Recombinant Human E1A Binding Protein P300, GST-tagged
Cat.No. : | EP300-1584H |
Product Overview : | Recombinant human EP300 (532-1153; contains the catalytic domain) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | EP300-1584H |
Description : | EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein that functions as a histone acetyltransferase. EP300 regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. EP300 binding is a highly accurate process and can be used for identifying enhancers and their associated activities. EP300 is also useful in the study of the role of tissue-specific enhancers in human biology and diseases on a genome wide scale. Defects in EP300 gene are a cause of Rubinstein-Taybi syndrome that play a important role in epithelial cancer and act as a classic tumor suppressor gene. |
Applications : | Western Blot |
Molecular Weight : | 120 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50 mM Tris-HCl, ph 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol. |
Purity : | > 80 % |
Concentration : | 0.1 ug/ul |
Sequences : | 532-1153; contains the catalytic domain |
Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | ATF-2 transcription factor network; Adherens junction; Androgen Receptor Signaling Pathway; C-MYB transcription factor network; Cell cycle; Delta-Notch Signaling Pathway; Diabetes pathways; Direct p53 effectors; E2F transcription factor network; Energy Metabolism; FOXA1 transcription factor network; FOXM1 transcription factor network; Influenza A; Melanogenesis; Regulation of Wnt-mediated beta catenin signaling and target gene transcription |
Gene Name : | EP300 E1A binding protein p300 [ Homo sapiens ] |
Official Symbol : | EP300 |
Synonyms : | EP300; E1A binding protein p300; p300; KAT3B; RSTS2; histone acetyltransferase p300; p300 HAT; E1A-binding protein, 300Kd; E1A-associated protein p300; OTTHUMP00000198754 |
Gene ID : | 2033 |
mRNA Refseq : | NM_001429 |
Protein Refseq : | NP_001420 |
MIM : | 602700 |
UniProt ID : | Q09472 |
Chromosome Location : | 22q13.2 |
Function : | DNA binding; NF-kappaB binding; RNA polymerase II activating transcription factor binding; SMAD binding; acetyltransferase activity; activating transcription factor binding; acyltransferase activity; bHLH transcription factor binding; glucocorticoid receptor binding; histone acetyltransferase activity; metal ion binding; peroxisome proliferator activated receptor binding; transcription coactivator activity; contributes_to transcription coactivator activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
EP300-1306R | Recombinant Rhesus Macaque EP300 Protein, His (Fc)-Avi-tagged | +Inquiry |
EP300-02H | Recombinant Human EP300 Protein, N-Flag-tagged | +Inquiry |
EP300-43H | Recombinant Human EP300 Protein, GST-tagged | +Inquiry |
EP300-12H | Recombinant Human EP300 Protein (bromodomain, 1041-1161), N-His and C-Flag-tagged | +Inquiry |
EP300-3346H | Recombinant Human EP300 Protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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