"IL2" Related Products

Recombinant Human IL2

Cat. No.: IL2-341H
Product Overview: Human IL2 (NP_000577, 22 a.a.-153 a.a.) partial recombinant protein expressed in Escherichia coli.
Description: Interleukin-2 (IL-2) is an interleukin, a type of cytokine immune system signaling molecule, which is a leukocytotrophic hormone that is instrumental in the body"s natural response to microbial infection and in discriminating between foreign (non-self) and self. IL-2 mediates its effects by binding to IL-2 receptors, which are expressed by lymphocytes, the cells that are responsible for immunity.
Sequence: MPTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR WITFSQSIIS TLT
Theoretical MW (kDa): 15.4
Form: Liquid
Preparation Method: Escherichia coli expression system
Purity: > 95% by SDS-PAGE
Activity: Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells. The ED50 for this effect is < 1.5 ng/mL.
Application: SDS-PAGE
Storage Buffer: In PBS, pH 7.4
Storage: Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing.
Unitprot ID: P60568
Pathways: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; T cell receptor signaling pathway; Type I diabetes mellitus
Gene Name: IL2 interleukin 2 [ Homo sapiens ]
Official Symbol: IL2
Synonyms: IL-2; TCGF; lymphokine; T-cell growth factor; Aldesleukin, Interleukin-2; interleukin-2 precursor; involved in regulation of T-cell clonal expansion; IL2; interleukin 2
Gene ID: 3558
mRNA Refseq: NM_000586
Protein Refseq: NP_000577
MIM: 147680
Chromosome Location: 4q26-q27
Function: interleukin-2 receptor binding; kinase activator activity

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