Mouse IDO1 Inhibitor Screening Assay Kit
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Cat.No. : | Kit-1782 |
Product Overview : | L-tryptophan (L-Trp) is an essential amino acid necessary for protein synthesis in mammalian cells and the L-Trp to kynurenine (Kyn) pathway is firmly established as a key regulator of innate and adaptive immunity. Catabolism of L-Trp to Kyn maintains an immunosuppressive microenvironment by starving immune cells of L-Trp and releasing degradation products of L-Trp that have immunosuppressive functions. Indoleamine 2,3- dioxygenases (IDO1 & IDO2), two of the rate limiting enzymes in this pathway, are upregulated in many tumors, providing cancer cells with an avenue for immune evasion. |
Size : | 96 reactions |
Applications : | Useful for the study of mouse IDO1 enzymology, screening inhibitors and selectivity profiling. |
Storage : | Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
◆ Recombinant Protein
Ido1-1213M | Recombinant Mouse Ido1 Protein, MYC/DDK-tagged | +Inquiry |
IDO1-1419H | Recombinant Human IDO1 Protein (1-403 aa), His-tagged | +Inquiry |
IDO1-3829H | Recombinant Human IDO1 protein, GST-tagged | +Inquiry |
IDO1-085H | Recombinant Human IDO1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
Ido1-2126M | Recombinant Mouse Indoleamine 2,3-dioxygenase 1, His-tagged | +Inquiry |
|
◆ Lysates
IDO1-5300HCL | Recombinant Human IDO1 293 Cell Lysate | +Inquiry |
|
◆ Assay kits
Kit-2211 | Indoleamine 2,3-Dioxygenase 1 Activity Assay Kit | +Inquiry |
Kit-1763 | IDO1 Inhibitor Mechanism of Action Assay Kit | +Inquiry |
|
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2007 – 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy