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Recombinant Human PI4KB

Cat.No. : PI4KB-30364TH
Product Overview : Recombinant full length Human PI4 kinase beta with an N terminal proprietary tag; MWt 120 kDa.
  • Specification
  • Gene Information
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Description : Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation.
Protein length : 801 amino acids
Molecular Weight : 120.000kDa inclusive of tags
Source : Baculovirus infected sf9 cells
Tissue specificity : Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver.
Biological activity : The Specific activity of PI4KB-30364TH was determined to be 32 nmol/min/mg.
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.Contains 1 PI3K/PI4K domain.
Gene Name : PI4KB phosphatidylinositol 4-kinase, catalytic, beta [ Homo sapiens ]
Official Symbol : PI4KB
Synonyms : PI4KB; phosphatidylinositol 4-kinase, catalytic, beta; PIK4CB; phosphatidylinositol 4-kinase beta; PI4K BETA; pi4K92;
Gene ID : 5298
mRNA Refseq : NM_001198773
Protein Refseq : NP_001185702
MIM : 602758
Uniprot ID : Q9UBF8
Chromosome Location : 1q21
Pathway : 3-phosphoinositide biosynthesis, conserved biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Inositol phosphate metabolism, PI=>
Function : 1-phosphatidylinositol 4-kinase activity; ATP binding; kinase activity; nucleotide binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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