Recombinant Mouse ICOSLG Overexpression Lysate(Met 1-Lys 279)
Cat.No. : | ICOSLG-2618MCL |
Product Overview : | Recombinant Mouse ICOSLG Overexpression Lysate(NP_056605.1)(Met 1-Lys 279) was expressed in HEK293, fused with a polyhistidine tag at the C-terminus. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | C-His |
Protein length : | Met 1-Lys 279 |
Form : | Modified RIPA Lysis Buffer: 50 mM Tris-HCl pH 7.4, 150 mM NaCl, 1mM EDTA, 1% Triton X-100, 0.1% SDS, 1% Sodium deoxycholate, 1mM PMSF. |
Molecular Mass : | The recombinant mouse B7-H2 comprises 244 amino acids with a predicted molecular mass of 27.8 kDa. As a result of glycosylation, the apparent molecular mass of rmB7-H2 is approximately 45-55 kDa in SDS-PAGE under reducing conditions. |
Storage : | Store at 4°C for up to twelve months from date of receipt. After re-dissolution, aliquot and store at -80°C for up to twelve months. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Official Symbol : | ICOSLG |
Official Symbol : | ICOSLG |
Products Types
◆ Recombinant Protein | ||
ICOSLG-90H | Recombinant Human ICOSLG Protein, His (Fc)-Avi-tagged | +Inquiry |
ICOSLG-794H | Recombinant Human ICOSLG Protein, MYC/DDK-tagged | +Inquiry |
ICOSLG-3213HB | Recombinant Human ICOSLG protein(Met1-Ser258), His-tagged, Biotinylated | +Inquiry |
ICOSLG-039H | Recombinant Human ICOSLG Protein, His-tagged | +Inquiry |
ICOSLG-598H | Recombinant Human ICOSLG Protein | +Inquiry |
◆ Lysates | ||
ICOSLG-2804MCL | Recombinant Mouse ICOSLG Overexpression Lysate(Met 1-Lys 279) | +Inquiry |
ICOSLG-1095HCL | Recombinant Human ICOSLG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionICOSLG protein plays an important regulatory role in the immune system. It binds to ICOS receptors on the surface of T cells and promotes the activation and differentiation of T cells, which in turn affects the strength and direction of the immune response.
Certain biomolecules can serve as molecular markers of ICOSLG proteins, such as mRNAs or proteins of ICOSLG proteins detected in biological samples such as blood and urine. These markers can be used for early diagnosis of disease, prognostic judgment, or monitoring of treatment efficacy.
Factors to be considered in drug development for ICOSLG proteins include drug specificity, safety, pharmacokinetic properties, etc. In addition, the dosage form, route of administration, and dosage of the drug need to be considered to develop an effective treatment plan.
A variety of factors can affect the expression of ICOSLG protein, including cytokines, inflammatory factors, immunostimulants, etc. These factors can stimulate or inhibit the expression of ICOSLG protein, which in turn affects the strength and direction of the immune response.
Therapeutic strategies targeting ICOSLG proteins include inhibition of its activity, modulation of its expression, and gene therapy. For example, the development of small molecule inhibitors or antibody drugs against ICOSLG protein to inhibit its aberrant activity in disease, or the regulation of ICOSLG protein expression through gene knockout or overexpression technology.
Assessing the potential of ICOSLG proteins as drug targets requires a comprehensive analysis. Factors to consider include the structure and function of the ICOSLG protein, its role in the immune system, interactions with existing medications, and potential therapeutic efficacy and safety.
Customer Reviews (3)
Write a reviewICOSLG performed very well in the experiments, with reliable and reproducible results.
The stability is very strong, and it can maintain the stability of its structure and function even after a lot of use, which shows its excellent quality and reliability.
The storage conditions are simple, and it will not be denatured even at ultra-low temperatures.
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