Recombinant Human BMI1

• Cat.No.: BMI1-27486TH
• Product Overview: Recombinant full length protein of Human Bmi1 with proprietary tag; predicted MW 61.60 kDa, inclusive of tag.

Specification

• Description: BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1 gene.
• Protein length: 326 amino acids
• Molecular Weight: 61.600kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCK TCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVY KLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADE DKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVND KRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPL KDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQR DGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQ SPHPQFPHISSTMNGTSNSPSGNHQSSFANRPRKASVNGS SATSSG
• Sequence Similarities: Contains 1 RING-type zinc finger.

Gene Information

• Gene Name: BMI1 BMI1 polycomb ring finger oncogene [ Homo sapiens ]
• Official Symbol: BMI1
• Synonyms: BMI1; BMI1 polycomb ring finger oncogene; B lymphoma Mo MLV insertion region 1 homolog (mouse) , PCGF4, polycomb group ring finger 4; polycomb complex protein BMI-1; RNF51
• Gene ID: 648
• mRNA Refseq: NM_005180
• Protein Refseq: NP_005171
• MIM: 164831
• Uniprot ID: P35226
• Chromosome Location: 10p13
• Pathway: Senescence and Autophagy, organism-specific biosystem; Transcriptional misregulation in cancers, organism-specific biosystem; Transcriptional misregulation in cancers, conserved biosystem; Validated targets of C-MYC transcriptional activation, organism-specific biosystem
• Function: RING-like zinc finger domain binding; chromatin binding; metal ion binding; protein binding; ubiquitin-protein ligase activity