"IL2RB" Related Products


Recombinant Human Interleukin 2 Receptor, Beta

Cat. No. : IL2RB-1643H
Description : Interleukin 2 receptor beta, also known as IL2RB, is a novel glycoprotein that has the ability to bind IL-2 alone and to associate with Tac antigen (IL-2R alpha) to form high-affinity IL-2 receptors. IL-2R beta is expressed on both circulating T lymphocytes and large granular lymphocytes. IL-2R beta mediates the initial phase of induction of lymphokine activated killer (LAK), natural killer (NK), and proliferative activities.
Source : Sf 21 Insect Cells.
State Of Matter : Lyophilized.
Purity : >97% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Molecular Weight : The predicted molecular weight of Recombinant Human IL-2 sRβ is Mr 25 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 29-31 kDa.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
PDB rendering based on 2b5i. :

Gene Name : IL2RB interleukin 2 receptor, beta [ Homo sapiens ]
Synonyms : IL2RB; interleukin 2 receptor, beta; CD122; P70-75; interleukin 2 receptor beta; CD122 antigen; high affinity IL-2 receptor beta subunit; OTTHUMP00000028799; IL-2 receptor
Gene ID : 3560
mRNA Refseq : NM_000878
Protein Refseq : NP_000869
MIM : 146710
UniProt ID : P14784
Chromosome Location : 22q13
Pathway : Cytokine-cytokine receptor interaction; Endocytosis; Jak-STAT signaling pathway
Function : interleukin-2 receptor activity; receptor activity

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