Recombinant Human IFNG
Cat.No. : | IFNG-29196TH |
Product Overview : | Recombinant full length mature protein of Human Interferon gamma , 143 aa, 16.7kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia. |
Protein length : | 143 amino acids |
Molecular Weight : | 16.700kDa |
Source : | E. coli |
Tissue specificity : | Released primarily from activated T lymphocytes. |
Biological activity : | >?2?x?107?units/mg |
Form : | Lyophilised:Reconstitute?with?20ul?distilled?water. |
Purity : | by SDS-PAGE |
Storage buffer : | pH: 7.40Constituent:0.16% Sodium phosphate |
Storage : | Shipped at 4°C. After reconstitution store at -20oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the type II (or gamma) interferon family. |
Gene Name : | IFNG interferon, gamma [ Homo sapiens ] |
Official Symbol : | IFNG |
Synonyms : | IFNG; interferon, gamma; interferon gamma; |
Gene ID : | 3458 |
mRNA Refseq : | NM_000619 |
Protein Refseq : | NP_000610 |
MIM : | 147570 |
Uniprot ID : | P01579 |
Chromosome Location : | 12q14 |
Pathway : | ATF-2 transcription factor network, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; |
Function : | cytokine activity; interferon-gamma receptor binding; |
Products Types
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◆ Lysates | ||
IFNG-1007FCL | Recombinant Ferret IFNG cell lysate | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIFNG plays an important role in tumor immunotherapy, which can activate the immune response of tumor cells, promote apoptosis of tumor cells and inhibit the proliferation of tumor cells.
The development of drugs for IFNG is currently in clinical trials, including monoclonal antibodies against IFNG receptors and inhibitors against IFNG signaling pathways.
Studies have shown that IFNG can inhibit the occurrence of muscle atrophy, but the specific mechanism is not clear.
In clinical practice, the expression level of IFNG can be measured to predict the progression and prognosis of the disease, and to guide the choice of treatment regimen.
Yes, there are other coding variants in the IFNG gene that may have different functions and expression patterns.
Such as nutritional status, inflammation levels, etc. Yes, the expression of IFNG is affected by environmental factors, such as nutritional status, inflammation level, etc.
Customer Reviews (3)
Write a reviewIt is analyzed by X-ray crystallography or other crystallization techniques and has good crystallization properties.
Easy to attach to the surface of cells or materials.
IFNG products have a complete range of specifications for experimental designs of different sizes and needs.
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