"TTR" Related Products

Native Human TTR

Cat.No.: TTR-31108TH
Product Overview: Full length Human Prealbumin purified from Human plasma; MWt 55kDa.
Description: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
Source: Human plasma
Species: Human
Form: Lyophilised:Please reconstitute with deionized water to the pre-lyophilization volume (lot specific).
Molecular Mass: 55kDa
Purity: >95% by SDS-PAGE
Storage: Shipped at 4°C . Store at -20°C .
Storage Buffer: Preservative: NoneConstituents: 50mM Sodium phosphate, 150mM Sodium chloride, pH 7.5
Gene Name: TTR transthyretin [ Homo sapiens ]
Official Symbol: TTR
Synonyms: TTR; transthyretin; PALB, prealbumin, amyloidosis type I; HsT2651; ATTR; carpal tunnel syndrome 1; thyroxine-binding prealbumin; prealbumin, amyloidosis type I; CTS; CTS1; PALB; TBPA;
Gene ID: 7276
mRNA Refseq: NM_000371
Protein Refseq: NP_000362
MIM: 176300
UniProt ID: P02766
Chromosome Location: 18q12.1
Pathway: Amyloids, organism-specific biosystem; Disease, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem;
Function: hormone activity; hormone binding; protein binding;

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