Recombinant Human BMI1 Protein, His tagged
Cat.No. : | BMI1-771H |
Product Overview : | Recombinant Human BMI1 Protein with His tag was expressed in E. coli. |
Availability | October 24, 2024 |
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Description : | This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | The protein has a calculated MW of 39 kDa. |
AA Sequence : | MGSSHHHHHHSSGLVPRGSHMHRTT RIKITELNPHLMCVLCGGYFIDATT IIECLHSFCKTCIVRYLETSKYCPI CDVQVHKTRPLLNIRSDKTLQDIVY KLVPGLFKNEMKRRRDFYAAHPSAD AANGSNEDRGEVADEDKRIITDDEI ISLSIEFFDQNRLDRKVNKDKEKSK EEVNDKRYLRCPAAMTVMHLRKFLR SKMDIPNTFQIDVMYEEEPLKDYYT LMDIAYIYTWRRNGPLPLKYRVRPT CKRMKISHQRDGLTNAGELESDSGS DKANSPAGGIPSTSSCLPSPSTPVQ SPHPQFPHISSTMNGTSNSPSGNHQ SSFANRPRKSSVNGSSATSSG |
Endotoxin : | < 1 EU/μg by LAL |
Purity : | > 90% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 0.15 mg/mL by BCA |
Storage Buffer : | Sterile PBS, pH 7.4 |
Gene Name : | BMI1 BMI1 polycomb ring finger oncogene [ Homo sapiens ] |
Official Symbol : | BMI1 |
Synonyms : | BMI1; BMI1 polycomb ring finger oncogene; B lymphoma Mo MLV insertion region 1 homolog (mouse), PCGF4, polycomb group ring finger 4; polycomb complex protein BMI-1; RNF51; flvi-2/bmi-1; ring finger protein 51; polycomb group protein Bmi1; polycomb group RING finger protein 4; B lymphoma Mo-MLV insertion region 1 homolog; murine leukemia viral (bmi-1) oncogene homolog; PCGF4; FLVI2/BMI1; MGC12685; |
Gene ID : | 648 |
mRNA Refseq : | NM_005180 |
Protein Refseq : | NP_005171 |
MIM : | 164831 |
UniProt ID : | P35226 |
Products Types
◆ Recombinant Protein | ||
BMI1-1049M | Recombinant Mouse BMI1 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMI1-27487H | Recombinant Human BMI1, GST-tagged | +Inquiry |
BMI1-495H | Recombinant Human BMI1 Protein(1-250aa), GST-tagged | +Inquiry |
BMI1-316H | Recombinant Human BMI1 Protein, His-tagged | +Inquiry |
BMI1-2733H | Recombinant Human BMI1 protein(101-170 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
BMI1-8437HCL | Recombinant Human BMI1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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