"FOSL1" Related Products

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Recombinant Human FOSL1, His-tagged

Cat.No.: FOSL1-28947TH
Product Overview: Recombinant full length Human FRA1 with His tag, approximately 29kDa, amino acids 1-271,
Description: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Conjugation: HIS
Source: E. coli
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the bZIP family. Fos subfamily.Contains 1 bZIP domain.
Gene Name: FOSL1 FOS-like antigen 1 [ Homo sapiens ]
Official Symbol: FOSL1
Synonyms: FOSL1; FOS-like antigen 1; fos-related antigen 1; fra 1;
Gene ID: 8061
mRNA Refseq: NM_005438
Protein Refseq: NP_005429
MIM: 136515
Uniprot ID: P15407
Chromosome Location: 11q13
Pathway: Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem; HTLV-I infection, organism-specific biosystem;
Function: protein binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;

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