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Recombinant Human ELK1, C-MYC-tagged

Cat.No. : ELK1-27228TH
Product Overview : Recombinant fragment, corresponding to amino acids 307-428 of Human ELK1, a maltose binding protein fusion protein with an amino-terminal polyhistidine tag and a c-terminal myc tag , 60 kDa.
  • Specification
  • Gene Information
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Description : This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Conjugation : c-myc
Source : E. coli
Tissue specificity : Lung and testis.
Form : Lyophilised:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute lyophilized in distilled water to a concentration of 0.2-1.0 mg/mL.
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: None
Storage : Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Belongs to the ETS family.Contains 1 ETS DNA-binding domain.
Gene Name : ELK1 ELK1, member of ETS oncogene family [ Homo sapiens ]
Official Symbol : ELK1
Synonyms : ELK1; ELK1, member of ETS oncogene family; ETS domain-containing protein Elk-1;
Gene ID : 2002
mRNA Refseq : NM_001114123
Protein Refseq : NP_001107595
MIM : 311040
Uniprot ID : P19419
Chromosome Location : Xp11.23
Pathway : Activated TLR4 signalling, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem;
Function : protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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