Expand
Expand
| Cat.No.: | CCL25-31213TH |
| Product Overview: | Recombinant mature Human TECK. 127 amino acids with a predicted MWt 14.2 kDa. |
| Description: | This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. Alternative splicing results in multiple transcript variants. |
| Protein length: | 127 amino acids |
| Molecular Weight: | 14.200kDa |
| Source: | E. coli |
| Tissue specificity: | Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine. |
| Biological activity: | Determined by its ability to chemoattract Human monocytes using a concentration range of 1-10ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg. |
| Form: | Lyophilised:It is recommended to reconstitute CCL25-31213TH in sterile 18MO-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
| Purity: | by SDS-PAGE |
| Storage buffer: | pH: 7.40Constituents:0.28% Phosphate Buffer, 0.88% Sodium chloride |
| Storage: | Please see Notes section |
| Sequences of amino acids: | QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSRKNVSLL ISANSGL |
| Sequence Similarities: | Belongs to the intercrine beta (chemokine CC) family. |
| Gene Name: | CCL25 chemokine (C-C motif) ligand 25 [ Homo sapiens ] |
| Official Symbol: | CCL25 |
| Synonyms: | CCL25; chemokine (C-C motif) ligand 25; SCYA25, small inducible cytokine subfamily A (Cys Cys), member 25; C-C motif chemokine 25; Ck beta 15; Ckb15; TECK; TECKvar; thymus expressed chemokine; |
| Gene ID: | 6370 |
| mRNA Refseq: | NM_001201359 |
| Protein Refseq: | NP_001188288 |
| MIM: | 602565 |
| Uniprot ID: | O15444 |
| Chromosome Location: | 19p13.2 |
| Pathway: | Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; |
| Function: | CCR10 chemokine receptor binding; chemokine activity; hormone activity; |
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Download Datasheet
See All CCL25 Products
Download Datasheet