"CLIC1" Related Products

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Recombinant Human CLIC1, His-tagged

Cat.No.: CLIC1-27816TH
Product Overview: Recombinant full-length Human CLIC1 with N terminal His tag, amino acids 1-241, 261 amino acids with tag, MWt 29 kDa,
Description: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
Conjugation: HIS
Source: E. coli
Tissue specificity: Expression is prominent in heart, placenta, liver, kidney and pancreas.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, pH 8
Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAEEQPQVEL FVKAGSDGAK IGNCPFSQRL FMVLWLKGVT FNVTTVDTKR RTETVQKLCP GGQLPFLLYGTEVHTDTNKI EEFLEAVLCP PRYPKLAALN PESNTAGLDI FAKFSAYIKN SNPALNDNLE KGLLKALKVL DNYLTSPLPE EVDETSAEDEGVSQRKFLDG NELTLADCNL LPKLHIVQVV CKKYRGFTIP EAFRGVHRYL SNAYAREEFA STCPDDEEIE LAYEQVAKAL K
Sequence Similarities: Belongs to the chloride channel CLIC family.Contains 1 GST C-terminal domain.
Gene Name: CLIC1 chloride intracellular channel 1 [ Homo sapiens ]
Official Symbol: CLIC1
Synonyms: CLIC1; chloride intracellular channel 1; chloride intracellular channel protein 1; NCC27; p64CLCP;
Gene ID: 1192
mRNA Refseq: NM_001288
Protein Refseq: NP_001279
MIM: 602872
Uniprot ID: O00299
Chromosome Location: 6p21.3
Function: chloride channel activity; protein binding; voltage-gated chloride channel activity; voltage-gated ion channel activity;

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