ccl7
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  • Official Full Name
  • chemokine (C-C motif) ligand 7
  • Background
  • Murine MCP-3, also known as Monocyte Chemotactic Protein 3 or C-C Motif Chemokine 7, is a 97 amino acid cytokine protein expressed from the Ccl7 gene located on chromosome 11. After initial synthesis and translocation, the 23 residue signal sequence is cleaved, allowing for the 74 residue MCP-3 peptide to properly fold and mature. MCP-3 is essentially a chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Moreover, the monomeric member of the intercrine beta (chemokine C-C) family tends to augment monocyte anti-tumor activity as well.
  • Synonyms
  • RP23-350G1.4; MCP-3; Scya7; fic; marc; mcp3; C-C motif chemokine 7; RANTES/sis homolog; intercrine/chemokine MARC; monocyte chemoattractant protein 3; monocyte chemotactic protein 3; small inducible cytokine A7; small-inducible cytokine A7
Cat.#:CCL7-0643HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCL7 Protein, GST-Tagged
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Cat.#:CCL7-199HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chemokine (C-C Motif) Ligand 7, His-tagged
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Cat.#:CCL7-286HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chemokine (C-C Motif) Ligand 7
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Cat.#:Ccl7-287MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Chemokine (C-C motif) Ligand 7
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Cat.#:CCL7-10852HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL7, His-tagged
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Cat.#:CCL7-132HTag:Biotin
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL7, biotinylated
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Cat.#:CCL7-194HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL7 protein
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Cat.#:CCL7-29150THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL7
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Cat.#:CCL7-291HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human CCL7, StrepII-tagged
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Cat.#:CCL7-383HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-C Motif) Ligand 7, MIgG2a Fc-tagged
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Cat.#:CCL7-384HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-C Motif) Ligand 7, HIgG1 Fc-tagged, mutant
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Cat.#:CCL7-385HTag:Fc
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Chemokine (C-C Motif) Ligand 7, HIgG1 Fc-tagged
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Cat.#:CCL7-627HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL7, His tagged
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Cat.#:CCL7-696HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CCL7 protein, GST-tagged
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Cat.#:Ccl7-618MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ccl7
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Cat.#:Ccl7-883MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ccl7 Protein, His-tagged
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Cat.#:CCL7-1216RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CCL7 Protein
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Cat.#:Ccl7-635RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ccl7
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Cat.#:Ccl7-697RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ccl7 protein, His & T7-tagged
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Cat.#:CCL7-36HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Chemokine (C-C Motif)Ligand 7
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Cat.#:CCL7-46MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse chemokine (C-C motif) ligand 7 (CCL7)
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Cat.#:CCL7-170HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human CCL7 lysate
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Involved Pathway

CCL7 involved in several pathways and played different roles in them. We selected most pathways CCL7 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
IL8L1; TNFRSF13C; CTF1; TNFRSF4; IL17A; NGFRB; CSF3; LEPB; CXCL9; EPOR
Chemokine signaling pathway
PLCB1; STAT2; NCF1; RASGRP2; CRKL; CCL3L3; CX3CL1; CCL4L1; CXCR1; ITK

Protein Function

CCL7 has several biochemical functions, for example, CCR1 chemokine receptor binding, CCR2 chemokine receptor binding, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL7 itself. We selected most functions CCL7 had, and list some proteins which have the same functions with CCL7. You can find most of the proteins on our site.
Function
Related Protein
Function CCR1 chemokine receptor binding
Related Protein CCL3; CCL4; CCL23; CCL5; CREB3; CCL7
Function CCR2 chemokine receptor binding
Related Protein Ccl12; CCL2; CCL7
Function chemokine activity
Related Protein CCL25; CXL34B.11; Cxcl15; CCL14; CCL21; CCL18; AMCF-II; CCL38.1; CXCL12A; CCL19A.1
Function heparin binding
Related Protein NRP2; LXN; RPL29; PRG2; BMP7; FGF10; NELL2; VEGFB; VEGFAB; NAV2
Function protein binding
Related Protein NAA35; GBF1; PSMC4; DDB1; VWF; DOCK9; LIMS3L; MAP4K1; RGS6; CEP55

Interacting Protein

CCL7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL7.
UBQLN1; UBQLN1; AES; FEZ1

CCL7 Related Articles

Kitase, Y; Lee, S; et al. CCL7 Is a Protective Factor Secreted by Mechanically Loaded Osteocytes. JOURNAL OF DENTAL RESEARCH 93:1108-1115(2014).
Mercer, PF; Williams, AE; et al. Proteinase-Activated Receptor-1, CCL2, and CCL7 Regulate Acute Neutrophilic Lung Inflammation. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 50:144-157(2014).

CCL7 Related Gene Family

Chemokines Cytokines