Native Human TIMP-1
Cat.No. : | TIMP1-92H |
- Specification
- Gene Information
- Related Products
Description : | The tissue inhibitor of metalloproteinases (TIMP-1) is a glycoprotein with a molecular mass of about 28-kDa. The secreted protein consists of 184 amino acids, six disuilfide bonds and two glycosylation sites containing N-linked oligosaccharides. TIMP-1 specifically inhibits the extracellular-matrix-egradingmetalloproteinases such as collagenase, gelatinase and stromelysin. It has no activity on mammalian membrane metallo-proteinases, procollagen peptidase, or on bacterial metalloproteinases such as thermolysin |
Source : | Human neutrophil granulocytes (Buffy Coat) |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 28.0 kDa |
Purity : | Purity by SDS-PAGE: ≥92% |
Usage : | For Research Use Only! Not For Use in Humans. |
Notes : | Centrifuge the vial prior to opening |
Storage : | -80°C |
Storage Buffer : | In 50 mM Tris-HCl, pH 7; 200 mM NaCl; 5 mM CaCl?; 1 μM ZnCl?; 0.05% Brij 35; 0,05% NaN? |
Shipping : | Dry Ice |
Gene Name : | TIMP1 TIMP metallopeptidase inhibitor 1 [ Homo sapiens ] |
Official Symbol : | TIMP1 |
Synonyms : | TIMP1; TIMP metallopeptidase inhibitor 1; CLGI, TIMP, tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor); metalloproteinase inhibitor 1; EPO; TIMP-1; collagenase inhibitor; erythroid potentiating activity; er |
Gene ID : | 7076 |
mRNA Refseq : | NM_003254 |
Protein Refseq : | NP_003245 |
MIM : | 305370 |
UniProt ID : | P01033 |
Chromosome Location : | Xp11.3-p11.23 |
Pathway : | Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Hemostasis, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; |
Function : | enzyme inhibitor activity; metal ion binding; metalloendopeptidase inhibitor activity; metalloendopeptidase inhibitor activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
Timp1-02M | Recombinant Mouse Timp1 Protein, His-tagged | +Inquiry |
TIMP1-1034M | Recombinant Mouse TIMP1 Protein, His-tagged | +Inquiry |
TIMP1-001H | Recombinant Human TIMP1 Protein, MBP-tagged | +Inquiry |
TIMP1-4536R | Recombinant Rhesus Macaque TIMP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
TIMP1-4491H | Recombinant Human TIMP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
TIMP1-30840TH | Native Human TIMP1 | +Inquiry |
TIMP1-91B | Active Native Bovine Thrombin | +Inquiry |
◆ Lysates | ||
TIMP1-2678HCL | Recombinant Human TIMP1 cell lysate | +Inquiry |
TIMP1-1490RCL | Recombinant Rat TIMP1 cell lysate | +Inquiry |
TIMP1-2376MCL | Recombinant Mouse TIMP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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