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Recombinant Human IFNG

Cat.No. : IFNG-29196TH
Product Overview : Recombinant full length mature protein of Human Interferon gamma , 143 aa, 16.7kDa.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.
Protein length : 143 amino acids
Molecular Weight : 16.700kDa
Source : E. coli
Tissue specificity : Released primarily from activated T lymphocytes.
Biological activity : >?2?x?107?units/mg
Form : Lyophilised:Reconstitute?with?20ul?distilled?water.
Purity : by SDS-PAGE
Storage buffer : pH: 7.40Constituent:0.16% Sodium phosphate
Storage : Shipped at 4°C. After reconstitution store at -20oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the type II (or gamma) interferon family.
Gene Name : IFNG interferon, gamma [ Homo sapiens ]
Official Symbol : IFNG
Synonyms : IFNG; interferon, gamma; interferon gamma;
Gene ID : 3458
mRNA Refseq : NM_000619
Protein Refseq : NP_000610
MIM : 147570
Uniprot ID : P01579
Chromosome Location : 12q14
Pathway : ATF-2 transcription factor network, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem;
Function : cytokine activity; interferon-gamma receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the role of IFNG in tumor immunotherapy? 09/23/2022

IFNG plays an important role in tumor immunotherapy, which can activate the immune response of tumor cells, promote apoptosis of tumor cells and inhibit the proliferation of tumor cells.

What is the current progress in drug development for IFNG? 12/19/2021

The development of drugs for IFNG is currently in clinical trials, including monoclonal antibodies against IFNG receptors and inhibitors against IFNG signaling pathways.

How is IFNG related to muscle wasting? 12/02/2021

Studies have shown that IFNG can inhibit the occurrence of muscle atrophy, but the specific mechanism is not clear.

How can IFNG be used as a biomarker in clinical practice? 03/01/2021

In clinical practice, the expression level of IFNG can be measured to predict the progression and prognosis of the disease, and to guide the choice of treatment regimen.

Are there other coding variants in the IFNG gene? 07/12/2020

Yes, there are other coding variants in the IFNG gene that may have different functions and expression patterns.

Is the expression of IFNG affected by environmental factors? 05/26/2020

Such as nutritional status, inflammation levels, etc. Yes, the expression of IFNG is affected by environmental factors, such as nutritional status, inflammation level, etc.

Customer Reviews (3)

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Reviews
12/17/2022

    It is analyzed by X-ray crystallography or other crystallization techniques and has good crystallization properties.

    06/10/2022

      Easy to attach to the surface of cells or materials.

      04/02/2022

        IFNG products have a complete range of specifications for experimental designs of different sizes and needs.

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