"PI4KB" Related Products


Recombinant Human PI4KB

Cat.No.: PI4KB-30364TH
Product Overview: Recombinant full length Human PI4 kinase beta with an N terminal proprietary tag; MWt 120 kDa.
Description: Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation.
Protein length: 801 amino acids
Molecular Weight: 120.000kDa inclusive of tags
Source: Baculovirus infected sf9 cells
Tissue specificity: Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver.
Biological activity: The Specific activity of PI4KB-30364TH was determined to be 32 nmol/min/mg.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.Contains 1 PI3K/PI4K domain.
Gene Name: PI4KB phosphatidylinositol 4-kinase, catalytic, beta [ Homo sapiens ]
Official Symbol: PI4KB
Synonyms: PI4KB; phosphatidylinositol 4-kinase, catalytic, beta; PIK4CB; phosphatidylinositol 4-kinase beta; PI4K BETA; pi4K92;
Gene ID: 5298
mRNA Refseq: NM_001198773
Protein Refseq: NP_001185702
MIM: 602758
Uniprot ID: Q9UBF8
Chromosome Location: 1q21
Pathway: 3-phosphoinositide biosynthesis, conserved biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Inositol phosphate metabolism, PI=>
Function: 1-phosphatidylinositol 4-kinase activity; ATP binding; kinase activity; nucleotide binding;

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