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Active Recombinant Rat Uchl1 protein(Glu2-Ala223), His-tagged

Cat.No. : Uchl1-1809R
Product Overview : Recombinant Rat UCHL1 (Q00981) (Glu 2-Ala 223) was expressed in E. coli, fused with a polyhistidine tag at the N-terminus.
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  • Gene Information
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Source : E. coli
Species : Rat
Tag : N-His
Protein length : Glu2-Ala223
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : Measured by the hydrolysis of UbiquitinAMC. The specific activity is >100 pmoles/min/μg.
Molecular Mass : The recombinant Rat UCHL1 comprises 233 amino acids and predicts a molecular mass of 26.2 kDa. The apparent molecular mass of the Rat UCHL1 is approximately 28 kDa in SDS-PAGE under reducing conditions.
Purity : > 97 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Uchl1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) [ Rattus norvegicus ]
Official Symbol : Uchl1
Synonyms : UCHL1; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L1; PGP9.5; UCH-L1; PGP 9.5; ubiquitin thioesterase L1; neuron cytoplasmic protein 9.5; ubiquitin carboxy-terminal hydrolase L1;
Gene ID : 29545
mRNA Refseq : NM_017237
Protein Refseq : NP_058933

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can UCHL1 be used in the early diagnosis of neurodegenerative diseases? 10/19/2021

Early research suggests that changes in UCHL1 levels may be detected in the early stages of some neurodegenerative diseases, but more studies are needed for validation.

Is UCHL1 exclusively associated with neurological functions? 11/22/2019

While UCHL1 is primarily associated with neurological functions, it also has roles in non-neuronal tissues, including certain types of cancer cells.

What are the challenges in using UCHL1 as a diagnostic marker? 09/25/2019

Challenges include the need for standardized assays, variations in UCHL1 levels among individuals, and the influence of other factors on its expression.

Can UCHL1 levels serve as a biomarker for neurodegenerative diseases? 11/22/2017

Yes, elevated or decreased levels of UCHL1 in cerebrospinal fluid or blood may serve as potential biomarkers for certain neurological disorders.

What other conditions or diseases are associated with UCHL1 dysfunction? 07/05/2016

UCHL1 dysfunction has been implicated in conditions such as certain cancers and ischemic stroke.

Customer Reviews (3)

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01/22/2021

    Whether it is regarding experimental design, optimization of protocols, or troubleshooting issues, their expertise and prompt customer service help researchers overcome challenges efficiently.

    11/10/2018

      They provide comprehensive technical assistance and guidance throughout the entire research process.

      01/24/2018

        Heir responsiveness to inquiries and willingness to address concerns contribute to a smooth and productive research experience.

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