Recombinant Human ICOSLG Protein, His-tagged ICOSLG-1027H

Recombinant Human ICOSLG Protein, His-tagged

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Recombinant Human ICOSLG Protein, His-tagged

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Cat.No. : ICOSLG-1027H
Product Overview : Recombinant Human ICOSLG (Accession # O75144) Asp19-Ser258, fused with a C-terminal 6-His tag, was produced in Human embryonic kidney cell, HEK293-derived.
Source : HEK293 Cells
Species : Human
Tag : His
Predicted N Terminal : Asp19
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its ability to co-stimulate IL-4 secretion by D10.G4.1 mouse helper T cells in the presence of anti-CD3.The ED50 for this effect is typically 0.3-1.5 µg/mL.Measured by its ability to stimulate human T cell proliferation in the presence of anti-CD3. Wang, S. et al. (2000) Blood 96:2808.The ED50 for this effect is typically 0.3-1.2 µg/mL.
Molecular Mass : Recombinant Human ICOSLG, His-tagged has a calculated MW of 28 kDa. In SDS-PAGE migrates as 59-64 kDa, reducing conditions.
Protein length : Asp19-Ser258
Purity : >95%, by SDS-PAGE with silver staining.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : ICOSLG inducible T-cell co-stimulator ligand [ Homo sapiens ]
Official Symbol : ICOSLG
Synonyms : ICOSLG; inducible T-cell co-stimulator ligand; ICOSL; ICOS ligand; B7 homolog 2; B7 homologue 2; B7 H2; B7 related protein 1; B7H2; B7RP 1; B7RP1; CD275; GL50; ICOS L; KIAA0653; B7-like protein Gl50; B7-related protein 1; transmembrane protein B7-H2 ICOS ligand; B7-H2; LICOS; B7RP-1; ICOS-L;
Gene ID : 23308
mRNA Refseq : NM_015259
Protein Refseq : NP_056074
MIM : 605717
UniProt ID : O75144
Chromosome Location : 21q22.3

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