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Recombinant Human late endosomal/lysosomal adaptor, MAPK and MTOR activator 2, His-tagged

Cat.No. : LAMTOR2-552H
Product Overview : LAMTOR2, 1-125aa, Human His tag, E.coli
  • Specification
  • Gene Information
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Description : LAMTOR2 is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Recombinant human LAMTOR2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source : E.coli
Species : Human
Tag : His-tag
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Molecular Mass : 15.9 kDa (148aa) confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMLRPKAL TQVLSQANTG GVQSTLLLNN EGSLLAYSGY GDTDARVTAA IASNIWAAYD RNGNQAFNED NLKFILMDCM EGRVAITRVA NLLLCMYAKE TVGFGMLKAK AQALVQYLEE PLTQVAAS
Purity : >90% by SDS - PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 0.25 mg/ml (determined by Bradford assay)
Gene Name : LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 [ Homo sapiens ]
Official Symbol : LAMTOR2
Synonyms : LAMTOR2; late endosomal/lysosomal adaptor, MAPK and MTOR activator 2; roadblock domain containing 3 , ROBLD3; ragulator complex protein LAMTOR2; ENDAP; endosomal adaptor protein; MAPBPIP; MAPKSP1 adaptor protein; MAPKSP1AP; mitogen activated protein binding protein interacting protein; p14; Ragulator2; endosomal adaptor protein p14; roadblock domain containing 3; roadblock domain-containing protein 3; late endosomal/lysosomal Mp1-interacting protein; late endosomal/lysosomal adaptor and MAPK and MTOR activator 2; mitogen-activated protein-binding protein-interacting protein (MAPBPIP); ROBLD3; HSPC003; RP11-336K24.9;
Gene ID : 28956
mRNA Refseq : NM_001145264
Protein Refseq : NP_001138736
MIM : 610389
UniProt ID : Q9Y2Q5
Chromosome Location : 1q22
Function : protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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