Recombinant Human FOSL1, His-tagged FOSL1-28947TH

Recombinant Human FOSL1, His-tagged


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Recombinant Human FOSL1, His-tagged

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Cat.No. : FOSL1-28947TH
Product Overview : Recombinant full length Human FRA1 with His tag, approximately 29kDa, amino acids 1-271,
Description : The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Conjugation : HIS
Source : E. coli
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the bZIP family. Fos subfamily.Contains 1 bZIP domain.
Gene Name : FOSL1 FOS-like antigen 1 [ Homo sapiens ]
Official Symbol : FOSL1
Synonyms : FOSL1; FOS-like antigen 1; fos-related antigen 1; fra 1;
Gene ID : 8061
mRNA Refseq : NM_005438
Protein Refseq : NP_005429
MIM : 136515
Uniprot ID : P15407
Chromosome Location : 11q13
Pathway : Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem; HTLV-I infection, organism-specific biosystem;
Function : protein binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;

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