat Germ GST
Human CCL7-194H Recombinant Human CCL7 protein E.coli N/A
Human CCL7-170HCL Recombinant Human CCL7 lysate HEK293 N/A
Human CCL7-72H Recombinant Human CCL7 Protein E.coli 76 amino acid
Human CCL7-31H Recombinant Human CCL7 Protein E.coli
Human CCL7-151H Recombinant Human CCL7 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human CCL7-0889H Recombinant Human CCL7 Protein (Gln24-Leu99), N-His tagged E.coli N-His Gln24-Leu99
Human CCL7-2955HF Recombinant Full Length Human CCL7 Protein, GST-tagged In Vitro Cell Free System GST 99 amino acids
Human CCL7-025H Recombinant Human CCL7 Protein 99
Human CCL7-226C Active Recombinant Human CCL7 Protein (76 aa) CHO 76
Human CCL7-628H Recombinant Human CCL7 protein (Gln 24-Leu 99), His-tagged E.coli His
Human CCL7-176H Recombinant Human CCL7 Protein, Mature chain, Tag Free, Biotinylated E.coli Tag Free Mature chain
Human CCL7-80H Recombinant Human CCL7 Protein, Biotin-tagged E.coli Biotin
Human CCL7-026H Recombinant Human CCL7 Protein, Biotinylated 99
Mouse Ccl7-287M Active Recombinant Mouse Chemokine (C-C motif) Ligand 7 E.coli N/A
Mouse CCL7-46M Recombinant Mouse chemokine (C-C motif) ligand 7 (CCL7) E.coli N/A
Mouse Ccl7-618M Recombinant Mouse Ccl7 protein E.coli N/A 74
Mouse Ccl7-883M Recombinant Mouse Ccl7 protein, His-tagged E.coli His Gln24-Pro97
Mouse Ccl7-5245M Recombinant Mouse Ccl7 protein, His-tagged E.coli His 28-97aa
Mouse Ccl7-002M Active Recombinant Mouse Ccl7 Protein E.coli
Mouse CCL7-32M Recombinant Mouse CCL7 Protein E.coli
Mouse Ccl7-225C Active Recombinant Mouse Ccl7 Protein (74 aa) CHO 74
Mouse Ccl7-2041M Active Recombinant Mouse Ccl7 Protein E.coli Gln24-Pro97
Rat Ccl7-635R Recombinant Rat Ccl7 protein E.coli N/A 74
Rat CCL7-1216R Recombinant Rat CCL7 Protein Mammalian Cell His
Rat Ccl7-697R Recombinant Rat Ccl7 protein, His & T7-tagged E.coli His/T7 Gln24~Pro97 (Accession # Q9QXY8)
Rat CCL7-874R-B Recombinant Rat CCL7 Protein Pre-coupled Magnetic Beads HEK293
Rat CCL7-874R Recombinant Rat CCL7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CCL7-33R Recombinant Rat CCL7 Protein E.coli
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CCL7 involved in several pathways and played different roles in them. We selected most pathways CCL7 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL20RB;IL17A;Ifnlr1;TNFRSF10B;IL22RA1;IL25;IL12RB1;CCL25;VEGFB
Chemokine signaling pathwayFGR;CXCR5;CXCL6;RAC2;CXCL9;RAP1B;CXCL8;GNB2;VAV3

CCL7 has several biochemical functions, for example, CCR1 chemokine receptor binding, CCR2 chemokine receptor binding, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL7 itself. We selected most functions CCL7 had, and list some proteins which have the same functions with CCL7. You can find most of the proteins on our site.

Function Related Protein
CCR1 chemokine receptor bindingCCL4;CCL3;CCL5;CCL23;CREB3;CCL7
CCR2 chemokine receptor bindingCCL7;Ccl12;CCL2
chemokine activityCXCL19;PPBP;CXCL20;CCL34B.9;CCL5;CCL26;CXCL5;CXCL9;CCL16
heparin bindingKAL1;SLIT1;TENM1;GREM2;ZNF146;FGF2;FGFR1A;COL20A1;APP

CCL7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL7.


Gene Family

Chemokines Cytokines

Research Area

Related articles

Kitase, Y; Lee, S; et al. CCL7 Is a Protective Factor Secreted by Mechanically Loaded Osteocytes. JOURNAL OF DENTAL RESEARCH 93:1108-1115(2014).
Mercer, PF; Williams, AE; et al. Proteinase-Activated Receptor-1, CCL2, and CCL7 Regulate Acute Neutrophilic Lung Inflammation. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 50:144-157(2014).
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