Recombinant Human NF1 Protein, His-tagged
Cat.No. : | NF1-334H |
Product Overview : | Recombinant Human NF1 protein with His tag was expressed in E.coli. |
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- Gene Information
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Description : | This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | ~40.2 kDa, reducing conditions |
AA Sequence : | MGSSHHHHHHSSGLVPRGSHMETVL ADRFERLVELVTMMGDQGELPIAMA LANVVPCSQWDELARVLVTLFDSRH LLYQLLWNMFSKEVELADSMQTLFR GNSLASKIMTFCFKVYGATYLQKLL DPLLRIVITSSDWQHVSFEVDPTRL EPSESLEENQRNLLQMTEKFFHAII SSSSEFPPQLRSVCHCLYQVVSQRF PQNSIGAVGSAMFLRFINPAIVSPY EAGILDKKPPPRIERGLKLMSKILQ SIANHVLFTKEEHMRPFNDFVKSNF DAARRFFLDIASDCPTSDAVNHSLS FISDGNVLALHRLLWNNQEKIGQYL SSNRDHKAVGRRPFDKMATLLAYLG PPEH |
Purity : | >90%, by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 0.16 mg/mL |
Storage Buffer : | Supplied as a 0.2 μm filtered solution in 50 mM Tris-HCl, pH 7.5, 200 mM NaCl. |
Publication : |
An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development (2020)
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Gene Name : | NF1 neurofibromin 1 [ Homo sapiens (human) ] |
Official Symbol : | NF1 |
Synonyms : | NF1; neurofibromin 1; WSS; NFNS; VRNF; neurofibromin; neurofibromatosis 1; neurofibromatosis-related protein NF-1; truncated neurofibromin 1 |
Gene ID : | 4763 |
mRNA Refseq : | NM_000267 |
Protein Refseq : | NP_000258 |
MIM : | 613113 |
UniProt ID : | P21359 |
Products Types
◆ Recombinant Protein | ||
NF1-32H | Active Recombinant Human NF1 Protein (1197-1528), N-His tagged | +Inquiry |
NF1-3625R | Recombinant Rat NF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NF1-3967R | Recombinant Rat NF1 Protein | +Inquiry |
NF1-335H | Recombinant Human NF1, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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