Active Recombinant Human BMP2
Cat.No. : | BMP2-23H |
Product Overview : | Recombinant, human bone morphogenetic protein-2(BMP-2) expressed in CHO cell and purified byproprietary chromatographic methods. |
- Specification
- Gene Information
- Related Products
Description : | BMP-2 is a homodimeric protein that belongs to the transforming growth factor β (TGF-β) superfamily. BMP-2 is known to regulate diverse fundamental processes during embryonic development. BMP-2 have also been shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. |
Source : | CHO Cells |
Species : | Human |
Form : | Lyophilized from a 0.2 μm filtered solution in 0.2% sucrose, 2.5% Glycine, 0.01% polysorbate 80, 0.01%sodium chloride, 3% mannitol per 1 μg of BMP-2. |
Bio-activity : | The ED50 as determined by cytolysis of ATDC-5 cell is less than 50 ng/ml. |
Molecular Mass : | The molecule has a calculated molecular mass of approximately 26 kDa. Due to glycosylation, rhBMP-2migrates as an approximately 36 kDa protein under non-reducing conditions and as a 17 - 18 kDa proteinunder reducing conditions in SDS-PAGE. |
Endotoxin : | <0.5 eu per 1 μg of bmp-2 as determined by the lal</0.5 |
Purity : | >95% as determined by SEC-HPLC and SDS-PAGE. |
Storage : | Lyophilized samples are stable for up to six months at -20° C to -70° C. |
Reconstitution : | Reconstitute to 100 μg/mL with sterile distilled water. Further dilutions can be made in aqueous buffersjust prior to use. |
Gene Name : | BMP2 bone morphogenetic protein 2 [ Homo sapiens ] |
Official Symbol : | BMP2 |
Synonyms : | BMP2; bone morphogenetic protein 2; BMP2A; BMP-2A; bone morphogenetic protein 2A; BDA2; |
Gene ID : | 650 |
mRNA Refseq : | NM_001200 |
Protein Refseq : | NP_001191 |
MIM : | 112261 |
UniProt ID : | P12643 |
Chromosome Location : | 20p12 |
Pathway : | Adipogenesis, organism-specific biosystem; BMP Signalling Pathway, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Heart Development, organism-specific biosystem; |
Function : | BMP receptor binding; SMAD binding; activin receptor activity, type II; cytokine activity; growth factor activity; phosphatase activator activity; protein binding; protein domain specific binding; protein heterodimerization activity; protein homodimerization activity; receptor binding; retinol dehydrogenase activity; transmembrane receptor protein serine/threonine kinase activity; |
Products Types
◆ Lysates | ||
BMP2-3075HCL | Recombinant Human BMP2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Ask a questionCustomer Reviews (5)
Write a reviewWe have tested the recombinant protein in our ELISAs and it performs well.
I'm pleased with your recombinant products. It is done well in our experiment.
Very nice puchase experience with all of you.
I’ve used the products you provided, and they all work good in my study.
Thanks so much! Your protein performed really well,
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