"TIMP1" Related Products


Recombinant Human metallopeptidase inhibitor 1, His-tagged

Cat. No.: TIMP1-287H
Product Overview: Recombinant Human TIMP-1 comprises a 184 amino acid fragment (24-207) corresponding to the mature TIMP-1 protein and is expressed inE. coliwith an aminoterminal hexahistidine tag.
Description: TIMP-1 is an inducible glycoprotein, which is synthesized by many different cell types. TIMP-1 binds in a reversible fashion to matrix metalloproteinases, with regions in the N-terminal domain binding to the MMP substrate-binding site. TIMP-1 also functions as erthyroid-potentiating activity via translocation to the nucleus and also in inhibiting apoptosis in B-cells.
Source: E.coli.
Purity: >95% by SDS-PAGE
Form: Liquid
Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Gene Name: TIMP1 TIMP metallopeptidase inhibitor 1 [ Homo sapiens ]
Synonyms: CLGI; EPA, EPO; HCI; TIMP; Erythroid-potentiating activity; tissue inhibitor of metalloprotease 1; collagenase inhibitor; metalloprotease inhibitor 1 precursor; tissue inhibitor of metalloproteases; FLJ90373; OTTHUMP00000023214; TIMP-1; Collagenase inhibitor; Erythroid-potentiating activity; TIMP metallopeptidase inhibitor 1; erythroid potentiating activity; tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor); tissue inhibitor of metalloproteinase 1; erythroid potentiating activity; fibroblast collagenase inhibitor.
Gene ID: 7076
mRNA Refseq: NM_003254
Protein Refseq: NP_003245
MIM: 305370
UniProt ID: P01033
Chromosome Location: Xp11.3-p11.23
Function: enzyme inhibitor activity; metalloendopeptidase inhibitor activity; protein binding

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