Recombinant Rat Csf1 Csf1-14R

Recombinant Rat Csf1

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Recombinant Rat Csf1

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Cat.No. : Csf1-14R
Product Overview : Recombinant Rat Csf1 was expressed in CHO.
Description : Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers.
Source : CHO
Species : Rat
Form : White Freeze-dried Powder. Lyophilized after extensive dialysis against PBS.
Bio-activity : ED50 < 2.5 ng/ml, measured in a cell proliferation assay using Murine M-NFS-60 cells, corresponding to a specific activity of > 4×10^5 units/mg.
Molecular Mass : 32-40 kDa, observed by non-reducing SDS-PAGE.
AA Sequence : EVSEHCSHMI GNGHLQILQQ LIDSQMETAC LIEYKFVDQEQLDDPVCYLK KAFVLVQVII EETMRFKDNT PNANATERLQELSMKLNSCF IKDYKEQNEA CVQTYKESPL RLLEKIKNFFNETKNFLEKD WNIFSKNCND SLAKCSSRDV VTKP
Endotoxin : < 0.2 EU/μg, determined by LAL method.
Purity : > 95% as analyzed by SDS-PAGE.
Storage : Lyophilized recombinant Rat Macrophage-Colony Stimulating Factor (M-CSF) remains stable up to 6 months at -80 ºC from date of receipt. Upon reconstitution, rrM-CSF should be stable up to 1 week at 4 °C or up to 2 months at -20 ºC.
Reconstitution : Reconstituted in ddH2O or PBS at 100 μg/ml.
Gene Name : Csf1 colony stimulating factor 1 (macrophage) [ Rattus norvegicus (Norway rat) ]
Official Symbol : Csf1
Synonyms : Csf1; colony stimulating factor 1 (macrophage); macrophage colony-stimulating factor 1; CSF-1; MCSF; NP_076471.3; EC 2.7.10.1
Gene ID : 78965
mRNA Refseq : NM_023981
Protein Refseq : NP_076471
UniProt ID : Q8JZQ0
Chromosome Location : 2q34
Pathway : Cytokine-cytokine receptor interaction; Cytokines and Inflammatory Response (BioCarta); Hematopoietic cell lineage
Function : cytokine activity; growth factor activity; macrophage colony-stimulating factor receptor binding

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