|Product Overview :
||Recombinant IL17D fragment (Human), disulfide-linked homodimer with a total weight of 40.5 kDa, consisting of 370 amino acid residues.
||The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.
|Tissue specificity :
||Expressed preferentially in adipose, skeletal muscle and CNS.
||Lyophilised:Centrifuge the vial prior to opening.Reconstitute in water to a concentration of 0.5-1.0 mg/ml.This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
||>95% by SDS-PAGE
||Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
|Sequences of amino acids :
||APRAGRRPAR PRGCADRPEE LLEQLYGRLA AGVLSAFHHT LQLGPREQAR NASCPAGGRP ADRRFRPPTN LRSVSPWAYR ISYDPARYPR YLPEAYCLCR GCLTGLFGEE DVRFRSAPVY MPTVVLRRTP ACAGGRSVYT EAYVTIPVGC TCVPEPEKDA DSINSSIDKQ GAKLLLGPND APAGP
|Sequence Similarities :
||Belongs to the IL-17 family.