"MYL2" Related Products

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Recombinant Human MYL2, His-tagged

Cat.No. : MYL2-28864TH
Product Overview : Recombinant full length human Myosin Light Chain 2 protein, fused to His tag at N terminus; 186 amino acids, 20.9kDa.
Description : Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Conjugation : HIS
Source : E. coli
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 5mM Calcium chloride, 20mM Tris, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MAPKKAKKRA GGANSNVFSM FEQTQIQEFK EAFTIMDQNR DGFIDKNDLR DTFAALGRVN VKNEEIDEMI KEAPGPINFT VFLTMFGEKL KGADPEETIL NAFKVFDPEG KGVLKADYVR EMLTTQAERF SKEEVDQMFA AFPPDVTGNL DYKNLVHIITHGEEKD
Sequence Similarities : Contains 3 EF-hand domains.
Gene Name : MYL2 myosin, light chain 2, regulatory, cardiac, slow [ Homo sapiens ]
Official Symbol : MYL2
Synonyms : MYL2; myosin, light chain 2, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; myosin regulatory light chain 2, ventricular/cardiac muscle isoform; cardiac ventricular myosin light chain 2; CMH10;
Gene ID : 4633
mRNA Refseq : NM_000432
Protein Refseq : NP_000423
MIM : 160781
Uniprot ID : P10916
Chromosome Location : 12q24.11
Pathway : CDC42 signaling events, organism-specific biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem;
Function : actin monomer binding; calcium ion binding; myosin heavy chain binding; protein binding; structural constituent of muscle;

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