Recombinant Full Length Human FOSL1 Protein, C-Flag-tagged

• Cat.No.: FOSL1-2065HFL
• Product Overview: Recombinant Full Length Human FOSL1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 29.2 kDa
• AA Sequence: MFRDFGEPGPSSGNGGGYGGPAQPP AAAQAAQQKFHLVPSINTMSGSQEL QWMVQPHFLGPSSYPRPLTY PQYSPPQPRPGVIRALGPPPGVRRR PCEQISPEEEERRRVRRERNKLAAA KCRNRRKELTDFLQAETDKL EDEKSGLQREIEELQKQKERLELVL EAHRPICKIPEGAKEGDTGSTSGTS SPPAPCRPVPCISLSPGPVL EPEALHTPTLMTTPSLTPFTPSLVF TYPSTPEPCASAHRKSSSSSGDPSS DPLGSPTLLAL TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Wnt signaling pathway

Gene Information

• Gene Name: FOSL1 FOS like 1, AP-1 transcription factor subunit [ Homo sapiens (human) ]
• Official Symbol: FOSL1
• Synonyms: FRA; FRA1; fra-1
• Gene ID: 8061
• mRNA Refseq: NM_005438.5
• Protein Refseq: NP_005429.1
• MIM: 136515
• UniProt ID: P15407