"Ppp1r1b" Related Products


Recombinant Rat Ppp1r1b, Phosphorylated

Cat. No.: Ppp1r1b-2634R
Product Overview: Recombinant Rat Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B is expressed inE. coliand phosphorylated on Thr34 by cAMP-dependent protein kinase (PKA).
Description: Midbrain dopaminergic neurons play a critical role in multiple brain functions, and abnormal signaling through dopaminergic pathways has been implicated in several major neurologic and psychiatric disorders. One well-studied target for the actions of dopamine is DARPP32. In the densely dopamine- and glutamate-innervated rat caudate-putamen, DARPP32 is expressed in medium-sized spiny neurons that also express dopamine D1 receptors.
Source: E. coli.
Form: White lyophilized solid.
Molar Mass: 32000Da.
Solubility: 50 mM Tris-HCl buffer, pH 7.0.
Purity: ≥95% by SDS-PAGE.
Storage: ≤ -20oC. Ship: Dry Ice Only.
Gene Name: Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B [ Rattus norvegicus ]
Ppp1r1b; protein phosphatase 1, regulatory (inhibitor) subunit 1B; dopamine- and cAMP-regulated neuronal phosphoprotein; dopamine- and cAMP-regulated phosphoprotein DARPP-32; neuronal phosphoprotein DARPP-32; protein phosphatase 1 regulatory subunit 1B; Darpp-32; Darpp32
Gene ID: 360616
mRNA Refseq: NM_138521
Protein Refseq: NP_612530
UniProt ID: Q6J4I0
Chromosome Location: 10q31
Function: phosphoprotein phosphatase inhibitor activity; receptor binding

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