Recombinant Human IDO1 Protein, MYC/DDK-tagged, C13 and N15-labeled
Cat.No. : | IDO1-085H |
Product Overview : | IDO1 MS Standard C13 and N15-labeled recombinant protein (NP_002155) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 45.3 kDa |
AA Sequence : | MAHAMENSWTISKEYHIDEEVGFAL PNPQENLPDFYNDWMFIAKHLPDLI ESGQLRERVEKLNMLSIDHLTDHKS QRLARLVLGCITMAYVWGKGHGDVR KVLPRNIAVPYCQLSKKLELPPILV YADCVLANWKKKDPNKPLTYENMDV LFSFRDGDCSKGFFLVSLLVEIAAA SAIKVIPTVFKAMQMQERDTLLKAL LEIASCLEKALQVFHQIHDHVNPKA FFSVLRIYLSGWKGNPQLSDGLVYE GFWEDPKEFAGGSAGQSSVFQCFDV LLGIQQTAGGGHAAQFLQDMRRYMP PAHRNFLCSLESNPSVREFVLSKGD AGLREAYDACVKALVSLRSYHLQIV TKYILIPASQQPKENKTSEDPSKLE AKGTGGTDLMNFLKTVRSTTEKSLL KEGTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | IDO1 indoleamine 2,3-dioxygenase 1 [ Homo sapiens (human) ] |
Official Symbol : | IDO1 |
Synonyms : | IDO1; indoleamine 2,3-dioxygenase 1; IDO; IDO-1; INDO; indoleamine 2,3-dioxygenase 1; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine-pyrrole 2,3-dioxygenase; EC 1.13.11.52 |
Gene ID : | 3620 |
mRNA Refseq : | NM_002164 |
Protein Refseq : | NP_002155 |
MIM : | 147435 |
UniProt ID : | P14902 |
Products Types
◆ Recombinant Protein | ||
IDO1-1419H | Recombinant Human IDO1 Protein (1-403 aa), His-tagged | +Inquiry |
Ido1-2126M | Recombinant Mouse Indoleamine 2,3-dioxygenase 1, His-tagged | +Inquiry |
IDO1-2077M | Recombinant Mouse IDO1 Protein (1-407 aa), His-tagged | +Inquiry |
IDO1-2645R | Recombinant Rat IDO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IDO1-4414M | Recombinant Mouse IDO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IDO1-5300HCL | Recombinant Human IDO1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1754 | Human IDO1 Cell-Based Assay Kit | +Inquiry |
Kit-1755 | Human IDO1 Fluorogenic Inhibitor Screening Assay Kit | +Inquiry |
Kit-1758 | Human IDO1 Inhibitor Screening Assay Kit (384) | +Inquiry |
Kit-2388 | Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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